bio-epitranscriptomics-m6anet-analysis
Detects m6A modifications from Oxford Nanopore direct-RNA-sequencing (ONT DRS) signal data using m6Anet (Hendra 2022 *Nat Methods* 19:1590; multiple-instance-learning neural network over DRACH 5-mer signal). Covers the required upstream pipeline (Dorado / Guppy basecalling -> minimap2 transcriptome alignment with `-ax map-ont -uf -k14 --secondary=no` -> nanopolish eventalign with `--scale-events --signal-index` (m6Anet-required) plus `--summary` / `--threads` housekeeping -> m6anet dataprep -> m6anet inference), per-site vs per-read probability interpretation including the `mod_ratio` per-site stoichiometry column, the DRACH-only modeling constraint, minimum-coverage thresholds (20-50 reads per site for stable probability estimates), multi-condition comparison via xPore (Pratanwanich 2021 *Nat Biotechnol* 39:1394), Nanocompore (Leger 2021 *Nat Commun* 12:7198), ELIGOS (Jenjaroenpun 2021 *NAR* 49:e7), and Dorado native modification calling (RNA004 chemistry, 2024+), reference-transcriptome version...
Security AStatic scan found no risk patternsHow grading works ›
What this skill does
bio-epitranscriptomics-m6anet-analysis is a community-contributed Claude Code skill in the content-misc sub-category. It ships as a SKILL.md file that Claude Code auto-discovers under ~/.claude/skills/bio-epitranscriptomics-m6anet-analysis--skills-m6anet-analysis/ and loads when your prompt matches the skill's trigger.
Who uses this skill
The bio-epitranscriptomics-m6anet-analysis Claude Code skill is built for content creators, marketers, copywriters, SEO professionals, and editorial teams. It's part of ClaudSkills (also referred to as Claude Skills or Claude Code Skills) — the open community-curated registry of 178,000+ SKILL.md files for Anthropic's Claude Code agent and the wider Claude ecosystem (Claude API, Claude Agent SDK).
How to install
Free
Manual install (2 steps)
mkdir -p ~/.claude/skills/bio-epitranscriptomics-m6anet-analysis--skills-m6anet-analysis
curl -L https://claudskills.com/skills/bio-epitranscriptomics-m6anet-analysis--skills-m6anet-analysis/SKILL.md \
-o ~/.claude/skills/bio-epitranscriptomics-m6anet-analysis--skills-m6anet-analysis/SKILL.md
Or just download SKILL.md directly and drop it into ~/.claude/skills/bio-epitranscriptomics-m6anet-analysis--skills-m6anet-analysis/. Claude Code auto-discovers it on next session.
Skills live at ~/.claude/skills/bio-epitranscriptomics-m6anet-analysis--skills-m6anet-analysis/SKILL.md on macOS/Linux, or %USERPROFILE%\.claude\skills\bio-epitranscriptomics-m6anet-analysis--skills-m6anet-analysis\SKILL.md on Windows. See the full install guide for step-by-step instructions.
Telegram
📱 Install from your phone or desktop Telegram
Open @claudskills_bot on Telegram, tap Open Desktop App, and the desktop app installs this skill for you. Or share the bot link with a colleague — they get the same one-tap install. Learn more →
Pro
One-click install via the desktop app
The ClaudSkills desktop app installs any skill directly into ~/.claude/skills/ with one click — no terminal required. Pro starts at $9/mo or $149 lifetime.
Pro
For the full experience including quality scoring and one-click install features for each skill — upgrade to Pro.
Frequently asked questions
How do I install the bio-epitranscriptomics-m6anet-analysis Claude Code skill?
Install via the ClaudSkills desktop app (one click) or copy
SKILL.md from the source repository to
~/.claude/skills/bio-epitranscriptomics-m6anet-analysis--skills-m6anet-analysis/SKILL.md and restart Claude Code. Both flows are detailed at
claudskills.com/install/.
