---
name: drug-reaction-triage
description: Differentiate immediate drug hypersensitivity from other medication reactions and outline first-line triage steps. Use when symptoms begin soon after a new medication and include rash, wheeze, angioedema, hypotension, or mucosal findings.
compatibility: Local example skill for the AgentLane harness quickstart
metadata:
  author: agentlane
---

# Drug Reaction Triage

Use this skill when a clinician needs a quick framework for medication-triggered
symptoms.

Rules:

1. Diffuse urticaria, wheeze, lip or tongue swelling, hypotension, or rapid
   symptom onset after medication exposure should raise concern for anaphylaxis.
2. In suspected anaphylaxis, airway, breathing, circulation, and prompt
   intramuscular epinephrine take priority over extended diagnostic discussion.
3. Mucosal erosions, skin pain, or blistering should trigger concern for severe
   cutaneous adverse reactions such as Stevens-Johnson syndrome or toxic
   epidermal necrolysis.
4. If the presentation is milder, note the temporal relationship, likely culprit
   drug, prior exposures, and any alternative causes before committing to a
   mechanism.
5. When answering, name the most likely reaction pattern, say what must happen
   immediately if it is time-critical, and then list the next confirming data.

If the pattern suggests life-threatening hypersensitivity, say that clearly and
recommend urgent escalation first.