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bio-epitranscriptomics-m6anet-analysis

Category: Content  ·  Sub-category: content-misc  ·  Last updated:
Detects m6A modifications from Oxford Nanopore direct-RNA-sequencing (ONT DRS) signal data using m6Anet (Hendra 2022 *Nat Methods* 19:1590; multiple-instance-learning neural network over DRACH 5-mer signal). Covers the required upstream pipeline (Dorado / Guppy basecalling -> minimap2 transcriptome alignment with `-ax map-ont -uf -k14 --secondary=no` -> nanopolish eventalign with `--scale-events --signal-index` (m6Anet-required) plus `--summary` / `--threads` housekeeping -> m6anet dataprep -> m6anet inference), per-site vs per-read probability interpretation including the `mod_ratio` per-site stoichiometry column, the DRACH-only modeling constraint, minimum-coverage thresholds (20-50 reads per site for stable probability estimates), multi-condition comparison via xPore (Pratanwanich 2021 *Nat Biotechnol* 39:1394), Nanocompore (Leger 2021 *Nat Commun* 12:7198), ELIGOS (Jenjaroenpun 2021 *NAR* 49:e7), and Dorado native modification calling (RNA004 chemistry, 2024+), reference-transcriptome version...
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About this skill (catalog notes)

bio-epitranscriptomics-m6anet-analysis includes at least one code block. At roughly 4,627 words the SKILL.md is on the longer end of the catalog distribution.

Source
bg-szy.github.io/TOP-SKILLS
Original author
bg-szy
Indexed lastmod
Catalog position
Content · content-misc
Indexed related skills
10

How bio-epitranscriptomics-m6anet-analysis fits the catalog

bio-epitranscriptomics-m6anet-analysis sits in the Content category under the content-misc sub-topic in the ClaudSkills catalog. There are 10 related skills indexed alongside it; comparing a few before installing usually reveals which fits your workflow best.

These notes are auto-generated from features detected in the SKILL.md file and from this catalog's structure — they aren't part of the source repository.

What this skill does

bio-epitranscriptomics-m6anet-analysis is a community-contributed Claude Code skill in the content-misc sub-category. It ships as a SKILL.md file that Claude Code auto-discovers under ~/.claude/skills/bio-epitranscriptomics-m6anet-analysis--skills-m6anet-analysis/ and loads when your prompt matches the skill's trigger.

Who uses this skill

The bio-epitranscriptomics-m6anet-analysis Claude Code skill is built for content creators, marketers, copywriters, SEO professionals, and editorial teams. It's part of ClaudSkills (also referred to as Claude Skills or Claude Code Skills) — the open community-curated registry of 115,000+ SKILL.md files for Anthropic's Claude Code agent and the wider Claude ecosystem (Claude API, Claude Agent SDK).

How to install

Free

Manual install (2 steps)

mkdir -p ~/.claude/skills/bio-epitranscriptomics-m6anet-analysis--skills-m6anet-analysis
curl -L https://claudskills.com/skills/bio-epitranscriptomics-m6anet-analysis--skills-m6anet-analysis/SKILL.md \
  -o ~/.claude/skills/bio-epitranscriptomics-m6anet-analysis--skills-m6anet-analysis/SKILL.md

Or just download SKILL.md directly and drop it into ~/.claude/skills/bio-epitranscriptomics-m6anet-analysis--skills-m6anet-analysis/. Claude Code auto-discovers it on next session.

Skills live at ~/.claude/skills/bio-epitranscriptomics-m6anet-analysis--skills-m6anet-analysis/SKILL.md on macOS/Linux, or %USERPROFILE%\.claude\skills\bio-epitranscriptomics-m6anet-analysis--skills-m6anet-analysis\SKILL.md on Windows. See the full install guide for step-by-step instructions.

