Quantifies CRISPR editing outcomes with CRISPResso2 (Clement 2019 Nat Biotechnol) across Cas9-nuclease (indels, HDR), CBE and ABE base editors (target conversion + bystander), and prime editor (pegRNA-templated) modes. Covers single-amplicon (CRISPResso), multi-sample batch (CRISPRessoBatch), pooled-amplicon (CRISPRessoPooled), WGS off-target (CRISPRessoWGS), and sample-comparison (CRISPRessoCompare) workflows; quantification-window math that controls what is called edited; substitution-vs-indel diagnostic to distinguish BE from Cas9 contamination; MMEJ deletion pattern interpretation; allele-frequency tables; and failure modes from amplicon misalignment or contamination. Use when quantifying editing from amplicon sequencing, choosing CRISPResso mode by design, distinguishing intended edits from bystanders and indel byproducts, debugging low-alignment runs, or generating publication-grade editing reports.
About this skill (catalog notes)
bio-crispr-screens-crispresso-editing includes worked examples; 8 code blocks for direct copy-paste. At roughly 2,217 words the SKILL.md is on the longer end of the catalog distribution.
How bio-crispr-screens-crispresso-editing fits the catalog
bio-crispr-screens-crispresso-editing sits in the Growth & Marketing category under the conversion sub-topic in the ClaudSkills catalog. There are 10 related skills indexed alongside it; comparing a few before installing usually reveals which fits your workflow best.
These notes are auto-generated from features detected in the SKILL.md file and from this catalog's structure — they aren't part of the source repository.
What this skill does
bio-crispr-screens-crispresso-editing is a community-contributed Claude Code skill in the conversion sub-category. It ships as a SKILL.md file that Claude Code auto-discovers under ~/.claude/skills/bio-crispr-screens-crispresso-editing--skills-crispresso-editing/ and loads when your prompt matches the skill's trigger.
When to invoke it: Use when quantifying editing from amplicon sequencing, choosing CRISPResso mode by design, distinguishing intended edits from bystanders and indel byproducts, debugging low-alignment runs, or generating publication-grade editing reports.
Who uses this skill
The bio-crispr-screens-crispresso-editing Claude Code skill is built for growth marketers, product-led growth teams, founders running experiments, and performance marketing teams. It's part of ClaudSkills (also referred to as Claude Skills or Claude Code Skills) — the open community-curated registry of 116,000+ SKILL.md files for Anthropic's Claude Code agent and the wider Claude ecosystem (Claude API, Claude Agent SDK).
Or just download SKILL.md directly and drop it into ~/.claude/skills/bio-crispr-screens-crispresso-editing--skills-crispresso-editing/. Claude Code auto-discovers it on next session.
Skills live at ~/.claude/skills/bio-crispr-screens-crispresso-editing--skills-crispresso-editing/SKILL.md on macOS/Linux, or %USERPROFILE%\.claude\skills\bio-crispr-screens-crispresso-editing--skills-crispresso-editing\SKILL.md on Windows. See the full install guide for step-by-step instructions.
Telegram
📱 Install from your phone or desktop Telegram
Open @claudskills_bot on Telegram, tap Open Desktop App, and the desktop app installs this skill for you. Or share the bot link with a colleague — they get the same one-tap install. Learn more →
Pro
One-click install via the desktop app
The ClaudSkills desktop app installs any skill directly into ~/.claude/skills/ with one click — no terminal required. Pro starts at $9/mo or $149 lifetime.
Pro
For the full experience including quality scoring and one-click install features for each skill — upgrade to Pro.
How do I install the bio-crispr-screens-crispresso-editing Claude Code skill?
Install via the ClaudSkills desktop app (one click) or copy SKILL.md from the source repository to ~/.claude/skills/bio-crispr-screens-crispresso-editing--skills-crispresso-editing/SKILL.md and restart Claude Code. Both flows are detailed at claudskills.com/install/.
What does the bio-crispr-screens-crispresso-editing skill do?
Quantifies CRISPR editing outcomes with CRISPResso2 (Clement 2019 Nat Biotechnol) across Cas9-nuclease (indels, HDR), CBE and ABE base editors (target conversion + bystander), and prime editor (pegRNA-templated) modes. Covers single-amplicon (CRISPResso), multi-sample batch (CRISPRessoBatch), pooled-amplicon (CRISPRessoPooled), WGS off-target (CRISPRessoWGS), and sample-comparison (CRISPRessoCompare) workflows; quantification-window math that controls what is called edited; substitution-vs-indel diagnostic to distinguish BE from Cas9 contamination; MMEJ deletion pattern interpretation; allele-frequency tables; and failure modes from amplicon misalignment or contamination. Use when quantifying editing from amplicon sequencing, choosing CRISPResso mode by design, distinguishing intended edits from bystanders and indel byproducts, debugging low-alignment runs, or generating publication-grade editing reports.
Is this skill free to install?
Yes. ClaudSkills is an open registry — every skill keeps its source repository's license, and manual install via copy is free. ClaudSkills Pro ($9/mo, $79/yr, or $149 one-time) adds one-click install via the desktop app and a multi-signal Quality Score.
When should I use the bio-crispr-screens-crispresso-editing skill?
Use bio-crispr-screens-crispresso-editing when your Claude Code task falls under the Growth & Marketing category — specifically in the conversion area. Claude Code auto-discovers installed skills and invokes the right one based on the task description, so you can also ask Claude directly (e.g. "use bio-crispr-screens-crispresso-editing" or describe the task and let Claude pick). Browse related skills at /category/growth/.
What is a Claude Code skill and how does the bio-crispr-screens-crispresso-editing skill fit in?
A Claude Code skill is a SKILL.md file that lives under ~/.claude/skills/<name>/ and tells the Claude Code CLI agent how to perform a specific task (instructions, prompts, allowed tools). Skills are auto-discovered at session start. bio-crispr-screens-crispresso-editing is one of 67,000+ skills indexed in the open ClaudSkills catalog, classified under the Growth & Marketing category. Learn more at /learn/what-is-a-claude-skill/.
@misc{bio-crispr-screens-crispresso-editing--skills-crispresso-editing-2026,
author = {bg-szy},
title = {bio-crispr-screens-crispresso-editing [Claude Code skill]},
year = {2026},
publisher = {ClaudSkills},
url = {https://claudskills.com/skills/bio-crispr-screens-crispresso-editing--skills-crispresso-editing/}
}
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Claude™ is a trademark of Anthropic PBC. ClaudSkills (also referred to as Claude Skills or Claude Code Skills Catalog) is an independent community-curated registry of SKILL.md files, not affiliated with, endorsed by, or sponsored by Anthropic.
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