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Esm2 Sequence Scoring

Category: General  ·  Sub-category: general-misc  ·  Last updated:
ESM2 protein language model for sequence scoring, embeddings, and plausibility checks. Use this skill when: (1) Computing pseudo-log-likelihood (PLL) scores, (2) Getting protein embeddings for clustering, (3) Filtering designs by sequence plausibility, (4) Zero-shot variant effect prediction, (5) Analyzing sequence-function relationships.
Security AStatic scan found no risk patternsHow grading works ›

From the source SKILL.md

Plain-language role: Use ESM when you want sequence-level scoring or embeddings rather than 3D structure prediction.

What this skill does

Esm2 Sequence Scoring is a community-contributed Claude Code skill in the general-misc sub-category. It ships as a SKILL.md file that Claude Code auto-discovers under ~/.claude/skills/esm2-sequence-scoring/ and loads when your prompt matches the skill's trigger.

Who uses this skill

The Esm2 Sequence Scoring Claude Code skill is built for Claude Code users and developers across all disciplines looking for general-purpose AI assistance. It's part of ClaudSkills (also referred to as Claude Skills or Claude Code Skills) — the open community-curated registry of 196,000+ SKILL.md files for Anthropic's Claude Code agent and the wider Claude ecosystem (Claude API, Claude Agent SDK).

How to install

Free

Manual install (2 steps)

mkdir -p ~/.claude/skills/esm2-sequence-scoring
curl -L https://claudskills.com/skills/esm2-sequence-scoring/SKILL.md \
  -o ~/.claude/skills/esm2-sequence-scoring/SKILL.md

Or just download SKILL.md directly and drop it into ~/.claude/skills/esm2-sequence-scoring/. Claude Code auto-discovers it on next session.

Skills live at ~/.claude/skills/esm2-sequence-scoring/SKILL.md on macOS/Linux, or %USERPROFILE%\.claude\skills\esm2-sequence-scoring\SKILL.md on Windows. See the full install guide for step-by-step instructions.

Telegram

📱 Install from your phone or desktop Telegram

Open @claudskills_bot on Telegram, tap Open Desktop App, and the desktop app installs this skill for you. Or share the bot link with a colleague — they get the same one-tap install. Learn more →

Pro

One-click install via the desktop app

The ClaudSkills desktop app installs any skill directly into ~/.claude/skills/ with one click — no terminal required. Pro starts at $9/mo or $149 lifetime.

Pro

For the full experience including quality scoring and one-click install features for each skill — upgrade to Pro.

Frequently asked questions

How do I install the Esm2 Sequence Scoring Claude Code skill?
Install via the ClaudSkills desktop app (one click) or copy SKILL.md from the source repository to ~/.claude/skills/esm2-sequence-scoring/SKILL.md and restart Claude Code. Both flows are detailed at claudskills.com/install/.
What does the Esm2 Sequence Scoring skill do?
ESM2 protein language model for sequence scoring, embeddings, and plausibility checks. Use this skill when: (1) Computing pseudo-log-likelihood (PLL) scores, (2) Getting protein embeddings for clustering, (3) Filtering designs by sequence plausibility, (4) Zero-shot variant effect prediction, (5) Analyzing sequence-function relationships.
Is this skill free to install?
Yes. ClaudSkills is an open registry — every skill keeps its source repository's license, and manual install via copy is free. ClaudSkills Pro ($9/mo, $79/yr, or $149 one-time) adds one-click install via the desktop app and a multi-signal Quality Score.
When should I use the Esm2 Sequence Scoring skill?
Use Esm2 Sequence Scoring when your Claude Code task falls under the General category — specifically in the general misc area. Claude Code auto-discovers installed skills and invokes the right one based on the task description, so you can also ask Claude directly (e.g. "use Esm2 Sequence Scoring" or describe the task and let Claude pick). Browse related skills at /category/general/.
What is a Claude Code skill and how does the Esm2 Sequence Scoring skill fit in?
A Claude Code skill is a SKILL.md file that lives under ~/.claude/skills/<name>/ and tells the Claude Code CLI agent how to perform a specific task (instructions, prompts, allowed tools). Skills are auto-discovered at session start. Esm2 Sequence Scoring is one of 67,000+ skills indexed in the open ClaudSkills catalog, classified under the General category. Learn more at /learn/what-is-a-claude-skill/.

Attribution & license

Cite this skill

If you reference this skill in a blog post, paper, or documentation, you can cite it as:

APA
BioTender-max. (2026). Esm2 Sequence Scoring [Claude Code skill]. ClaudSkills. https://claudskills.com/skills/esm2-sequence-scoring/
BibTeX
@misc{esm2-sequence-scoring-2026,
  author    = {BioTender-max},
  title     = {Esm2 Sequence Scoring [Claude Code skill]},
  year      = {2026},
  publisher = {ClaudSkills},
  url       = {https://claudskills.com/skills/esm2-sequence-scoring/}
}

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Security scan

Grade A · scanned 2026-09-28 — free static scan against the OWASP Agentic Skills Top 10.

The scan flagged 2 of 10 categories (execution, filesystem), including lower-severity patterns. Patterns shown inside code fences are weighted as examples rather than instructions — read the grading methodology for what this does and does not guarantee.

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Part of ClaudSkills — the open registry for Claude Skills & Claude Code Skills.  ·  What's New  ·  Install guide  ·  About  ·  llms.txt

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