ClaudSkills / Science & Research / math-stats

Bio Causal Genomics Genetic Correlation

Q: What is a Claude Code skill and how does the Bio Causal Genomics Genetic Correlation skill fit in?

A Claude Code skill is a SKILL.md file that lives under ~/.claude/skills/<name>/ and tells the Claude Code CLI agent how to perform a specific task (instructions, prompts, allowed tools). Skills are auto-discovered at session start. Bio Causal Genomics Genetic Correlation is one of 67,000+ skills indexed in the open ClaudSkills catalog, classified under the Science & Research category. Learn more at https://claudskills.com/learn/what-is-skill-md/.

Category: Science & Research · Sub-category: math-stats · Last updated: 2026-06-02

Estimate bivariate genetic correlation (rg) between traits from GWAS summary statistics or individual-level genotypes using cross-trait LDSC, HDL, LAVA, rho-HESS, GREML-bivariate, Popcorn, and HDL-L. Use when quantifying shared genetic architecture between two traits, screening MR validity before causal inference, distinguishing global from locus-level rg, estimating trans-ancestry rg, separating partial from full causation via LCV gcp, or producing a STROBE-MR-compliant cross-trait sensitivity battery. Cross-trait LDSC intercept absorbs sample overlap and is NOT a bias; HDL is biased under sample overlap above ~5%. High rg between exposure and outcome motivates CHP-aware MR sensitivity (CAUSE, LHC-MR).

What this skill does

Bio Causal Genomics Genetic Correlation is a community-contributed Claude Code skill in the math-stats sub-category. It ships as a SKILL.md file that Claude Code auto-discovers under ~/.claude/skills/bio-causal-genomics-genetic-correlation/ and loads when your prompt matches the skill's trigger.

When to invoke it: Use when quantifying shared genetic architecture between two traits, screening MR validity before causal inference, distinguishing global from locus-level rg, estimating trans-ancestry rg, separating partial from full causation via LCV gcp, or producing a STROBE-MR-compliant cross-trait sensitivity battery. Cross-trait LDSC intercept absorbs sample overlap and is NOT a bias; HDL is biased under sample overlap above ~5%.

Who uses this skill

The Bio Causal Genomics Genetic Correlation Claude Code skill is built for researchers, data scientists, academics, and analysts working with complex data and scientific literature. It's part of ClaudSkills (also referred to as Claude Skills or Claude Code Skills) — the open community-curated registry of 93,000+ SKILL.md files for Anthropic's Claude Code agent and the wider Claude ecosystem (Claude API, Claude Agent SDK).

How to install

Free

Manual install (2 steps)

mkdir -p ~/.claude/skills/bio-causal-genomics-genetic-correlation
curl -L https://claudskills.com/skills/bio-causal-genomics-genetic-correlation/SKILL.md \
  -o ~/.claude/skills/bio-causal-genomics-genetic-correlation/SKILL.md

Or just download SKILL.md directly and drop it into ~/.claude/skills/bio-causal-genomics-genetic-correlation/. Claude Code auto-discovers it on next session.

Skills live at ~/.claude/skills/bio-causal-genomics-genetic-correlation/SKILL.md on macOS/Linux, or %USERPROFILE%\.claude\skills\bio-causal-genomics-genetic-correlation\SKILL.md on Windows. See the full install guide for step-by-step instructions.

📱 Install from your phone or desktop Telegram

Open @claudskills_bot on Telegram, tap Open Desktop App, and the desktop app installs this skill for you. Or share the bot link with a colleague — they get the same one-tap install. Learn more →

Pro

One-click install via the desktop app

The ClaudSkills desktop app installs any skill directly into ~/.claude/skills/ with one click — no terminal required. Pro starts at $9/mo or $149 lifetime.

Pro

For the full experience including quality scoring and one-click install features for each skill — upgrade to Pro.

See pricing → Download desktop app

Frequently asked questions

How do I install the Bio Causal Genomics Genetic Correlation Claude Code skill?

Install via the ClaudSkills desktop app (one click) or copy SKILL.md from the source repository to ~/.claude/skills/bio-causal-genomics-genetic-correlation/SKILL.md and restart Claude Code. Both flows are detailed at claudskills.com/install/.

What does the Bio Causal Genomics Genetic Correlation skill do?

Is this skill free to install?

Yes. ClaudSkills is an open registry — every skill keeps its source repository's license, and manual install via copy is free. ClaudSkills Pro ($9/mo, $79/yr, or $149 one-time) adds one-click install via the desktop app and a multi-signal Quality Score.

When should I use the Bio Causal Genomics Genetic Correlation skill?

Use Bio Causal Genomics Genetic Correlation when your Claude Code task falls under the Science & Research category — specifically in the math stats area. Claude Code auto-discovers installed skills and invokes the right one based on the task description, so you can also ask Claude directly (e.g. "use Bio Causal Genomics Genetic Correlation" or describe the task and let Claude pick). Browse related skills at /category/science/.

What is a Claude Code skill and how does the Bio Causal Genomics Genetic Correlation skill fit in?

A Claude Code skill is a SKILL.md file that lives under ~/.claude/skills/<name>/ and tells the Claude Code CLI agent how to perform a specific task (instructions, prompts, allowed tools). Skills are auto-discovered at session start. Bio Causal Genomics Genetic Correlation is one of 67,000+ skills indexed in the open ClaudSkills catalog, classified under the Science & Research category. Learn more at /learn/what-is-a-claude-skill/.

Attribution & license

Source: https://github.com/bg-szy/TOP-SKILLS/blob/HEAD/skills/awesome-skills/bio-causal-genomics-genetic-correlation/SKILL.md
Author: bg-szy
Website: https://bg-szy.github.io/TOP-SKILLS/

Cite this skill

If you reference this skill in a blog post, paper, or documentation, you can cite it as:

APA

bg-szy. (2026). Bio Causal Genomics Genetic Correlation [Claude Code skill]. ClaudSkills. https://claudskills.com/skills/bio-causal-genomics-genetic-correlation/

BibTeX

@misc{bio-causal-genomics-genetic-correlation-2026,
  author    = {bg-szy},
  title     = {Bio Causal Genomics Genetic Correlation [Claude Code skill]},
  year      = {2026},
  publisher = {ClaudSkills},
  url       = {https://claudskills.com/skills/bio-causal-genomics-genetic-correlation/}
}

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