Use when you have LC-MS/MS data preprocessed with MZmine2 into an MGF file (containing MS1 and MS2 spectra) and a feature table (peak areas per sample), and you want to relate MS1…
Use when you have collected or parsed 1H and 13C NMR peak data (chemical shift values and intensities) and need to submit it to the SMART 3 /api/smart3/search endpoint or similar…
Use when when you have an unknown metabolite compound with mass spectral data, have retrieved candidate structures from a molecular structure database (PubChem, HMDB), and have…
Use when you have retrieved multiple candidate structures from a molecular structure database (e.g., PubChem, HMDB) for an unknown compound, and you have predictions of…
Convert between IUPAC names, SMILES strings, molecular formulas, and common names for chemical compounds.
Use when after applying biotransformation rules to generate candidate product structures from input molecules, when the same transformed structure can be produced via multiple…
Use when when you have a set of molecular structures (N-Me derived unsaturated sterol lipids or structurally similar organic molecules with C=C bonds) represented as SMILES or…
Use when you have SMILES strings or molecular structure files (e.g., from a synthetic drug database) and need to feed them into a deep learning model like PS2MS, NEIMS, or DeepEI…
Use when when you have raw molecular structures in SMILES or SDF format that must be prepared as input to a descriptor-based classifier (e.g., BitterPredict).
Analyzes events through chemistry lens using molecular structure, reaction mechanisms, thermodynamics, kinetics, and analytical techniques (spectroscopy, chromatography — from…
Analyzes events through chemistry lens using molecular structure, reaction mechanisms, thermodynamics, kinetics, and analytical techniques (spectroscopy, chromatography — from…
Use when when you have sum-normalized peak-abundance matrices from FT-ICR MS data with assigned molecular formulas and need to compare metabolite diversity between treatment…
Visualize ChIP-seq data using deepTools, Gviz, and ChIPseeker. Create heatmaps, profile plots, and genome browser tracks.
Use when when you need to simulate LC-MS/MS data for fragmentation strategy development and do not have (or wish to augment) real experimental chromatograms.
Use when you have retention time predictions from a source chromatographic method and need to predict retention times for a target chromatographic method, but have limited…
Use when you have experimental RT measurements from a source chromatographic method and need to predict RTs for the same molecules on a target chromatographic method, but lack a…
Search research papers and get publication details from Clarity Protocol. Use when the user asks to search research papers, find publications, PubMed referen...
Use when when you have multi-omic TWIM-MS data (raw or processed arrival-time records) and have already assigned features or detected ion features to biomolecular classes (e.
Use when after identifying putative BGC-encoded precursor peptides from a genome assembly via MetaMiner's BGC identifier, when preparing a RiPP structure database for downstream…
Use when you have a feature table with assigned biomolecular class labels (e.g., from preceding class assignment step) and raw ion mobility arrival time measurements from TWIM-MS…
Use when you have a CSV or Excel file containing chemical structure descriptors for one or more molecules, and you want to obtain binary bitter/not-bitter predictions for each…
Comprehensive collection of 128+ ready-to-use scientific skills for Claude enabling research across biology, chemistry, medicine, genomics, and advanced analysis domains.
Semantic Similarity Index for disease research literature using PubMedBERT embeddings
Designs adaptive clinical trials including group-sequential (O'Brien-Fleming, Pocock, Lan-DeMets spending), sample-size re-estimation (blinded Friede-Kieser, unblinded Cu — from…
Computes sample size and power for clinical trials including continuous, binary, and time-to-event endpoints; superiority, non-inferiority, and equivalence designs; FDA 2 — from…
Generate professional clinical decision support (CDS) documents for pharmaceutical and clinical research settings, including patient cohort analyses (biomarker-stratified — from…
Generate professional clinical decision support (CDS) documents for pharmaceutical and clinical research settings, including patient cohort analyses (biomarker-stratified — from…
Guidelines for clinical decision support (CDS) documents: biomarker-stratified cohort analyses and GRADE-graded treatment reports.
