Trigger when the user asks for explanations of web development concepts, code breakdowns, or learning guidance.
Provide proven marketing strategies and growth ideas for SaaS and software products, prioritized using a marketing feasibility scoring system. — from bg-szy/TOP-SKILLS
Lip-sync a face to a specific audio track on RunComfy via the `runcomfy` CLI. Routes across ByteDance OmniHuman (audio-driven full-body avatar from a portrait + audio), S — from…
Build clustered heatmaps for expression matrices and other features-by-samples data with rigorous distance/linkage/scaling choices, robust color mapping, optimal leaf ordering,…
Process and analyze tissue images from spatial transcriptomics data using Squidpy. Extract image features, segment cells/nuclei, and compute morphological features from H — from…
Generate alignment statistics using samtools flagstat, stats, depth, coverage, and mosdepth. Use when assessing alignment quality, calculating coverage, or generating QC reports.
Structures biological experiments so inference is valid by construction, covering Fisher's principles (randomization, replication, local control), the…
Perform statistical modeling and regression analysis on biomedical datasets. Supports linear regression, logistic regression (binary/ordinal/multinomial), mixed-effects models,…
Assesses genetic health of populations for conservation with Ne estimation across time horizons (LDNe NeEstimator V2 option-file API + SNeP physical-linkage correction; recent…
Browser automation for AI agents via inference.sh. Navigate web pages, interact with elements using @e refs, take screenshots, record video.
Benchling R&D platform integration. Access registry (DNA, proteins), inventory, ELN entries, workflows via API, build Benchling Apps, query Data Warehouse, for lab data m — from…
Build whole-genome alignments using Progressive Cactus (Armstrong 2020 reference-free clade-level WGA), Minigraph-Cactus (Hickey 2024 pangenome-aware), LASTZ chain/net (U — from…
Use when you need to run a binary, trace execution, or observe runtime behavior. Runtime analysis via QEMU emulation, GDB debugging, and Frida hooking - syscall tracing ( — from…
Create portable bioinformatics pipelines with Workflow Description Language (WDL) using Cromwell or miniwdl execution engines.
End-to-end Hi-C analysis workflow from contact pairs to compartments, TADs, and loops. Covers cooler matrices, cooltools analysis, and visualization.
Prepare Stitch screen-generation, edit, image-to-design, and variant prompts with verified tool checks and design-system-aware wording.
Infer gene regulatory networks (GRNs) from gene expression data using scalable algorithms (GRNBoost2, GENIE3).
Call structural variants (SVs) from sequencing data using Manta, Delly, GRIDSS, and LUMPY. Detects deletions, insertions, inversions, duplications, and translocations too large…
Use when starting any conversation - establishes how to find and use skills, requiring Skill tool invocation before ANY response including clarifying questions — from…
Iterate on a PR until CI passes. Use when you need to fix CI failures, address review feedback, or continuously push fixes until all checks are green.
Toolkit for styling artifacts with a theme. These artifacts can be slides, docs, reportings, HTML landing pages, etc.
Load and parse mass spectrometry data formats including mzML, mzXML, and quantification tool outputs like MaxQuant proteinGroups.txt.
Call HLA alleles from NGS data using OptiType, HLA-HD, or arcasHLA for immunogenomics applications. Use when determining HLA genotype for transplant matching, neoantigen…
Quantify transcript expression using pseudo-alignment with Salmon or kallisto. Use when quantifying transcripts with Salmon or kallisto. — from bg-szy/TOP-SKILLS
Guided statistical analysis with test selection and reporting. Use when you need help choosing appropriate tests for your data, assumption checking, power analysis, and A — from…
Visualize copy number profiles, segments, allele-specific tracks, and cohort patterns from CNVkit, GATK, ASCAT, FACETS, Sequenza, and other callers.
Detect somatic and germline copy number variants from targeted, exome, and whole-genome sequencing with CNVkit, a read-depth caller that combines on-target and off-target…
Use when encountering any bug, test failure, or unexpected behavior, before proposing fixes — from bg-szy/TOP-SKILLS
Annotate CNVs with genes, pathways, and clinical significance. Use when interpreting CNV calls or identifying affected genes from copy number analysis.
Create AI marketing videos for ads, promos, product launches, and brand content. Models: Veo, Seedance, Wan, FLUX for visuals, Kokoro for voiceover.
