Bio Methylation Array Qc Filtering

Q: What is a Claude Code skill and how does the Bio Methylation Array Qc Filtering skill fit in?

A Claude Code skill is a SKILL.md file that lives under ~/.claude/skills/<name>/ and tells the Claude Code CLI agent how to perform a specific task (instructions, prompts, allowed tools). Skills are auto-discovered at session start. Bio Methylation Array Qc Filtering is one of 67,000+ skills indexed in the open ClaudSkills catalog, classified under the General category. Learn more at https://claudskills.com/learn/what-is-skill-md/.

Category: General · Sub-category: general-misc · Last updated: 2026-07-11

Performs probe filtering and sample-level QC on Illumina Infinium methylation arrays (450K / EPIC / EPICv2) to decide which probes and samples to trust. Drops detection-p-failed and low-bead-count probes, removes cross-reactive/non-specific probes (Chen 2013 / Pidsley 2016 lists via maxprobes), excludes SNP-overlapping probes with dropLociWithSnps, and handles sex-chromosome probes. Collapses EPICv2 replicate probes with betasCollapseToPfx and harmonizes across array versions (EPICv2 hg38 vs 450K/EPIC hg19, intersect plus mLiftOver). Runs sample-identity QC: getSex sex prediction vs sample sheet for swap detection, rs-SNP fingerprint clustering for duplicates/swaps, and Sentrix chip/array-position batch diagnosis. Use when filtering methylation array probes, detecting sample swaps or mislabels, collapsing EPICv2 replicates, or merging 450K/EPIC/EPICv2 cohorts. For IDAT-to-corrected-beta normalization see array-preprocessing; for batch correction and study design see ewas-design.

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What this skill does

Bio Methylation Array Qc Filtering is a community-contributed Claude Code skill in the general-misc sub-category. It ships as a SKILL.md file that Claude Code auto-discovers under ~/.claude/skills/bio-methylation-array-qc-filtering/ and loads when your prompt matches the skill's trigger.

When to invoke it: Use when filtering methylation array probes, detecting sample swaps or mislabels, collapsing EPICv2 replicates, or merging 450K/EPIC/EPICv2 cohorts. For IDAT-to-corrected-beta normalization see array-preprocessing; for batch correction and study design see ewas-design.

Who uses this skill

The Bio Methylation Array Qc Filtering Claude Code skill is built for Claude Code users and developers across all disciplines looking for general-purpose AI assistance. It's part of ClaudSkills (also referred to as Claude Skills or Claude Code Skills) — the open community-curated registry of 196,000+ SKILL.md files for Anthropic's Claude Code agent and the wider Claude ecosystem (Claude API, Claude Agent SDK).

How to install

Free

Manual install (2 steps)

mkdir -p ~/.claude/skills/bio-methylation-array-qc-filtering
curl -L https://claudskills.com/skills/bio-methylation-array-qc-filtering/SKILL.md \
  -o ~/.claude/skills/bio-methylation-array-qc-filtering/SKILL.md

Or just download SKILL.md directly and drop it into ~/.claude/skills/bio-methylation-array-qc-filtering/. Claude Code auto-discovers it on next session.

Skills live at ~/.claude/skills/bio-methylation-array-qc-filtering/SKILL.md on macOS/Linux, or %USERPROFILE%\.claude\skills\bio-methylation-array-qc-filtering\SKILL.md on Windows. See the full install guide for step-by-step instructions.

📱 Install from your phone or desktop Telegram

Open @claudskills_bot on Telegram, tap Open Desktop App, and the desktop app installs this skill for you. Or share the bot link with a colleague — they get the same one-tap install. Learn more →

Pro

One-click install via the desktop app

The ClaudSkills desktop app installs any skill directly into ~/.claude/skills/ with one click — no terminal required. Pro starts at $9/mo or $149 lifetime.

Pro

For the full experience including quality scoring and one-click install features for each skill — upgrade to Pro.

See pricing → Download desktop app

Frequently asked questions

How do I install the Bio Methylation Array Qc Filtering Claude Code skill?

Install via the ClaudSkills desktop app (one click) or copy SKILL.md from the source repository to ~/.claude/skills/bio-methylation-array-qc-filtering/SKILL.md and restart Claude Code. Both flows are detailed at claudskills.com/install/.

What does the Bio Methylation Array Qc Filtering skill do?

Is this skill free to install?

Yes. ClaudSkills is an open registry — every skill keeps its source repository's license, and manual install via copy is free. ClaudSkills Pro ($9/mo, $79/yr, or $149 one-time) adds one-click install via the desktop app and a multi-signal Quality Score.

When should I use the Bio Methylation Array Qc Filtering skill?

Use Bio Methylation Array Qc Filtering when your Claude Code task falls under the General category — specifically in the general misc area. Claude Code auto-discovers installed skills and invokes the right one based on the task description, so you can also ask Claude directly (e.g. "use Bio Methylation Array Qc Filtering" or describe the task and let Claude pick). Browse related skills at /category/general/.

What is a Claude Code skill and how does the Bio Methylation Array Qc Filtering skill fit in?

A Claude Code skill is a SKILL.md file that lives under ~/.claude/skills/<name>/ and tells the Claude Code CLI agent how to perform a specific task (instructions, prompts, allowed tools). Skills are auto-discovered at session start. Bio Methylation Array Qc Filtering is one of 67,000+ skills indexed in the open ClaudSkills catalog, classified under the General category. Learn more at /learn/what-is-a-claude-skill/.

Attribution & license

Source: https://github.com/bg-szy/TOP-SKILLS/blob/HEAD/skills/awesome-skills/bio-methylation-array-qc-filtering/SKILL.md
Author: bg-szy
Website: https://bg-szy.github.io/TOP-SKILLS/

Cite this skill

If you reference this skill in a blog post, paper, or documentation, you can cite it as:

APA

bg-szy. (2026). Bio Methylation Array Qc Filtering [Claude Code skill]. ClaudSkills. https://claudskills.com/skills/bio-methylation-array-qc-filtering/

BibTeX

@misc{bio-methylation-array-qc-filtering-2026,
  author    = {bg-szy},
  title     = {Bio Methylation Array Qc Filtering [Claude Code skill]},
  year      = {2026},
  publisher = {ClaudSkills},
  url       = {https://claudskills.com/skills/bio-methylation-array-qc-filtering/}
}

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Security scan

Grade A · scanned 2026-09-28 — free static scan against the OWASP Agentic Skills Top 10.

No risk patterns were found in any of the ten OWASP-aligned categories. How grading works ›

✓ Prompt injection
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✓ Filesystem
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✓ Network

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