bio-crispr-screens-screen-qc

Q: What is a Claude Code skill and how does the bio-crispr-screens-screen-qc skill fit in?

A Claude Code skill is a SKILL.md file that lives under ~/.claude/skills/<name>/ and tells the Claude Code CLI agent how to perform a specific task (instructions, prompts, allowed tools). Skills are auto-discovered at session start. bio-crispr-screens-screen-qc is one of 67,000+ skills indexed in the open ClaudSkills catalog, classified under the Content category. Learn more at https://claudskills.com/learn/what-is-skill-md/.

Category: Content · Sub-category: content-misc · Last updated: 2026-06-02

lang:python type:debug

Quality control for pooled CRISPR screens covering library representation, Gini index, log-skew, replicate Pearson and Spearman concordance, essentialome precision-recall AUC against CEGv2 (Hart 2017), Cas9 cut-toxicity diagnostics, copy-number amplicon detection (Aguirre 2016 / Munoz 2016), bottleneck propagation through plasmid pool, infection, selection, and endpoint stages, MOI verification, and DepMap-style screen-quality scoring. Use when assessing screen quality before hit calling, deciding whether to repeat or rescue a screen, diagnosing low-confidence hits, choosing between MAGeCK / BAGEL2 / Chronos based on quality grade, picking a normalization strategy from QC signatures, or evaluating whether an in-vivo screen retained adequate library complexity.

Security AStatic scan found no risk patternsHow grading works ›

What this skill does

bio-crispr-screens-screen-qc is a community-contributed Claude Code skill in the content-misc sub-category. It ships as a SKILL.md file that Claude Code auto-discovers under ~/.claude/skills/bio-crispr-screens-screen-qc--skills-screen-qc/ and loads when your prompt matches the skill's trigger.

When to invoke it: Use when assessing screen quality before hit calling, deciding whether to repeat or rescue a screen, diagnosing low-confidence hits, choosing between MAGeCK / BAGEL2 / Chronos based on quality grade, picking a normalization strategy from QC signatures, or evaluating whether an in-vivo screen retained adequate library complexity.

Who uses this skill

The bio-crispr-screens-screen-qc Claude Code skill is built for content creators, marketers, copywriters, SEO professionals, and editorial teams. It's part of ClaudSkills (also referred to as Claude Skills or Claude Code Skills) — the open community-curated registry of 115,000+ SKILL.md files for Anthropic's Claude Code agent and the wider Claude ecosystem (Claude API, Claude Agent SDK).

How to install

Free

Manual install (2 steps)

mkdir -p ~/.claude/skills/bio-crispr-screens-screen-qc--skills-screen-qc
curl -L https://claudskills.com/skills/bio-crispr-screens-screen-qc--skills-screen-qc/SKILL.md \
  -o ~/.claude/skills/bio-crispr-screens-screen-qc--skills-screen-qc/SKILL.md

Or just download SKILL.md directly and drop it into ~/.claude/skills/bio-crispr-screens-screen-qc--skills-screen-qc/. Claude Code auto-discovers it on next session.

Skills live at ~/.claude/skills/bio-crispr-screens-screen-qc--skills-screen-qc/SKILL.md on macOS/Linux, or %USERPROFILE%\.claude\skills\bio-crispr-screens-screen-qc--skills-screen-qc\SKILL.md on Windows. See the full install guide for step-by-step instructions.

📱 Install from your phone or desktop Telegram

Open @claudskills_bot on Telegram, tap Open Desktop App, and the desktop app installs this skill for you. Or share the bot link with a colleague — they get the same one-tap install. Learn more →

Pro

One-click install via the desktop app

The ClaudSkills desktop app installs any skill directly into ~/.claude/skills/ with one click — no terminal required. Pro starts at $9/mo or $149 lifetime.

Pro

For the full experience including quality scoring and one-click install features for each skill — upgrade to Pro.

See pricing → Download desktop app

Frequently asked questions

How do I install the bio-crispr-screens-screen-qc Claude Code skill?

Install via the ClaudSkills desktop app (one click) or copy SKILL.md from the source repository to ~/.claude/skills/bio-crispr-screens-screen-qc--skills-screen-qc/SKILL.md and restart Claude Code. Both flows are detailed at claudskills.com/install/.

What does the bio-crispr-screens-screen-qc skill do?

Is this skill free to install?

Yes. ClaudSkills is an open registry — every skill keeps its source repository's license, and manual install via copy is free. ClaudSkills Pro ($9/mo, $79/yr, or $149 one-time) adds one-click install via the desktop app and a multi-signal Quality Score.

When should I use the bio-crispr-screens-screen-qc skill?

Use bio-crispr-screens-screen-qc when your Claude Code task falls under the Content category — specifically in the content misc area. Claude Code auto-discovers installed skills and invokes the right one based on the task description, so you can also ask Claude directly (e.g. "use bio-crispr-screens-screen-qc" or describe the task and let Claude pick). Browse related skills at /category/content/.

What is a Claude Code skill and how does the bio-crispr-screens-screen-qc skill fit in?

A Claude Code skill is a SKILL.md file that lives under ~/.claude/skills/<name>/ and tells the Claude Code CLI agent how to perform a specific task (instructions, prompts, allowed tools). Skills are auto-discovered at session start. bio-crispr-screens-screen-qc is one of 67,000+ skills indexed in the open ClaudSkills catalog, classified under the Content category. Learn more at /learn/what-is-a-claude-skill/.

Attribution & license

Source: https://github.com/bg-szy/TOP-SKILLS/blob/HEAD/skills/awesome-skills/bio-crispr-screens-screen-qc__skills-screen-qc/SKILL.md
Author: bg-szy
Website: https://bg-szy.github.io/TOP-SKILLS/

Cite this skill

If you reference this skill in a blog post, paper, or documentation, you can cite it as:

APA

bg-szy. (2026). bio-crispr-screens-screen-qc [Claude Code skill]. ClaudSkills. https://claudskills.com/skills/bio-crispr-screens-screen-qc--skills-screen-qc/

BibTeX

@misc{bio-crispr-screens-screen-qc--skills-screen-qc-2026,
  author    = {bg-szy},
  title     = {bio-crispr-screens-screen-qc [Claude Code skill]},
  year      = {2026},
  publisher = {ClaudSkills},
  url       = {https://claudskills.com/skills/bio-crispr-screens-screen-qc--skills-screen-qc/}
}

Embed this skill

Promote, attribute, or link this skill from your own README, blog post, or documentation. All three snippets are free to use — no sign-up, no API key. More distribution surfaces →

Badge

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Security scan

Grade A · scanned 2026-06-13 — free static scan against the OWASP Agentic Skills Top 10.

No risk patterns were found in any of the ten OWASP-aligned categories. How grading works ›

✓ Prompt injection
✓ Data exfiltration
✓ Supply chain
✓ Reverse shell
✓ Credentials
✓ Execution
✓ Filesystem
✓ Persistence
✓ Obfuscation
✓ Network

Show this grade on your repo (click to copy):

[![Security: A](https://img.shields.io/badge/Security-A-2e7d32)](https://claudskills.com/skills/bio-crispr-screens-screen-qc--skills-screen-qc/#security)