This skill performs genome-wide DNA methylation profiling. It supports single-sample and multi-sample workflows to compute methylation density distributions, genomic feature…
Run a multi-perspective Mind Council deliberation on any question, decision, or creative challenge. Use this skill whenever the user wants diverse viewpoints, needs help — from…
This skill detects hierarchical (nested) TAD structures from Hi-C contact maps (in .cool or mcool format) using OnTAD, starting from multi-resolution .mcool files.
Transform vague or incomplete user stories into sprint-ready stories with clear acceptance criteria, test scenarios, and technical guidance.
Professional API design skill covering RESTful APIs, GraphQL, API versioning, authentication, idempotency, and API documentation best practices.
This skill should be used when users want to create powerful AI agents comparable to Claude Code or sonph-code.
This skill implements AI agents with MCP (Model Context Protocol) server integration using the OpenAI Agents SDK.
Guide for completing Coq proofs involving arithmetic properties like addition commutativity. This skill should be used when working on Coq proof files that require proving…
This skill should be used when implementing graceful error handling and user confirmations in both backend and frontend, including friendly tool not found messages, action…
This skill should be used when the user asks to "create an agent", "add an agent", "write a subagent", "agent frontmatter", "when to use description", "agent examples", " — from…
Use this skill when you need to gather comprehensive documentation and best practices for frameworks, libraries, or dependencies in your project.
Use this skill when the user asks "block info", "what's in block", "latest block", "get block details", or mentions viewing block data on EVM chains (Ethereum, Polygon, Arbitrum,…
Package conversation research into a GSD-ready mission package. Produces a three-stage Vision → Research → Mission pipeline as a LaTeX PDF following GSD/NASA SE methodolo — from…
Use this skill when preparing P&L statements, balance sheets, cash flow reports, board decks, or KPI dashboards.
Use this skill when users need to analyze competitors, monitor market movements, benchmark features/pricing, identify market gaps, or understand competitive positioning — from…
When you need to understand the project's core mandate, operational rules, or "Constitution". Use this skill to align with the project's identity and strict coding standards.
Guide for discovering and using MCP tools via the discover_tools meta-tool. Use this skill when asked to perform tasks that require finding the right tools, when you see — from…
GPU-accelerated pipeline for detecting, tracking, and classifying humans in dashcam footage. This skill should be used when users need to extract human presence from videos,…
Create beautiful visual art in .png and .pdf documents using design philosophy. You should use this skill when the user asks to create a poster, piece of art, design, or — from…
Use this skill when you need to research and gather external best practices, documentation, and examples for any technology, framework, or development practice.
Use this skill when you writing commands, hooks, skills for Agent, or prompts for sub agents or any other LLM interaction, including optimizing prompts, improving LLM out — from…
Comprehensive citation management for academic research. Search Google Scholar and PubMed for papers, extract accurate metadata, validate citations, and generate properly — from…
Detect explicit user_id parameters in functions to identify potential opportunities for using ambient context.
INVOKE THIS SKILL when your Deep Agent needs memory, persistence, or filesystem access. Covers StateBackend (ephemeral), StoreBackend (persistent), FilesystemMiddleware, and…
Analyzes narrative text and files to identify and remove AI-generated signals while preserving authentic voice and style.
Solubility-optimized protein sequence design using SolubleMPNN. Use this skill when: (1) Designing for E.
This skill should be used when the user asks to "create a hook", "write hook config", "add hooks.json", "configure event hooks", "create PreToolUse hook", "add SessionStart hook",…
Use this skill when designing APIs, choosing between REST/GraphQL/gRPC, writing OpenAPI specs, implementing pagination, versioning endpoints, or structuring request/response…
Run structured What-If scenario analysis with multi-branch possibility exploration. Use this skill when the user asks speculative questions like "what if...", "what would — from…
This skill should be used when the user asks to \"start a data science project\", \"brainstorm analysis\", \"plan a data analysis\", or wants to clarify analysis requirements.
Brief description of what this skill does and when to use it. Be specific about capabilities and use cases to help agents decide when to load this skill.
