Hi C Matrix Normalization Pipeline Setup includes explicit scope boundaries (an explicit 'when not to use' or 'out of scope' section); worked examples; at least one code block. The SKILL.md runs to about 855 words, in the catalog's typical mid-range.
Hi C Matrix Normalization Pipeline Setup sits in the General category under the workflow-pipelines sub-topic in the ClaudSkills catalog. There are 10 related skills indexed alongside it; comparing a few before installing usually reveals which fits your workflow best.
These notes are auto-generated from features detected in the SKILL.md file and from this catalog's structure — they aren't part of the source repository.
Hi C Matrix Normalization Pipeline Setup is a community-contributed Claude Code skill in the workflow-pipelines sub-category. It ships as a SKILL.md file that Claude Code auto-discovers under ~/.claude/skills/hi-c-matrix-normalization-pipeline-setup/ and loads when your prompt matches the skill's trigger.
When to invoke it: Use when before running HiC-Pro's normalization stage on aligned Hi-C BAM files. Specifically, when you have SAM/BAM-formatted aligned Hi-C reads that need bias correction and matrix balancing to produce normalized contact maps suitable for downstream chromatin structure analysis.
The Hi C Matrix Normalization Pipeline Setup Claude Code skill is built for Claude Code users and developers across all disciplines looking for general-purpose AI assistance. It's part of ClaudSkills (also referred to as Claude Skills or Claude Code Skills) — the open community-curated registry of 146,000+ SKILL.md files for Anthropic's Claude Code agent and the wider Claude ecosystem (Claude API, Claude Agent SDK).
mkdir -p ~/.claude/skills/hi-c-matrix-normalization-pipeline-setup curl -L https://claudskills.com/skills/hi-c-matrix-normalization-pipeline-setup/SKILL.md \ -o ~/.claude/skills/hi-c-matrix-normalization-pipeline-setup/SKILL.md
Or just download SKILL.md directly and drop it into ~/.claude/skills/hi-c-matrix-normalization-pipeline-setup/. Claude Code auto-discovers it on next session.
Skills live at ~/.claude/skills/hi-c-matrix-normalization-pipeline-setup/SKILL.md on macOS/Linux, or %USERPROFILE%\.claude\skills\hi-c-matrix-normalization-pipeline-setup\SKILL.md on Windows. See the full install guide for step-by-step instructions.
Open @claudskills_bot on Telegram, tap Open Desktop App, and the desktop app installs this skill for you. Or share the bot link with a colleague — they get the same one-tap install. Learn more →
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SKILL.md from the source repository to ~/.claude/skills/hi-c-matrix-normalization-pipeline-setup/SKILL.md and restart Claude Code. Both flows are detailed at claudskills.com/install/.SKILL.md file that lives under ~/.claude/skills/<name>/ and tells the Claude Code CLI agent how to perform a specific task (instructions, prompts, allowed tools). Skills are auto-discovered at session start. Hi C Matrix Normalization Pipeline Setup is one of 67,000+ skills indexed in the open ClaudSkills catalog, classified under the General category. Learn more at /learn/what-is-a-claude-skill/.If you reference this skill in a blog post, paper, or documentation, you can cite it as:
@misc{hi-c-matrix-normalization-pipeline-setup-2026,
author = {HolobiomicsLab},
title = {Hi C Matrix Normalization Pipeline Setup [Claude Code skill]},
year = {2026},
publisher = {ClaudSkills},
url = {https://claudskills.com/skills/hi-c-matrix-normalization-pipeline-setup/}
}Grade A · scanned 2026-07-06 — free static scan against the OWASP Agentic Skills Top 10.
The scan flagged 1 of 10 categories (supply-chain), including lower-severity patterns. Patterns shown inside code fences are weighted as examples rather than instructions — read the grading methodology for what this does and does not guarantee.
Browse all General skills in the ClaudSkills registry, or explore these other picks from the same category:
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SKILL.md files, not affiliated with, endorsed by, or sponsored by Anthropic.