Use when authoring inside coding-os itself — core/, cli/, adapters/, templates/, or src/core/hooks/. Enforces three-layer mental model (DNA → mRNA → phenotype), graph-first edit…
UI component review patterns. Use when reviewing React components, hooks, props, state, styling, and accessibility.
Use when after batch effect removal and sample integration, when you have a normalized feature-by-sample abundance matrix (finalData) with corresponding sample group labels…
Use when after selecting statistically significant features from multi-assay LC-MS metabolomics datasets (e.g., via MB-VIP and permutation testing with p < 0.01).
Use when after importing raw metabolomics data (e.g., from Metabolon, Nightingale, SomaLogic, or Olink platforms) into a Metaboprep object, but before quality control or…
Use when you have normalized abundance data from LC-MS/MS for multiple samples classified into three or more discrete groups (e.
Use when you have peak-picked LC-MS metabolomics data in a tabular format (R data frame) with columns for mass-to-charge ratio, retention time, feature identifiers, adduct…
Use when after m/z grouping and pairwise alignment detection when you have a metabCombiner object containing candidate feature pair alignments and need to select a subset of…
Use when you have a raw metabolite abundance matrix (e.g., from MSPrep or another LC-MS/MS pipeline) with many features and samples, and you observe that a substantial fraction of…
Use when after drift correction and before imputation, when you have a MetaboSet object with LC-MS peak abundances and need to remove features with insufficient detection…
Use when after XCMS feature detection and retention time correction, when you have a feature table (CSV or XCMS object) with m/z and retention time values aligned across samples.
Use when you have two independent LC-MS untargeted metabolomic feature tables (e.
Use when after data merging and cleanup (blank removal) and before univariate or multivariate statistical analysis, when your merged feature table (samples as columns, metabolite…
Use when you have raw imzML and ibd (ion binary data) files from spatial mass spectrometry imaging and need to convert them into a standardized AnnData representation where m/z…
Use when you have a metabolomic SummarizedExperiment object with replicate QC (quality control) samples and need to remove non-reproducible metabolic features before phenotype…
Use when when you have completed feature detection in MZmine3 or similar tools and produced a feature quantification table (rows = features, columns = samples with intensity…
Use when immediately after executing the MetaboAnalystR 4.0 unified LC-MS workflow (feature detection and quantification module) on raw mzML or netCDF data.
Use when you have selected a subset of ReDU public tandem MS files with GNPS chemical annotations (level 2 or 3 spectral library matches) and wish to explore sample relationships…
Use when you have a metabolite intensity matrix (rows=metabolites or peaks, columns=samples) paired with metabolite-to-pathway or metabolite-to-feature-group annotations, and you…
Use when you have two or more CSV feature tables from independent metabolomic experiments (each with RT, m/z, intensity, isotope, and adduct columns), and you need to merge them…
Use when after feature detection and peak alignment have produced a feature table with zero or missing values across samples.
Use when after quality control, filtering, and normalization of an MS-DIAL-derived
Use when when you have preprocessed LC-MS/MS data (MGF file with MS1 and MS2 spectra and a feature abundance table from MZmine2 or similar peak detection tool) and need to perform…
Use when after completing feature annotation and reaction assignment in an untargeted metabolomics workflow, specifically when you have a feature-by-sample intensity matrix…
Use when you need to create realistic, diverse chemical populations for simulating LC-MS/MS acquisition strategies in a virtual environment.
Use when you have raw metabolomics mass spectrometry data in mzML or mzXML format and need to extract, align, and normalize metabolic features across multiple samples or…
Use when after XCMS peak picking and fillPeaks() when you have xcmsEIC and filled xcmsSet objects and need to systematically flag low-quality or unreliable peak integrations prior…
Use when when you have raw profile LC-MS data in .mzML format and need to prepare regions of interest (ROI) as input for a CNN-Transformer peak detection network.
Use when after drift correction and before missing value imputation when your LC-MS peak table contains features with variable detection rates across samples.
Use when you have fitted an MB-PLS model on multi-assay LC-MS intensity data (e.g., HPOS, LPOS, LNEG), computed MB-VIP scores for all features, and need to identify which features…
Use when you have a raw feature table (TSV/CSV) derived from LC-MS peak detection (e.
