Generates a structured prompt framework for clinical study protocols. Supports Diagnostic, Efficacy, Etiology, and Prognosis studies.
Unified tool for calculating sample sizes for Diagnostic, Efficacy, Etiology, and Prognosis clinical studies.
Computes sample size and power for clinical trials including continuous, binary, and time-to-event endpoints; superiority, non-inferiority, and equivalence designs; FDA 2 — from…
Generate professional clinical decision support (CDS) documents for pharmaceutical and clinical research settings, including patient cohort analyses (biomarker-stratified — from…
Generate professional clinical decision support (CDS) documents for pharmaceutical and clinical research settings, including patient cohort analyses (biomarker-stratified — from…
Guidelines for clinical decision support (CDS) documents: biomarker-stratified cohort analyses and GRADE-graded treatment reports.
Generate professional clinical decision support (CDS) documents for pharmaceutical and clinical research settings, including patient cohort analyses (biomarker-stratified — from…
Foundations of clinical psychology and psychopathology. Covers anxiety disorders (generalized anxiety, panic, phobias, OCD, PTSD), depressive disorders (major depression,…
Clinical variant interpretation using ClinVar, ACMG guidelines, and pathogenicity predictors. Prioritize variants for diagnostic and research applications.
Write comprehensive clinical reports including case reports (CARE guidelines), diagnostic reports (radiology/pathology/lab), clinical trial reports (ICH-E3, SAE, CSR), an — from…
Use when designing a prospective clinical study before submission — selecting and classifying endpoints (primary / key-secondary / exploratory, with surrogate-endpoint flagging),…
Avoid common methodological mistakes in clinical research with MIMIC-IV and eICU databases. Covers immortal time bias, information leakage, selection bias, and other critical…
Verifies clinical claims and citations: PMID/DOI validity, claim accuracy, and evidence-level wording. Use when the user wants existing content fact-checked.
Batch extracts and verifies structured information (PMID, title, abstract, methodology, results, etc.) from clinical research literature using PMIDs.
Drafts U.S. clinical trial agreements governing sponsor–site–investigator relationships under FDA rules (21 CFR Parts 50, 56, 312) and ICH-GCP E6(R2).
Drafts U.S. clinical trial Investigator Agreements between sponsors/CROs and principal investigators or institutions for FDA-regulated drug, biologic, or device studies.
Generate clinical trial protocols for medical devices or drugs through a modular, waypoint-based architecture with research-only and full protocol modes.
Query ClinicalTrials.gov via API v2. Search trials by condition, drug, location, status, or phase. Retrieve trial details by NCT ID, export data, for clinical research an — from…
Query ClinicalTrials.gov via API v2. Search trials by condition, drug, location, status, or phase. Retrieve trial details by NCT ID, export data, for clinical research an — from…
Query ClinicalTrials.gov via API v2. Search trials by condition, drug, location, status, or phase. Retrieve trial details by NCT ID, export data, for clinical research an — from…
Query ClinicalTrials.gov API v2 for trial data. Search by condition, drug/intervention, location, sponsor, or phase; fetch details by NCT ID; filter by status; paginate; export…
Align CLIP-seq reads to the genome with crosslink site awareness. Use when mapping preprocessed CLIP reads for peak calling. — from science/biology-medicine
Count lines of code, analyze codebase size and composition, compare code between versions. Use when the user asks about lines of code, codebase size, language breakdown, or code…
Generate comprehensive clonality statistics and diversity visualizations for TCR/BCR repertoire analysis.
EXPERIMENTAL. After-service retro — review how recent stages and skills executed, identify systemic friction patterns, draft targeted improvement PRs against the plugin.
Analyzes AWS CloudTrail event logs via the Lookup Events API to detect anomalous IAM activity. Uses statistical baselining of API call patterns and flags unusual AssumeRole…
Finds differentially expressed genes (markers) for clusters of T/B cells using Seurat's FindMarkers function.
Detect copy number variations from whole genome sequencing data and generate publication-quality genome-wide CNV plots.
True objective discovery through structured dialogue. 5 Whys analysis, JTBD (Jobs To Be Done), and 6-element structured prompting.
