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bio-atac-seq-differential-accessibility

Category: Product  ·  Sub-category: prd-spec  ·  Last updated:
Identify differentially accessible chromatin regions across conditions using DiffBind, csaw, DESeq2, or edgeR. Use when comparing ATAC-seq accessibility between treatment groups, choosing between consensus-peak vs sliding-window approaches, picking the correct normalization (full library vs reads-in-peaks), correcting batch with SVA/RUVseq, or interpreting log2FC and FDR thresholds in a chromatin context.

About this skill (catalog notes)

bio-atac-seq-differential-accessibility includes 6 code blocks for direct copy-paste. At roughly 3,122 words the SKILL.md is on the longer end of the catalog distribution.

Source
bg-szy.github.io/TOP-SKILLS
Original author
bg-szy
Indexed lastmod
Catalog position
Product · prd-spec
Indexed related skills
10

How bio-atac-seq-differential-accessibility fits the catalog

bio-atac-seq-differential-accessibility sits in the Product category under the prd-spec sub-topic in the ClaudSkills catalog. There are 10 related skills indexed alongside it; comparing a few before installing usually reveals which fits your workflow best.

These notes are auto-generated from features detected in the SKILL.md file and from this catalog's structure — they aren't part of the source repository.

What this skill does

bio-atac-seq-differential-accessibility is a community-contributed Claude Code skill in the prd-spec sub-category. It ships as a SKILL.md file that Claude Code auto-discovers under ~/.claude/skills/bio-atac-seq-differential-accessibility--skills-differential-acc/ and loads when your prompt matches the skill's trigger.

When to invoke it: Use when comparing ATAC-seq accessibility between treatment groups, choosing between consensus-peak vs sliding-window approaches, picking the correct normalization (full library vs reads-in-peaks), correcting batch with SVA/RUVseq, or interpreting log2FC and FDR thresholds in a chromatin context.

Who uses this skill

The bio-atac-seq-differential-accessibility Claude Code skill is built for product managers, product designers, and cross-functional teams planning, shipping, and measuring product features. It's part of ClaudSkills (also referred to as Claude Skills or Claude Code Skills) — the open community-curated registry of 116,000+ SKILL.md files for Anthropic's Claude Code agent and the wider Claude ecosystem (Claude API, Claude Agent SDK).

How to install

Free

Manual install (2 steps)

mkdir -p ~/.claude/skills/bio-atac-seq-differential-accessibility--skills-differential-acc
curl -L https://claudskills.com/skills/bio-atac-seq-differential-accessibility--skills-differential-acc/SKILL.md \
  -o ~/.claude/skills/bio-atac-seq-differential-accessibility--skills-differential-acc/SKILL.md

Or just download SKILL.md directly and drop it into ~/.claude/skills/bio-atac-seq-differential-accessibility--skills-differential-acc/. Claude Code auto-discovers it on next session.

Skills live at ~/.claude/skills/bio-atac-seq-differential-accessibility--skills-differential-acc/SKILL.md on macOS/Linux, or %USERPROFILE%\.claude\skills\bio-atac-seq-differential-accessibility--skills-differential-acc\SKILL.md on Windows. See the full install guide for step-by-step instructions.

Telegram

📱 Install from your phone or desktop Telegram

Open @claudskills_bot on Telegram, tap Open Desktop App, and the desktop app installs this skill for you. Or share the bot link with a colleague — they get the same one-tap install. Learn more →

Pro

One-click install via the desktop app

The ClaudSkills desktop app installs any skill directly into ~/.claude/skills/ with one click — no terminal required. Pro starts at $9/mo or $149 lifetime.

Pro

For the full experience including quality scoring and one-click install features for each skill — upgrade to Pro.

Frequently asked questions

How do I install the bio-atac-seq-differential-accessibility Claude Code skill?
Install via the ClaudSkills desktop app (one click) or copy SKILL.md from the source repository to ~/.claude/skills/bio-atac-seq-differential-accessibility--skills-differential-acc/SKILL.md and restart Claude Code. Both flows are detailed at claudskills.com/install/.
What does the bio-atac-seq-differential-accessibility skill do?
Identify differentially accessible chromatin regions across conditions using DiffBind, csaw, DESeq2, or edgeR. Use when comparing ATAC-seq accessibility between treatment groups, choosing between consensus-peak vs sliding-window approaches, picking the correct normalization (full library vs reads-in-peaks), correcting batch with SVA/RUVseq, or interpreting log2FC and FDR thresholds in a chromatin context.
Is this skill free to install?
Yes. ClaudSkills is an open registry — every skill keeps its source repository's license, and manual install via copy is free. ClaudSkills Pro ($9/mo, $79/yr, or $149 one-time) adds one-click install via the desktop app and a multi-signal Quality Score.
When should I use the bio-atac-seq-differential-accessibility skill?
Use bio-atac-seq-differential-accessibility when your Claude Code task falls under the Product category — specifically in the prd spec area. Claude Code auto-discovers installed skills and invokes the right one based on the task description, so you can also ask Claude directly (e.g. "use bio-atac-seq-differential-accessibility" or describe the task and let Claude pick). Browse related skills at /category/product/.
What is a Claude Code skill and how does the bio-atac-seq-differential-accessibility skill fit in?
A Claude Code skill is a SKILL.md file that lives under ~/.claude/skills/<name>/ and tells the Claude Code CLI agent how to perform a specific task (instructions, prompts, allowed tools). Skills are auto-discovered at session start. bio-atac-seq-differential-accessibility is one of 67,000+ skills indexed in the open ClaudSkills catalog, classified under the Product category. Learn more at /learn/what-is-a-claude-skill/.

Attribution & license

Cite this skill

If you reference this skill in a blog post, paper, or documentation, you can cite it as:

APA
bg-szy. (2026). bio-atac-seq-differential-accessibility [Claude Code skill]. ClaudSkills. https://claudskills.com/skills/bio-atac-seq-differential-accessibility--skills-differential-acc/
BibTeX
@misc{bio-atac-seq-differential-accessibility--skills-differential-acc-2026,
  author    = {bg-szy},
  title     = {bio-atac-seq-differential-accessibility [Claude Code skill]},
  year      = {2026},
  publisher = {ClaudSkills},
  url       = {https://claudskills.com/skills/bio-atac-seq-differential-accessibility--skills-differential-acc/}
}

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