ClaudSkills / General / orchestration-frameworks

bio-clinical-databases-gnomad-frequencies

Q: What is a Claude Code skill and how does the bio-clinical-databases-gnomad-frequencies skill fit in?

A Claude Code skill is a SKILL.md file that lives under ~/.claude/skills/<name>/ and tells the Claude Code CLI agent how to perform a specific task (instructions, prompts, allowed tools). Skills are auto-discovered at session start. bio-clinical-databases-gnomad-frequencies is one of 67,000+ skills indexed in the open ClaudSkills catalog, classified under the General category. Learn more at https://claudskills.com/learn/what-is-skill-md/.

Category: General · Sub-category: orchestration-frameworks · Last updated: 2026-06-02

Queries gnomAD v4 (807k samples), v3, v2.1.1, and constraint metrics with grpmax FAF95, bottleneck-group exclusion, LOEUF interpretation, SV/CNV/mtDNA catalogs, and Whiffin max-credible-AF framework. Use when filtering rare variants, applying ACMG BS1/BA1, ranking genes by LoF intolerance, or selecting between v2 (GRCh37 + chrX/Y constraint) and v4 (GRCh38 + 807k samples).

About this skill (catalog notes)

bio-clinical-databases-gnomad-frequencies includes pricing or quota commentary; at least one code block. At roughly 3,328 words the SKILL.md is on the longer end of the catalog distribution.

Source: bg-szy.github.io/TOP-SKILLS
Original author: bg-szy
Indexed lastmod: 2026-06-02
Catalog position: General · orchestration-frameworks
Indexed related skills: 10

How bio-clinical-databases-gnomad-frequencies fits the catalog

bio-clinical-databases-gnomad-frequencies sits in the General category under the orchestration-frameworks sub-topic in the ClaudSkills catalog. There are 10 related skills indexed alongside it; comparing a few before installing usually reveals which fits your workflow best.

These notes are auto-generated from features detected in the SKILL.md file and from this catalog's structure — they aren't part of the source repository.

What this skill does

bio-clinical-databases-gnomad-frequencies is a community-contributed Claude Code skill in the orchestration-frameworks sub-category. It ships as a SKILL.md file that Claude Code auto-discovers under ~/.claude/skills/bio-clinical-databases-gnomad-frequencies--skills-gnomad-frequen/ and loads when your prompt matches the skill's trigger.

When to invoke it: Use when filtering rare variants, applying ACMG BS1/BA1, ranking genes by LoF intolerance, or selecting between v2 (GRCh37 + chrX/Y constraint) and v4 (GRCh38 + 807k samples).

Who uses this skill

The bio-clinical-databases-gnomad-frequencies Claude Code skill is built for Claude Code users and developers across all disciplines looking for general-purpose AI assistance. It's part of ClaudSkills (also referred to as Claude Skills or Claude Code Skills) — the open community-curated registry of 85,000+ SKILL.md files for Anthropic's Claude Code agent and the wider Claude ecosystem (Claude API, Claude Agent SDK).

How to install

Free

Manual install (2 steps)

mkdir -p ~/.claude/skills/bio-clinical-databases-gnomad-frequencies--skills-gnomad-frequen
curl -L https://claudskills.com/skills/bio-clinical-databases-gnomad-frequencies--skills-gnomad-frequen/SKILL.md \
  -o ~/.claude/skills/bio-clinical-databases-gnomad-frequencies--skills-gnomad-frequen/SKILL.md

Or just download SKILL.md directly and drop it into ~/.claude/skills/bio-clinical-databases-gnomad-frequencies--skills-gnomad-frequen/. Claude Code auto-discovers it on next session.

Skills live at ~/.claude/skills/bio-clinical-databases-gnomad-frequencies--skills-gnomad-frequen/SKILL.md on macOS/Linux, or %USERPROFILE%\.claude\skills\bio-clinical-databases-gnomad-frequencies--skills-gnomad-frequen\SKILL.md on Windows. See the full install guide for step-by-step instructions.

Pro

One-click install via the desktop app

The ClaudSkills desktop app installs any skill directly into ~/.claude/skills/ with one click — no terminal required. Pro starts at $9/mo or $149 lifetime.

Pro

For the full experience including quality scoring and one-click install features for each skill — upgrade to Pro.

See pricing → Download desktop app

Frequently asked questions

How do I install the bio-clinical-databases-gnomad-frequencies Claude Code skill?

Install via the ClaudSkills desktop app (one click) or copy SKILL.md from the source repository to ~/.claude/skills/bio-clinical-databases-gnomad-frequencies--skills-gnomad-frequen/SKILL.md and restart Claude Code. Both flows are detailed at claudskills.com/install/.

What does the bio-clinical-databases-gnomad-frequencies skill do?

Is this skill free to install?

Yes. ClaudSkills is an open registry — every skill keeps its source repository's license, and manual install via copy is free. ClaudSkills Pro ($9/mo, $79/yr, or $149 one-time) adds one-click install via the desktop app and a multi-signal Quality Score.

When should I use the bio-clinical-databases-gnomad-frequencies skill?

Use bio-clinical-databases-gnomad-frequencies when your Claude Code task falls under the General category — specifically in the orchestration frameworks area. Claude Code auto-discovers installed skills and invokes the right one based on the task description, so you can also ask Claude directly (e.g. "use bio-clinical-databases-gnomad-frequencies" or describe the task and let Claude pick). Browse related skills at /category/general/.

What is a Claude Code skill and how does the bio-clinical-databases-gnomad-frequencies skill fit in?

A Claude Code skill is a SKILL.md file that lives under ~/.claude/skills/<name>/ and tells the Claude Code CLI agent how to perform a specific task (instructions, prompts, allowed tools). Skills are auto-discovered at session start. bio-clinical-databases-gnomad-frequencies is one of 67,000+ skills indexed in the open ClaudSkills catalog, classified under the General category. Learn more at /learn/what-is-a-claude-skill/.

Attribution & license

Source: https://github.com/bg-szy/TOP-SKILLS/blob/HEAD/skills/awesome-skills/bio-clinical-databases-gnomad-frequencies__skills-gnomad-frequencies/SKILL.md
Author: bg-szy
Website: https://bg-szy.github.io/TOP-SKILLS/

Cite this skill

If you reference this skill in a blog post, paper, or documentation, you can cite it as:

APA

bg-szy. (2026). bio-clinical-databases-gnomad-frequencies [Claude Code skill]. ClaudSkills. https://claudskills.com/skills/bio-clinical-databases-gnomad-frequencies--skills-gnomad-frequen/

BibTeX

@misc{bio-clinical-databases-gnomad-frequencies--skills-gnomad-frequen-2026,
  author    = {bg-szy},
  title     = {bio-clinical-databases-gnomad-frequencies [Claude Code skill]},
  year      = {2026},
  publisher = {ClaudSkills},
  url       = {https://claudskills.com/skills/bio-clinical-databases-gnomad-frequencies--skills-gnomad-frequen/}
}

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