Linear issue tracking integration - Create, update, and manage Linear issues and projects using the GraphQL API
Gene and region-based rare-variant aggregation - burden/collapsing, SKAT, SKAT-O, ACAT-V/ACAT-O, annotation-weighted STAAR - with regenie (--vc-tests), SAIGE-GENE+, and t — from…
Systematically debug code issues using proven methodologies. Use when encountering errors, unexpected behavior, or performance problems.
Detects putative ligand-binding pockets and druggable cavities de novo on an apo protein structure with fpocket, P2Rank, CASTp, and DoGSiteScorer, ranking them by…
Comprehensive toolkit for creating, analyzing, and visualizing complex networks and graphs in Python.
Post-translational modification analysis including phosphorylation, acetylation, and ubiquitination. Covers site localization, motif analysis, and quantitative PTM analys — from…
Remove sequencing adapters from FASTQ files using Cutadapt and Trimmomatic. Supports single-end and paired-end reads, Illumina TruSeq, Nextera, and custom adapter sequenc — from…
Data visualization with chart selection, color theory, and annotation best practices. Covers chart types (bar, line, scatter, heatmap), axes rules, and storytelling with — from…
Molecular featurization for ML (100+ featurizers). ECFP, MACCS, descriptors, pretrained models (ChemBERTa), convert SMILES to features, for QSAR and molecular ML.
Run 250+ AI apps via inference.sh CLI - image generation, video creation, LLMs, search, 3D, Twitter automation.
Generate images with Google Gemini 3.1 Flash Image Preview (Nano Banana 2) via inference.sh CLI. Capabilities: text-to-image, image editing, multi-image input (up to 14 i — from…
Query ClinicalTrials.gov via API v2. Search trials by condition, drug, location, status, or phase. Retrieve trial details by NCT ID, export data, for clinical research an — from…
Estimate reviewed beverage quantities for a hosted event. Use when a host supplies guest count, duration, beverage mix, package yields, and an approved planning assumption.
End-to-end eDNA metabarcoding from raw amplicons to community ecology. Covers QC, primer removal (mandatory before DADA2 filterAndTrim), denoising with OBITools3 v3 (obi stats…
Plan lifecycle management for Codex plans stored in $CODEX_HOME/plans (default ~/.codex/plans). Use when a user asks to create, find, read, update, delete, or manage plan…
Builds Agent-to-Agent (A2A) servers and clients following Google's open protocol for agent interoperability.
Generate AI videos on RunComfy via the `runcomfy` CLI — a smart router across the full video-model catalog: HappyHorse 1.0 (Arena #1, native in-pass audio), Wan-AI Wan 2- — from…
EU MDR 2017/745 regulation specialist and consultant for medical device requirement management. Provides comprehensive MDR compliance expertise, gap analysis, technical d — from…
Build and interpret polygenic risk scores (PRS) for complex diseases using GWAS summary statistics. Calculates genetic risk profiles, interprets PRS percentiles, and assesses…
Use when executing implementation plans with independent tasks in the current session — from bg-szy/TOP-SKILLS
Maps query single-cell data to reference atlases using scArches transfer learning with scVI and scANVI models.
Calls HLA class I and class II alleles at 2/4/6/8-field resolution from WGS/WES/RNA-seq/long-read data using OptiType, HLA-LA, T1K, Polysolver, HLA-HD, arcasHLA, StarPhase, or…
Detect ribosome pausing and stalling sites from Ribo-seq data at codon resolution. Use when studying translational regulation, identifying pause sites, or analyzing codon — from…
Cleans a shotgun metagenome of everything that is not the target community before profiling - host-read depletion (Hostile, bowtie2/T2T-CHM13), reagent/kitome contamination…
Call accessible chromatin regions from ATAC-seq data using MACS3 with ATAC-specific parameters. Use when identifying open chromatin regions from aligned ATAC-seq BAM file — from…
Direct REST API access to KEGG (academic use only). Pathway analysis, gene-pathway mapping, metabolic pathways, drug interactions, ID conversion.
When the user wants to create, optimize, or audit the API introduction/overview page. Also use when the user mentions "API page," "API landing page," "/api page," "API overview,"…
Browser automation using Playwright MCP. Navigate websites, fill forms, click elements, take screenshots, and extract data.
Infer pathogen transmission networks and identify likely transmission pairs using TransPhylo and outbreak reconstruction algorithms.
Preprocessing and harmonization of multi-omics data before integration. Covers normalization, batch correction, feature alignment, and missing value handling across data — from…