Validates code and provides physics reasoning for the 0-D CO2 lumped-parameter model for geothermal reservoirs.
Constraint-based metabolic modeling (COBRA). FBA, FVA, gene knockouts, flux sampling, SBML models, for systems biology and metabolic engineering analysis.
Constraint-based metabolic modeling (COBRA). FBA, FVA, gene knockouts, flux sampling, SBML models, for systems biology and metabolic engineering analysis. — from bg-szy/TOP-SKILLS
Constraint-based (COBRA) analysis of genome-scale metabolic models: FBA, FVA, knockouts, flux sampling, production envelopes, gapfilling, media optimization.
Constraint-based metabolic modeling (COBRA). FBA, FVA, gene knockouts, flux sampling, SBML models, for systems biology and metabolic engineering analysis.
Provides comprehensive guidance for Cocos2d-x v4 game engine including scene graph, nodes, sprites, actions, animations, physics, rendering, shaders, and platform deployment.
Create well-structured subagents for Claude Code with specialized expertise, proper tool configurations, and effective system prompts.
Codebase investigation methodology and catalog format. Load when surveying the codebase for bug investigation or pre-implementation research.
Use when starting technical work requiring structured approach - writing tests before code (TDD), planning data exploration (EDA), designing statistical analysis, clarifying…
Autonomous multi-agent code evolution system for optimization problems. Use when solving complex optimization problems (packing, geometry, scheduling, search) through evolutionary…
Mentor mode for learning-focused sessions. Guides the user through concepts, architecture, and hands-on experimentation using targeted code snippets — no full code generation.
Research open-source repositories to understand how something is built or works.
Search GitHub for existing implementations of a topic. Use when the user wants to find code examples, libraries, or implementation patterns.
Deep codebase analysis to discover actual coding standards through statistical evidence. Use when analyzing naming conventions, import patterns, or detecting anti-patterns in…
Analyze codebase with tokei (fast line counts by language) and difft (semantic AST-aware diffs). Get quick project overview without manual counting.
Systematic codebase exploration following the Iron Law - understand the problem before exploring code. Four phases with file-finder and web-researcher agents.
Runs CodeClimate analysis on pull request diffs using the CLI engine and reports new issues inline. Calculates maintainability impact scores per changed file.
Tracks Code Climate maintainability scores over time using the Code Climate v1 API. Identifies technical debt hotspots, monitors churn-complexity coupling, and generates weekly…
Adversarial brainstorming. Claude and Codex independently research then debate until Nash equilibrium. For solution exploration, feasibility analysis, exhaustive enumeration.
Delegiert Code-Review, Research-Synthesis, Adversarial-Cross-Check an Codex CLI (`codex exec`, `codex review`).
コードベースを分析し、詳細な実装計画を plan.md に作成する。新機能実装前、改修前、codex-research 後、"codex-plan", "codexで計画作成", "plan.mdを作って", "実装計画を作って" で使う。
Use Codex CLI sandbox mode to try risky changes safely. Isolated experimentation with network disabled and directory restrictions.
Investigate the @openai/codex-sdk API by first inspecting installed .d.ts typings in node_modules, then cloning and searching the github.com/openai/codex repo for source/docs.
Search the web using OpenAI Codex CLI to find current documentation, best practices, solutions, and technical information.
Python research assistant with Context7 MCP. Use for Python library research, evaluating packages, enforcing strict Python coding standards, or fetching up-to-date library docs…
Stay current with how OpenCode, OpenAI Codex, and Claude Code implement extensibility features (skills, slash commands, subagents, custom prompts).
Diagnose and fix broken LLM model configurations in CogniForge microservices. Use when: AI responses are empty, garbage, or missing LaTeX; reasoning-agent returns empty answers or…
Diagnose, build, and repair the CogniForge Math Pipeline — the LangGraph 3-node StateGraph that handles BAC math questions.
Apply cognitive science and HCI research to design decisions. Use when you need the scientific 'why' behind usability, explaining user behavior, understanding…
Drafts cognovit promissory notes with confession of judgment provisions, gated by mandatory jurisdictional enforceability research, usury compliance, and statutory disclosure…
Secure API access to search pathology cases, build research cohorts, and export WSI data with clinical and technical filters