Use when when you have a feature intensity table (samples × compounds) from targeted or non-targeted metabolomics and need to prepare it for statistical modeling or multivariate…
Use when a task needs the judgment of a Model Maker, Metal and Plastic — checking whether a machined or hand-fabricated prototype's features are actually achievable by the…
Writes Gherkin .feature files from a user story so non-technical stakeholders can sign off on behavior. Use before implementing any user-visible behavior change.
Use when the task involves defining, calculating, or implementing business metrics or KPIs. Triggers include KPI definition, SQL metric logic, Excel formula for a business metric,…
Decompose a north-star metric into a driver tree — the inputs and sub-inputs that actually move it — so a team knows which levers to pull.
Port ML models into mflux/MLX with correctness-first validation, then refactor toward mflux style.
Use when positioning a Management Science (INFORMS) manuscript in its literature — joining the right Department's conversation, citing canonical analytical and empirical work in…
Use when when you have paired microbiome-metabolome datasets where only a subset of metabolites carry curated biochemical annotations (e.
Use when a task needs the judgment of a Microsystems Engineer — sizing a MEMS actuator's usable travel against electrostatic pull-in, checking a layout against a foundry's DRIE…
Map this token system to or from any external design system (Material Design 3, Apple HIG, Fluent, Carbon, Ant, shadcn/ui, Radix, Chakra, Mantine, Bootstrap…) — adopt their look,…
Orchestrates end-to-end feature migration from legacy repositories to modern target repositories. Coordinates specialized skills (legacy-context-engineer,…
Data-model rules that make a schema importable from day one, so the migration-import-engineer is never blocked on missing columns.
Migration specialist for zero-downtime schema changes, data migrations, and backward-compatible evolutionUse when "migration, schema change, database migration, zero downtime,…
Sistem Perencanaan PRD (State Machine) untuk memproses ide, kuesioner, mindmap, dan menghasilkan dokumen PRD serta Task List.
One repeatable pass that makes the milestone report's CLIMB and ROADMAP retirable by the RSI loop — the milestone counterpart of quality-score (code) and stability-score (trust…
READ-ONLY roadmap rollup for PRD_ROADMAP.md conventions: parses "- [ ]" checkboxes, ☐/☑ table glyphs, ~~struck~~ items (dropped, NEVER open), milestone headings; per-milestone…
Use for UI/UX design, frontend implementation, visual redesign, product interaction, shadcn/ui, creative web experiences, responsive/adaptive interfaces, accessibility, animation,…
Use when positioning a Mind article against the existing philosophical literature so the thesis reads as a genuine move in a live debate.
みんなのFX Webトレーダーをcmux-browserで操作するスキル。FX注文（成行・指値）、ポジション照会、決済、口座状況確認を自動化する。yfinanceで通貨ペアのリアルタイムレート取得も可能。Use when trading on みんなのFX, placing FX orders, checking positions, managing…
Buat Product Requirement Document singkat dan padat untuk memulai proyek baru. Gunakan ketika: user minta buat PRD, user mau buat produk baru, user minta ringkasan produk, user…
Create a compact SPEC.md for fast solo AI-engineering projects when the goal is clear enough to define behavior, constraints, and verification without full PRD ceremony.
Fetch and triage the latest unread RSS/news entries from a Miniflux instance via its REST API using an API token.
Manage Miniflux - Modern minimalist feed reader via REST API. Use for listing feeds and entries, creating/removing subscriptions, searching articles, managing categories, and…
Use when designing database schemas from business requirements, translating vague requirements into concrete SQL definitions, or validating database designs with non-technical…
Use to keep code MINIMAL and right-sized for AI coding agents. DO — keep an in-progress change minimal (reuse before adding, subtract, avoid the wrong abstraction, check blast…
Expert-level frontend architect and UI/UX design system integration guide. A minimalist modernist design system that helps seamlessly integrate a precise design system into…
Produce one minimalist product film from authorized product assets, a fact and claim ledger, independent product anchor photos, sparse composition, timed beats, approved copy,…
Generates structured legal and regulatory summaries for mining and land use projects covering permits, environmental compliance, mineral rights, stakeholder obligations, and risk…
Orchestrate multi-agent Claude Code teams with Minoan-Semitic naming — auto-discover project context (CLAUDE.md, roadmaps, plans, issues) and generate named team configurations…