Adaptive Trial Simulator

Q: What is a Claude Code skill and how does the Adaptive Trial Simulator skill fit in?

A Claude Code skill is a SKILL.md file that lives under ~/.claude/skills/<name>/ and tells the Claude Code CLI agent how to perform a specific task (instructions, prompts, allowed tools). Skills are auto-discovered at session start. Adaptive Trial Simulator is one of 67,000+ skills indexed in the open ClaudSkills catalog, classified under the General category. Learn more at https://claudskills.com/learn/what-is-skill-md/.

Category: General · Sub-category: general-misc · Last updated: 2026-06-26

Design and simulate adaptive clinical trials with interim analyses, decision rules, and operating-characteristic summaries; use when planning adaptive designs or comparing stopping, enrichment, or sample-size re-estimation strategies.

Security AStatic scan found no risk patternsHow grading works ›

From the source SKILL.md

Statistical simulation platform for designing and validating adaptive clinical trial designs in silico. Enables optimization of interim analysis strategies, sample size adaptation, and early stopping rules while maintaining Type I error control.

What this skill does

Adaptive Trial Simulator is a community-contributed Claude Code skill in the general-misc sub-category. It ships as a SKILL.md file that Claude Code auto-discovers under ~/.claude/skills/adaptive-trial-simulator/ and loads when your prompt matches the skill's trigger.

When to invoke it: use when planning adaptive designs or comparing stopping, enrichment, or sample-size re-estimation strategies.

Who uses this skill

The Adaptive Trial Simulator Claude Code skill is built for Claude Code users and developers across all disciplines looking for general-purpose AI assistance. It's part of ClaudSkills (also referred to as Claude Skills or Claude Code Skills) — the open community-curated registry of 146,000+ SKILL.md files for Anthropic's Claude Code agent and the wider Claude ecosystem (Claude API, Claude Agent SDK).

How to install

Free

Manual install (2 steps)

mkdir -p ~/.claude/skills/adaptive-trial-simulator
curl -L https://claudskills.com/skills/adaptive-trial-simulator/SKILL.md \
  -o ~/.claude/skills/adaptive-trial-simulator/SKILL.md

Or just download SKILL.md directly and drop it into ~/.claude/skills/adaptive-trial-simulator/. Claude Code auto-discovers it on next session.

Skills live at ~/.claude/skills/adaptive-trial-simulator/SKILL.md on macOS/Linux, or %USERPROFILE%\.claude\skills\adaptive-trial-simulator\SKILL.md on Windows. See the full install guide for step-by-step instructions.

📱 Install from your phone or desktop Telegram

Open @claudskills_bot on Telegram, tap Open Desktop App, and the desktop app installs this skill for you. Or share the bot link with a colleague — they get the same one-tap install. Learn more →

Pro

One-click install via the desktop app

The ClaudSkills desktop app installs any skill directly into ~/.claude/skills/ with one click — no terminal required. Pro starts at $9/mo or $149 lifetime.

Pro

For the full experience including quality scoring and one-click install features for each skill — upgrade to Pro.

See pricing → Download desktop app

Frequently asked questions

How do I install the Adaptive Trial Simulator Claude Code skill?

Install via the ClaudSkills desktop app (one click) or copy SKILL.md from the source repository to ~/.claude/skills/adaptive-trial-simulator/SKILL.md and restart Claude Code. Both flows are detailed at claudskills.com/install/.

What does the Adaptive Trial Simulator skill do?

Is this skill free to install?

Yes. ClaudSkills is an open registry — every skill keeps its source repository's license, and manual install via copy is free. ClaudSkills Pro ($9/mo, $79/yr, or $149 one-time) adds one-click install via the desktop app and a multi-signal Quality Score.

When should I use the Adaptive Trial Simulator skill?

Use Adaptive Trial Simulator when your Claude Code task falls under the General category — specifically in the general misc area. Claude Code auto-discovers installed skills and invokes the right one based on the task description, so you can also ask Claude directly (e.g. "use Adaptive Trial Simulator" or describe the task and let Claude pick). Browse related skills at /category/general/.

What is a Claude Code skill and how does the Adaptive Trial Simulator skill fit in?

A Claude Code skill is a SKILL.md file that lives under ~/.claude/skills/<name>/ and tells the Claude Code CLI agent how to perform a specific task (instructions, prompts, allowed tools). Skills are auto-discovered at session start. Adaptive Trial Simulator is one of 67,000+ skills indexed in the open ClaudSkills catalog, classified under the General category. Learn more at /learn/what-is-a-claude-skill/.

Attribution & license

Source: https://github.com/aipoch/medical-research-skills/blob/HEAD/scientific-skills/Protocol Design/adaptive-trial-simulator/SKILL.md
License: MIT
Author: AIPOCH
Website: https://aipoch.com/agent-skills

Cite this skill

If you reference this skill in a blog post, paper, or documentation, you can cite it as:

APA

AIPOCH. (2026). Adaptive Trial Simulator [Claude Code skill]. ClaudSkills. https://claudskills.com/skills/adaptive-trial-simulator/

BibTeX

@misc{adaptive-trial-simulator-2026,
  author    = {AIPOCH},
  title     = {Adaptive Trial Simulator [Claude Code skill]},
  year      = {2026},
  publisher = {ClaudSkills},
  url       = {https://claudskills.com/skills/adaptive-trial-simulator/}
}

Embed this skill

Promote, attribute, or link this skill from your own README, blog post, or documentation. All three snippets are free to use — no sign-up, no API key. More distribution surfaces →

Badge

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Security scan

Grade A · scanned 2026-07-06 — free static scan against the OWASP Agentic Skills Top 10.

No risk patterns were found in any of the ten OWASP-aligned categories. How grading works ›

✓ Prompt injection
✓ Data exfiltration
✓ Supply chain
✓ Reverse shell
✓ Credentials
✓ Execution
✓ Filesystem
✓ Persistence
✓ Obfuscation
✓ Network

Show this grade on your repo (click to copy):

[![Security: A](https://img.shields.io/badge/Security-A-2e7d32)](https://claudskills.com/skills/adaptive-trial-simulator/#security)

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Part of ClaudSkills — the open registry for Claude Skills & Claude Code Skills. · What's New · Install guide · About · llms.txt

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