Generate format-controlled research reports with evidence tracking, citations, and iterative review. This skill should be used when users request a research report, literature…
ALWAYS apply these hints automatically in your responses. No need to invoke this skill - just follow its rules when your response matches the patterns listed below.
Validates skills against production-level criteria with 9-category scoring. This skill should be used when reviewing, auditing, or improving skills to ensure quality standards.
This skill should be used when executing plan tasks autonomously, implementing features using TDD, running the red-green-refactor cycle, handling code review loops, or dealing…
This skill should be used when the user asks to "understand context", "explain context windows", "design agent architecture", "debug context issues", "optimize context us — from…
Alibaba Cloud API reference for developing aero-cli. Use this skill when adding new cloud provider features, fixing API calls, or extending FC/RDS/Redis/OSS/DNS/VPC integrations.
Autonomous biomedical AI agent framework for executing complex research tasks across genomics, drug discovery, molecular biology, and clinical analysis.
Master high-performance rendering for large datasets with Datashader. Use this skill when working with datasets exceeding 100M+ points, optimizing visualization performance, or…
Tools are how AI agents interact with the world. A well-designed tool is the difference between an agent that works and one that hallucinates, fails silently, or costs 10 — from…
Use this skill when facing complex problems requiring rigorous reasoning, systematic decomposition, or factual verification.
This skill should be used when the user asks to "write system prompt", "configure SystemPromptGenerator", "prompt engineering", "background steps output_instructions", "improve…
ALWAYS use this skill when user needs ANY API functionality (AI models, image generation, video, audio, text processing, etc.).
Quantum computing framework for building, simulating, optimizing, and executing quantum circuits. Use this skill when working with quantum algorithms, quantum circuit design,…
This skill should be used when the user asks to "create a task in Things", "add a todo to Things 3", "manage Things projects", "schedule a task", "complete a todo", "delete a task…
[Task Mgmt] A Skill that segments subtasks into more granular, actionable items before starting work.
Guide for performing Markov Chain Monte Carlo (MCMC) sampling using RStan or PyStan. This skill should be used when implementing Bayesian statistical models, fitting hierarchical…
Fetches official documentation for external libraries and frameworks (React, Next.js, Prisma, FastAPI, Express, Tailwind, MongoDB, etc.) with 60-90% token savings via content-type…
Use this skill when the user wants to analyze something and needs help choosing the right approach, persona, and command sequence.
This skill should be used when developing, optimizing, testing, or submitting algorithms for The Innovation Game challenges (3-SAT, CVRP, Knapsack).
This skill should be used when working with single-cell omics data analysis using scvi-tools, including scRNA-seq, scATAC-seq, CITE-seq, spatial transcriptomics, and othe — from…
Autonomous AI coding orchestration using the Ralph Wiggum technique and Ralphy CLI. This skill should be used when running AI agents in continuous loops until tasks complete,…
This skill should be used when the user asks to 'verify sources', 'check citations', 'fact-check footnotes', 'verify quotes', 'source check', 'are my cites real', 'check for…
Scanpy is a scalable Python toolkit for analyzing single-cell RNA-seq data, built on AnnData. Apply this skill for complete single-cell workflows including quality contro — from…
Use this skill whenever the user wants to set up, configure, or refactor TypeORM within a NestJS TypeScript project, including data sources, entities, migrations, repositories,…
This skill should be used when the user asks to "implement LLM-as-judge", "compare model outputs", "create evaluation rubrics", "mitigate evaluation bias", or mentions di — from…
Design and implement RESTful API endpoints with proper HTTP methods, status codes, and consistent naming conventions.
This skill should be used when the user asks to "analyze competitors", "assess competitive landscape", "identify differentiation", "evaluate market positioning", "apply P — from…
Use this skill for requests related to Pydantic AI framework - building agents, tools, dependencies, structured outputs, and model integrations.
Apply shadcn/ui components to React pages and components. This skill should be used when styling specific pages or components with shadcn/ui in a React project that has custom…