bio-chipseq-peak-annotation
Annotates ChIP-seq peaks to genomic features, nearest genes, ENCODE candidate cis-regulatory elements (cCREs), and regulatory domains. Uses ChIPseeker (R), HOMER annotatePeaks.pl (CLI), pyranges (Python), GREAT/rGREAT (regulatory domain gene-set enrichment), ChIP-Enrich (locus-length-adjusted), ENCODE SCREEN cCRE classification (PLS/pELS/dELS/CTCF-only/DNase-H3K4me3), and ENCODE-rE2G for cell-type-specific enhancer-gene linking. Handles nearest-TSS vs host-gene ambiguity, promoter window definition, and feature priority. Use when assigning genomic context to peaks, linking enhancer peaks to target genes, classifying peaks against ENCODE cCRE registry, or running gene-set enrichment on peak-associated genes.
What this skill does
bio-chipseq-peak-annotation is a community-contributed Claude Code skill in the backend sub-category. It ships as a SKILL.md file that Claude Code auto-discovers under ~/.claude/skills/bio-chipseq-peak-annotation--skills-peak-annotation/ and loads when your prompt matches the skill's trigger.
When to invoke it: Use when assigning genomic context to peaks, linking enhancer peaks to target genes, classifying peaks against ENCODE cCRE registry, or running gene-set enrichment on peak-associated genes.
Who uses this skill
The bio-chipseq-peak-annotation Claude Code skill is built for software engineers, backend developers, full-stack teams, and technical leads building and maintaining production systems. It's part of ClaudSkills (also referred to as Claude Skills or Claude Code Skills) — the open community-curated registry of 93,000+ SKILL.md files for Anthropic's Claude Code agent and the wider Claude ecosystem (Claude API, Claude Agent SDK).
How to install
Free
Manual install (2 steps)
mkdir -p ~/.claude/skills/bio-chipseq-peak-annotation--skills-peak-annotation
curl -L https://claudskills.com/skills/bio-chipseq-peak-annotation--skills-peak-annotation/SKILL.md \
-o ~/.claude/skills/bio-chipseq-peak-annotation--skills-peak-annotation/SKILL.md
Or just download SKILL.md directly and drop it into ~/.claude/skills/bio-chipseq-peak-annotation--skills-peak-annotation/. Claude Code auto-discovers it on next session.
Skills live at ~/.claude/skills/bio-chipseq-peak-annotation--skills-peak-annotation/SKILL.md on macOS/Linux, or %USERPROFILE%\.claude\skills\bio-chipseq-peak-annotation--skills-peak-annotation\SKILL.md on Windows. See the full install guide for step-by-step instructions.
Telegram
📱 Install from your phone or desktop Telegram
Open @claudskills_bot on Telegram, tap Open Desktop App, and the desktop app installs this skill for you. Or share the bot link with a colleague — they get the same one-tap install. Learn more →
Pro
One-click install via the desktop app
The ClaudSkills desktop app installs any skill directly into ~/.claude/skills/ with one click — no terminal required. Pro starts at $9/mo or $149 lifetime.
Pro
For the full experience including quality scoring and one-click install features for each skill — upgrade to Pro.
Frequently asked questions
How do I install the bio-chipseq-peak-annotation Claude Code skill?
Install via the ClaudSkills desktop app (one click) or copy
SKILL.md from the source repository to
~/.claude/skills/bio-chipseq-peak-annotation--skills-peak-annotation/SKILL.md and restart Claude Code. Both flows are detailed at
claudskills.com/install/.
What does the bio-chipseq-peak-annotation skill do?
Annotates ChIP-seq peaks to genomic features, nearest genes, ENCODE candidate cis-regulatory elements (cCREs), and regulatory domains. Uses ChIPseeker (R), HOMER annotatePeaks.pl (CLI), pyranges (Python), GREAT/rGREAT (regulatory domain gene-set enrichment), ChIP-Enrich (locus-length-adjusted), ENCODE SCREEN cCRE classification (PLS/pELS/dELS/CTCF-only/DNase-H3K4me3), and ENCODE-rE2G for cell-type-specific enhancer-gene linking. Handles nearest-TSS vs host-gene ambiguity, promoter window definition, and feature priority. Use when assigning genomic context to peaks, linking enhancer peaks to target genes, classifying peaks against ENCODE cCRE registry, or running gene-set enrichment on peak-associated genes.
Is this skill free to install?
Yes. ClaudSkills is an open registry — every skill keeps its source repository's license, and manual install via copy is free. ClaudSkills Pro ($9/mo, $79/yr, or $149 one-time) adds one-click install via the desktop app and a multi-signal Quality Score.
When should I use the bio-chipseq-peak-annotation skill?
Use bio-chipseq-peak-annotation when your Claude Code task falls under the Engineering category — specifically in the backend area. Claude Code auto-discovers installed skills and invokes the right one based on the task description, so you can also ask Claude directly (e.g. "use bio-chipseq-peak-annotation" or describe the task and let Claude pick). Browse related skills at
/category/engineering/.
What is a Claude Code skill and how does the bio-chipseq-peak-annotation skill fit in?
A Claude Code skill is a
SKILL.md file that lives under
~/.claude/skills/<name>/ and tells the Claude Code CLI agent how to perform a specific task (instructions, prompts, allowed tools). Skills are auto-discovered at session start. bio-chipseq-peak-annotation is one of 67,000+ skills indexed in the open ClaudSkills catalog, classified under the Engineering category. Learn more at
/learn/what-is-a-claude-skill/.
Attribution & license
Cite this skill
If you reference this skill in a blog post, paper, or documentation, you can cite it as:
APA
bg-szy. (2026). bio-chipseq-peak-annotation [Claude Code skill]. ClaudSkills. https://claudskills.com/skills/bio-chipseq-peak-annotation--skills-peak-annotation/
BibTeX
@misc{bio-chipseq-peak-annotation--skills-peak-annotation-2026,
author = {bg-szy},
title = {bio-chipseq-peak-annotation [Claude Code skill]},
year = {2026},
publisher = {ClaudSkills},
url = {https://claudskills.com/skills/bio-chipseq-peak-annotation--skills-peak-annotation/}
}
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