What does the bio-epitranscriptomics-m6anet-analysis skill do?
Detects m6A modifications from Oxford Nanopore direct-RNA-sequencing (ONT DRS) signal data using m6Anet (Hendra 2022 *Nat Methods* 19:1590; multiple-instance-learning neural network over DRACH 5-mer signal). Covers the required upstream pipeline (Dorado / Guppy basecalling -> minimap2 transcriptome alignment with `-ax map-ont -uf -k14 --secondary=no` -> nanopolish eventalign with `--scale-events --signal-index` (m6Anet-required) plus `--summary` / `--threads` housekeeping -> m6anet dataprep -> m6anet inference), per-site vs per-read probability interpretation including the `mod_ratio` per-site stoichiometry column, the DRACH-only modeling constraint, minimum-coverage thresholds (20-50 reads per site for stable probability estimates), multi-condition comparison via xPore (Pratanwanich 2021 *Nat Biotechnol* 39:1394), Nanocompore (Leger 2021 *Nat Commun* 12:7198), ELIGOS (Jenjaroenpun 2021 *NAR* 49:e7), and Dorado native modification calling (RNA004 chemistry, 2024+), reference-transcriptome version...
Is this skill free to install?
Yes. ClaudSkills is an open registry — every skill keeps its source repository's license, and manual install via copy is free. ClaudSkills Pro ($9/mo, $79/yr, or $149 one-time) adds one-click install via the desktop app and a multi-signal Quality Score.
When should I use the bio-epitranscriptomics-m6anet-analysis skill?
Use bio-epitranscriptomics-m6anet-analysis when your Claude Code task falls under the Content category — specifically in the content misc area. Claude Code auto-discovers installed skills and invokes the right one based on the task description, so you can also ask Claude directly (e.g. "use bio-epitranscriptomics-m6anet-analysis" or describe the task and let Claude pick). Browse related skills at
/category/content/.
What is a Claude Code skill and how does the bio-epitranscriptomics-m6anet-analysis skill fit in?
A Claude Code skill is a
SKILL.md file that lives under
~/.claude/skills/<name>/ and tells the Claude Code CLI agent how to perform a specific task (instructions, prompts, allowed tools). Skills are auto-discovered at session start. bio-epitranscriptomics-m6anet-analysis is one of 67,000+ skills indexed in the open ClaudSkills catalog, classified under the Content category. Learn more at
/learn/what-is-a-claude-skill/.
Attribution & license
Cite this skill
If you reference this skill in a blog post, paper, or documentation, you can cite it as:
APA
bg-szy. (2026). bio-epitranscriptomics-m6anet-analysis [Claude Code skill]. ClaudSkills. https://claudskills.com/skills/bio-epitranscriptomics-m6anet-analysis--skills-m6anet-analysis/
BibTeX
@misc{bio-epitranscriptomics-m6anet-analysis--skills-m6anet-analysis-2026,
author = {bg-szy},
title = {bio-epitranscriptomics-m6anet-analysis [Claude Code skill]},
year = {2026},
publisher = {ClaudSkills},
url = {https://claudskills.com/skills/bio-epitranscriptomics-m6anet-analysis--skills-m6anet-analysis/}
}
Embed this skill
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Badge
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Security scan
Grade A · scanned 2026-08-07 — free static scan against the OWASP Agentic Skills Top 10.
No risk patterns were found in any of the ten OWASP-aligned categories. How grading works ›
- ✓ Prompt injection
- ✓ Data exfiltration
- ✓ Supply chain
- ✓ Reverse shell
- ✓ Credentials
- ✓ Execution
- ✓ Filesystem
- ✓ Persistence
- ✓ Obfuscation
- ✓ Network
Show this grade on your repo (click to copy):
[](https://claudskills.com/skills/bio-epitranscriptomics-m6anet-analysis--skills-m6anet-analysis/#security)
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