ClaudSkills / Science & Research / math-stats

Tooluniverse Polygenic Risk Score

Q: What is a Claude Code skill and how does the Tooluniverse Polygenic Risk Score skill fit in?

A Claude Code skill is a SKILL.md file that lives under ~/.claude/skills/<name>/ and tells the Claude Code CLI agent how to perform a specific task (instructions, prompts, allowed tools). Skills are auto-discovered at session start. Tooluniverse Polygenic Risk Score is one of 67,000+ skills indexed in the open ClaudSkills catalog, classified under the Science & Research category. Learn more at https://claudskills.com/learn/what-is-skill-md/.

Category: Science & Research · Sub-category: math-stats · Last updated: 2026-06-02

Build and interpret polygenic risk scores (PRS) for complex diseases using GWAS summary statistics. Calculates genetic risk profiles, interprets PRS percentiles, and assesses disease predisposition across conditions including type 2 diabetes, coronary artery disease, and Alzheimer's disease. Use when asked to calculate polygenic risk scores, interpret genetic risk for complex diseases, build custom PRS from GWAS data, or answer questions like "What is my genetic predisposition to breast cancer?

Security AStatic scan found no risk patternsHow grading works ›

From the source SKILL.md

Build and interpret polygenic risk scores for complex diseases using genome-wide association study (GWAS) data.

What this skill does

Tooluniverse Polygenic Risk Score is a community-contributed Claude Code skill in the math-stats sub-category. It ships as a SKILL.md file that Claude Code auto-discovers under ~/.claude/skills/tooluniverse-polygenic-risk-score/ and loads when your prompt matches the skill's trigger.

Who uses this skill

The Tooluniverse Polygenic Risk Score Claude Code skill is built for researchers, data scientists, academics, and analysts working with complex data and scientific literature. It's part of ClaudSkills (also referred to as Claude Skills or Claude Code Skills) — the open community-curated registry of 161,000+ SKILL.md files for Anthropic's Claude Code agent and the wider Claude ecosystem (Claude API, Claude Agent SDK).

How to install

Free

Manual install (2 steps)

mkdir -p ~/.claude/skills/tooluniverse-polygenic-risk-score
curl -L https://claudskills.com/skills/tooluniverse-polygenic-risk-score/SKILL.md \
  -o ~/.claude/skills/tooluniverse-polygenic-risk-score/SKILL.md

Or just download SKILL.md directly and drop it into ~/.claude/skills/tooluniverse-polygenic-risk-score/. Claude Code auto-discovers it on next session.

Skills live at ~/.claude/skills/tooluniverse-polygenic-risk-score/SKILL.md on macOS/Linux, or %USERPROFILE%\.claude\skills\tooluniverse-polygenic-risk-score\SKILL.md on Windows. See the full install guide for step-by-step instructions.

📱 Install from your phone or desktop Telegram

Open @claudskills_bot on Telegram, tap Open Desktop App, and the desktop app installs this skill for you. Or share the bot link with a colleague — they get the same one-tap install. Learn more →

Pro

One-click install via the desktop app

The ClaudSkills desktop app installs any skill directly into ~/.claude/skills/ with one click — no terminal required. Pro starts at $9/mo or $149 lifetime.

Pro

For the full experience including quality scoring and one-click install features for each skill — upgrade to Pro.

See pricing → Download desktop app

Frequently asked questions

How do I install the Tooluniverse Polygenic Risk Score Claude Code skill?

Install via the ClaudSkills desktop app (one click) or copy SKILL.md from the source repository to ~/.claude/skills/tooluniverse-polygenic-risk-score/SKILL.md and restart Claude Code. Both flows are detailed at claudskills.com/install/.

What does the Tooluniverse Polygenic Risk Score skill do?

Is this skill free to install?

Yes. ClaudSkills is an open registry — every skill keeps its source repository's license, and manual install via copy is free. ClaudSkills Pro ($9/mo, $79/yr, or $149 one-time) adds one-click install via the desktop app and a multi-signal Quality Score.

When should I use the Tooluniverse Polygenic Risk Score skill?

Use Tooluniverse Polygenic Risk Score when your Claude Code task falls under the Science & Research category — specifically in the math stats area. Claude Code auto-discovers installed skills and invokes the right one based on the task description, so you can also ask Claude directly (e.g. "use Tooluniverse Polygenic Risk Score" or describe the task and let Claude pick). Browse related skills at /category/science/.

What is a Claude Code skill and how does the Tooluniverse Polygenic Risk Score skill fit in?

A Claude Code skill is a SKILL.md file that lives under ~/.claude/skills/<name>/ and tells the Claude Code CLI agent how to perform a specific task (instructions, prompts, allowed tools). Skills are auto-discovered at session start. Tooluniverse Polygenic Risk Score is one of 67,000+ skills indexed in the open ClaudSkills catalog, classified under the Science & Research category. Learn more at /learn/what-is-a-claude-skill/.

Attribution & license

Source: https://github.com/bg-szy/TOP-SKILLS/blob/HEAD/skills/awesome-skills/tooluniverse-polygenic-risk-score/SKILL.md
Author: bg-szy
Website: https://bg-szy.github.io/TOP-SKILLS/

Cite this skill

If you reference this skill in a blog post, paper, or documentation, you can cite it as:

APA

bg-szy. (2026). Tooluniverse Polygenic Risk Score [Claude Code skill]. ClaudSkills. https://claudskills.com/skills/tooluniverse-polygenic-risk-score/

BibTeX

@misc{tooluniverse-polygenic-risk-score-2026,
  author    = {bg-szy},
  title     = {Tooluniverse Polygenic Risk Score [Claude Code skill]},
  year      = {2026},
  publisher = {ClaudSkills},
  url       = {https://claudskills.com/skills/tooluniverse-polygenic-risk-score/}
}

Embed this skill

Promote, attribute, or link this skill from your own README, blog post, or documentation. All three snippets are free to use — no sign-up, no API key. More distribution surfaces →

Badge

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Security scan

Grade A · scanned 2026-07-26 — free static scan against the OWASP Agentic Skills Top 10.

No risk patterns were found in any of the ten OWASP-aligned categories. How grading works ›

✓ Prompt injection
✓ Data exfiltration
✓ Supply chain
✓ Reverse shell
✓ Credentials
✓ Execution
✓ Filesystem
✓ Persistence
✓ Obfuscation
✓ Network

Show this grade on your repo (click to copy):

[![Security: A](https://img.shields.io/badge/Security-A-2e7d32)](https://claudskills.com/skills/tooluniverse-polygenic-risk-score/#security)

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Part of ClaudSkills — the open registry for Claude Skills & Claude Code Skills. · What's New · Install guide · About · llms.txt

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