Generate professional clinical decision support (CDS) documents for pharmaceutical and clinical research settings, including patient cohort analyses (biomarker-stratified — from…
Generate professional clinical decision support (CDS) documents for pharmaceutical and clinical research settings, including patient cohort analyses (biomarker-stratified — from…
Generate professional clinical decision support (CDS) documents for pharmaceutical and clinical research settings, including patient cohort analyses (biomarker-stratified — from…
Generate professional clinical decision support (CDS) documents for pharmaceutical and clinical research settings, including patient cohort analyses (biomarker-stratified — from…
Foundations of clinical psychology and psychopathology. Covers anxiety disorders (generalized anxiety, panic, phobias, OCD, PTSD), depressive disorders (major depression,…
Clinical variant interpretation using ClinVar, ACMG guidelines, and pathogenicity predictors. Prioritize variants for diagnostic and research applications.
Use when a task needs the judgment of a board-certified Clinical Neuropsychologist — building a neuropsychological battery to localize a brain-behavior deficit, adjudicating…
Write comprehensive clinical reports including case reports (CARE guidelines), diagnostic reports (radiology/pathology/lab), clinical trial reports (ICH-E3, SAE, CSR), an — from…
Use when designing a prospective clinical study before submission — selecting and classifying endpoints (primary / key-secondary / exploratory, with surrogate-endpoint flagging),…
Use when a task needs the judgment of a Clinical Research Coordinator — managing patient recruitment/enrollment against a trial's screen-fail rate, handling a protocol deviation,…
Avoid common methodological mistakes in clinical research with MIMIC-IV and eICU databases. Covers immortal time bias, information leakage, selection bias, and other critical…
Verifies clinical claims and citations: PMID/DOI validity, claim accuracy, and evidence-level wording. Use when the user wants existing content fact-checked.
Batch extracts and verifies structured information (PMID, title, abstract, methodology, results, etc.) from clinical research literature using PMIDs.
Drafts U.S. clinical trial agreements governing sponsor–site–investigator relationships under FDA rules (21 CFR Parts 50, 56, 312) and ICH-GCP E6(R2).
Drafts U.S. clinical trial Investigator Agreements between sponsors/CROs and principal investigators or institutions for FDA-regulated drug, biologic, or device studies.
Generate clinical trial protocols for medical devices or drugs through a modular, waypoint-based architecture with research-only and full protocol modes.
Align CLIP-seq reads to the genome with crosslink site awareness. Use when mapping preprocessed CLIP reads for peak calling. — from science/biology-medicine
Align CLIP-seq reads to the genome with crosslink site awareness. Use when mapping preprocessed CLIP reads for peak calling. — from majiayu000/claude-skill-registry
Use when you have preprocessed MS/MS spectral data (normalized peak intensities and m/z values) in memory or on disk, a trained CNN model checkpoint available, and you ne — from…
Detect copy number variations from whole genome sequencing data and generate publication-quality genome-wide CNV plots.
Constraint-based metabolic modeling (COBRA). FBA, FVA, gene knockouts, flux sampling, SBML models, for systems biology and metabolic engineering analysis.
Constraint-based metabolic modeling (COBRA). FBA, FVA, gene knockouts, flux sampling, SBML models, for systems biology and metabolic engineering analysis. — from bg-szy/TOP-SKILLS
Constraint-based metabolic modeling (COBRA). FBA, FVA, gene knockouts, flux sampling, SBML models, for systems biology and metabolic engineering analysis.
Constraint-based metabolic modeling (COBRA). FBA, FVA, gene knockouts, flux sampling, SBML models, for systems biology and metabolic engineering analysis.
Constraint-based metabolic modeling (COBRA). FBA, FVA, gene knockouts, flux sampling, SBML models, for systems biology and metabolic engineering analysis.
Constraint-based (COBRA) analysis of genome-scale metabolic models: FBA, FVA, knockouts, flux sampling, production envelopes, gapfilling, media optimization.
Constraint-based metabolic modeling (COBRA). FBA, FVA, gene knockouts, flux sampling, SBML models, for systems biology and metabolic engineering analysis.
Use when you have a set of molecular structures in SMILES format that require CCS prediction for metabolite annotation in untargeted mass spectrometry workflows.
Use when when you have peak-abundance .csv files and assigned molecular formula data from FT-ICR MS preprocessing, and you need to verify that a published pipeline's runtime…
Generates complete comorbidity-oriented shared-biomarker bioinformatics research designs from a user-provided disease pair and validation direction.
比较基因组与进化分析 skill。用于 ortholog inference、synteny、whole-genome duplication、positive selection、dN/dS、HGT、ancestral reconstruction、annotation transfer 和跨物种功能比较。
Use when when you have a binned Hi-C cooler file, an associated eigenvector track (from prior eigs_cis calculation), and need to measure how strongly the genome is partitioned…