Telegram

📱 Install from your phone or desktop Telegram

Open @claudskills_bot on Telegram, tap Open Desktop App, and the desktop app installs this skill for you. Or share the bot link with a colleague — they get the same one-tap install. Learn more →

Pro

One-click install via the desktop app

The ClaudSkills desktop app installs any skill directly into ~/.claude/skills/ with one click — no terminal required. Pro starts at $9/mo or $149 lifetime.

Pro

For the full experience including quality scoring and one-click install features for each skill — upgrade to Pro.

Frequently asked questions

How do I install the bio-epitranscriptomics-m6anet-analysis Claude Code skill?
Install via the ClaudSkills desktop app (one click) or copy SKILL.md from the source repository to ~/.claude/skills/bio-epitranscriptomics-m6anet-analysis--skills-m6anet-analysis/SKILL.md and restart Claude Code. Both flows are detailed at claudskills.com/install/.
What does the bio-epitranscriptomics-m6anet-analysis skill do?
Detects m6A modifications from Oxford Nanopore direct-RNA-sequencing (ONT DRS) signal data using m6Anet (Hendra 2022 *Nat Methods* 19:1590; multiple-instance-learning neural network over DRACH 5-mer signal). Covers the required upstream pipeline (Dorado / Guppy basecalling -> minimap2 transcriptome alignment with `-ax map-ont -uf -k14 --secondary=no` -> nanopolish eventalign with `--scale-events --signal-index` (m6Anet-required) plus `--summary` / `--threads` housekeeping -> m6anet dataprep -> m6anet inference), per-site vs per-read probability interpretation including the `mod_ratio` per-site stoichiometry column, the DRACH-only modeling constraint, minimum-coverage thresholds (20-50 reads per site for stable probability estimates), multi-condition comparison via xPore (Pratanwanich 2021 *Nat Biotechnol* 39:1394), Nanocompore (Leger 2021 *Nat Commun* 12:7198), ELIGOS (Jenjaroenpun 2021 *NAR* 49:e7), and Dorado native modification calling (RNA004 chemistry, 2024+), reference-transcriptome version...
Is this skill free to install?
Yes. ClaudSkills is an open registry — every skill keeps its source repository's license, and manual install via copy is free. ClaudSkills Pro ($9/mo, $79/yr, or $149 one-time) adds one-click install via the desktop app and a multi-signal Quality Score.
When should I use the bio-epitranscriptomics-m6anet-analysis skill?
Use bio-epitranscriptomics-m6anet-analysis when your Claude Code task falls under the Content category — specifically in the content misc area. Claude Code auto-discovers installed skills and invokes the right one based on the task description, so you can also ask Claude directly (e.g. "use bio-epitranscriptomics-m6anet-analysis" or describe the task and let Claude pick). Browse related skills at /category/content/.
What is a Claude Code skill and how does the bio-epitranscriptomics-m6anet-analysis skill fit in?
A Claude Code skill is a SKILL.md file that lives under ~/.claude/skills/<name>/ and tells the Claude Code CLI agent how to perform a specific task (instructions, prompts, allowed tools). Skills are auto-discovered at session start. bio-epitranscriptomics-m6anet-analysis is one of 67,000+ skills indexed in the open ClaudSkills catalog, classified under the Content category. Learn more at /learn/what-is-a-claude-skill/.

Attribution & license

Cite this skill

If you reference this skill in a blog post, paper, or documentation, you can cite it as:

APA
bg-szy. (2026). bio-epitranscriptomics-m6anet-analysis [Claude Code skill]. ClaudSkills. https://claudskills.com/skills/bio-epitranscriptomics-m6anet-analysis--skills-m6anet-analysis/
BibTeX
@misc{bio-epitranscriptomics-m6anet-analysis--skills-m6anet-analysis-2026,
  author    = {bg-szy},
  title     = {bio-epitranscriptomics-m6anet-analysis [Claude Code skill]},
  year      = {2026},
  publisher = {ClaudSkills},
  url       = {https://claudskills.com/skills/bio-epitranscriptomics-m6anet-analysis--skills-m6anet-analysis/}
}

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