Claude Code Skills·Claude Skills·The open SKILL.md registry for Claude
ClaudSkills / Science & Research / biology-medicine

Hi C Coverage Track Computation

Category: Science & Research  ·  Sub-category: biology-medicine  ·  Last updated:
Use when you have a cooler file (.cool or .mcool) from a Hi-C experiment and need to generate a genome-wide track of per-bin sequencing depth to assess coverage uniformity, identify poorly sequenced regions, or normalize downstream analyses by local sequencing intensity.
Security AStatic scan found no risk patternsHow grading works ›

About this skill (catalog notes)

Hi C Coverage Track Computation includes explicit scope boundaries (an explicit 'when not to use' or 'out of scope' section); worked examples; at least one code block. The SKILL.md runs to about 756 words, in the catalog's typical mid-range.

Source
holobiomicslab.cnrs.fr
License
Apache-2.0
Original author
HolobiomicsLab
Indexed lastmod
Catalog position
Science & Research · biology-medicine
Indexed related skills
10

How Hi C Coverage Track Computation fits the catalog

Hi C Coverage Track Computation sits in the Science & Research category under the biology-medicine sub-topic in the ClaudSkills catalog. There are 10 related skills indexed alongside it; comparing a few before installing usually reveals which fits your workflow best.

These notes are auto-generated from features detected in the SKILL.md file and from this catalog's structure — they aren't part of the source repository.

What this skill does

Hi C Coverage Track Computation is a community-contributed Claude Code skill in the biology-medicine sub-category. It ships as a SKILL.md file that Claude Code auto-discovers under ~/.claude/skills/hi-c-coverage-track-computation/ and loads when your prompt matches the skill's trigger.

When to invoke it: Use when you have a cooler file (.cool or .

Who uses this skill

The Hi C Coverage Track Computation Claude Code skill is built for researchers, data scientists, academics, and analysts working with complex data and scientific literature. It's part of ClaudSkills (also referred to as Claude Skills or Claude Code Skills) — the open community-curated registry of 146,000+ SKILL.md files for Anthropic's Claude Code agent and the wider Claude ecosystem (Claude API, Claude Agent SDK).

How to install

Free

Manual install (2 steps)

mkdir -p ~/.claude/skills/hi-c-coverage-track-computation
curl -L https://claudskills.com/skills/hi-c-coverage-track-computation/SKILL.md \
  -o ~/.claude/skills/hi-c-coverage-track-computation/SKILL.md

Or just download SKILL.md directly and drop it into ~/.claude/skills/hi-c-coverage-track-computation/. Claude Code auto-discovers it on next session.

Skills live at ~/.claude/skills/hi-c-coverage-track-computation/SKILL.md on macOS/Linux, or %USERPROFILE%\.claude\skills\hi-c-coverage-track-computation\SKILL.md on Windows. See the full install guide for step-by-step instructions.

Telegram

📱 Install from your phone or desktop Telegram

Open @claudskills_bot on Telegram, tap Open Desktop App, and the desktop app installs this skill for you. Or share the bot link with a colleague — they get the same one-tap install. Learn more →

Pro

One-click install via the desktop app

The ClaudSkills desktop app installs any skill directly into ~/.claude/skills/ with one click — no terminal required. Pro starts at $9/mo or $149 lifetime.

Pro

For the full experience including quality scoring and one-click install features for each skill — upgrade to Pro.

Frequently asked questions

How do I install the Hi C Coverage Track Computation Claude Code skill?
Install via the ClaudSkills desktop app (one click) or copy SKILL.md from the source repository to ~/.claude/skills/hi-c-coverage-track-computation/SKILL.md and restart Claude Code. Both flows are detailed at claudskills.com/install/.
What does the Hi C Coverage Track Computation skill do?
Use when you have a cooler file (.cool or .mcool) from a Hi-C experiment and need to generate a genome-wide track of per-bin sequencing depth to assess coverage uniformity, identify poorly sequenced regions, or normalize downstream analyses by local sequencing intensity.
Is this skill free to install?
Yes. ClaudSkills is an open registry — every skill keeps its source repository's license, and manual install via copy is free. ClaudSkills Pro ($9/mo, $79/yr, or $149 one-time) adds one-click install via the desktop app and a multi-signal Quality Score.
When should I use the Hi C Coverage Track Computation skill?
Use Hi C Coverage Track Computation when your Claude Code task falls under the Science & Research category — specifically in the biology medicine area. Claude Code auto-discovers installed skills and invokes the right one based on the task description, so you can also ask Claude directly (e.g. "use Hi C Coverage Track Computation" or describe the task and let Claude pick). Browse related skills at /category/science/.
What is a Claude Code skill and how does the Hi C Coverage Track Computation skill fit in?
A Claude Code skill is a SKILL.md file that lives under ~/.claude/skills/<name>/ and tells the Claude Code CLI agent how to perform a specific task (instructions, prompts, allowed tools). Skills are auto-discovered at session start. Hi C Coverage Track Computation is one of 67,000+ skills indexed in the open ClaudSkills catalog, classified under the Science & Research category. Learn more at /learn/what-is-a-claude-skill/.

Attribution & license

Cite this skill

If you reference this skill in a blog post, paper, or documentation, you can cite it as:

APA
HolobiomicsLab. (2026). Hi C Coverage Track Computation [Claude Code skill]. ClaudSkills. https://claudskills.com/skills/hi-c-coverage-track-computation/
BibTeX
@misc{hi-c-coverage-track-computation-2026,
  author    = {HolobiomicsLab},
  title     = {Hi C Coverage Track Computation [Claude Code skill]},
  year      = {2026},
  publisher = {ClaudSkills},
  url       = {https://claudskills.com/skills/hi-c-coverage-track-computation/}
}

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Security scan

Grade A · scanned 2026-07-06 — free static scan against the OWASP Agentic Skills Top 10.

No risk patterns were found in any of the ten OWASP-aligned categories. How grading works ›

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