AutoGen
pipMicrosoft Research framework for multi-agent conversational AI.
CrewAI
pipMulti-agent orchestration framework with role-based agent definitions.
LangChain
pipMost-adopted framework for chaining LLM calls, tools, and agents. Python and JS/TS.
LlamaIndex
pipData framework for LLM apps — strongest in document ingestion and RAG pipelines.
PydanticAI
pipType-safe Python agent framework from the Pydantic team; MCP-native tool integration.