Mendelian Randomization Protocol Designer
Generates complete Mendelian randomization study designs from a user-provided exposure and outcome direction. Always use this skill whenever a user wants to design, plan, or build a Mendelian randomization study — even if phrased as "help me write a paper on X", "design an MR study for Y", or "I want to test whether A causally affects B using GWAS". Covers core two-sample MR design, optional bidirectional follow-up, optional multivariable MR, IV selection logic, ancestry alignment, harmonization, IVW as the default primary estimator, weighted median / MR-Egger / MR-PRESSO / leave-one-out sensitivity analyses, Steiger directionality, heterogeneity / pleiotropy checks, and explicit claim-boundary control. Always outputs four workload configs (Lite / Standard / Advanced / Publication+) with a recommended primary plan, stepwise workflow, method rationale, validation ladder, figure plan, minimal executable version, and strictly verified literature guidance with no fabricated references.
Security AStatic scan found no risk patternsHow grading works ›
From the source SKILL.md
You are an expert Mendelian randomization study-design planner.
What this skill does
Mendelian Randomization Protocol Designer is a community-contributed Claude Code skill in the general-misc sub-category. It ships as a SKILL.md file that Claude Code auto-discovers under ~/.claude/skills/mendelian-randomization-protocol-designer/ and loads when your prompt matches the skill's trigger.
Who uses this skill
The Mendelian Randomization Protocol Designer Claude Code skill is built for Claude Code users and developers across all disciplines looking for general-purpose AI assistance. It's part of ClaudSkills (also referred to as Claude Skills or Claude Code Skills) — the open community-curated registry of 146,000+ SKILL.md files for Anthropic's Claude Code agent and the wider Claude ecosystem (Claude API, Claude Agent SDK).
How to install
Free
Manual install (2 steps)
mkdir -p ~/.claude/skills/mendelian-randomization-protocol-designer
curl -L https://claudskills.com/skills/mendelian-randomization-protocol-designer/SKILL.md \
-o ~/.claude/skills/mendelian-randomization-protocol-designer/SKILL.md
Or just download SKILL.md directly and drop it into ~/.claude/skills/mendelian-randomization-protocol-designer/. Claude Code auto-discovers it on next session.
Skills live at ~/.claude/skills/mendelian-randomization-protocol-designer/SKILL.md on macOS/Linux, or %USERPROFILE%\.claude\skills\mendelian-randomization-protocol-designer\SKILL.md on Windows. See the full install guide for step-by-step instructions.
Telegram
📱 Install from your phone or desktop Telegram
Open @claudskills_bot on Telegram, tap Open Desktop App, and the desktop app installs this skill for you. Or share the bot link with a colleague — they get the same one-tap install. Learn more →
Pro
One-click install via the desktop app
The ClaudSkills desktop app installs any skill directly into ~/.claude/skills/ with one click — no terminal required. Pro starts at $9/mo or $149 lifetime.
Pro
For the full experience including quality scoring and one-click install features for each skill — upgrade to Pro.
Frequently asked questions
How do I install the Mendelian Randomization Protocol Designer Claude Code skill?
Install via the ClaudSkills desktop app (one click) or copy
SKILL.md from the source repository to
~/.claude/skills/mendelian-randomization-protocol-designer/SKILL.md and restart Claude Code. Both flows are detailed at
claudskills.com/install/.
What does the Mendelian Randomization Protocol Designer skill do?
Generates complete Mendelian randomization study designs from a user-provided exposure and outcome direction. Always use this skill whenever a user wants to design, plan, or build a Mendelian randomization study — even if phrased as "help me write a paper on X", "design an MR study for Y", or "I want to test whether A causally affects B using GWAS". Covers core two-sample MR design, optional bidirectional follow-up, optional multivariable MR, IV selection logic, ancestry alignment, harmonization, IVW as the default primary estimator, weighted median / MR-Egger / MR-PRESSO / leave-one-out sensitivity analyses, Steiger directionality, heterogeneity / pleiotropy checks, and explicit claim-boundary control. Always outputs four workload configs (Lite / Standard / Advanced / Publication+) with a recommended primary plan, stepwise workflow, method rationale, validation ladder, figure plan, minimal executable version, and strictly verified literature guidance with no fabricated references.
Is this skill free to install?
Yes. ClaudSkills is an open registry — every skill keeps its source repository's license, and manual install via copy is free. ClaudSkills Pro ($9/mo, $79/yr, or $149 one-time) adds one-click install via the desktop app and a multi-signal Quality Score.
When should I use the Mendelian Randomization Protocol Designer skill?
Use Mendelian Randomization Protocol Designer when your Claude Code task falls under the General category — specifically in the general misc area. Claude Code auto-discovers installed skills and invokes the right one based on the task description, so you can also ask Claude directly (e.g. "use Mendelian Randomization Protocol Designer" or describe the task and let Claude pick). Browse related skills at
/category/general/.
What is a Claude Code skill and how does the Mendelian Randomization Protocol Designer skill fit in?
A Claude Code skill is a
SKILL.md file that lives under
~/.claude/skills/<name>/ and tells the Claude Code CLI agent how to perform a specific task (instructions, prompts, allowed tools). Skills are auto-discovered at session start. Mendelian Randomization Protocol Designer is one of 67,000+ skills indexed in the open ClaudSkills catalog, classified under the General category. Learn more at
/learn/what-is-a-claude-skill/.
Attribution & license
- License: MIT
- Author: AIPOCH
Cite this skill
If you reference this skill in a blog post, paper, or documentation, you can cite it as:
APA
AIPOCH. (2026). Mendelian Randomization Protocol Designer [Claude Code skill]. ClaudSkills. https://claudskills.com/skills/mendelian-randomization-protocol-designer/
BibTeX
@misc{mendelian-randomization-protocol-designer-2026,
author = {AIPOCH},
title = {Mendelian Randomization Protocol Designer [Claude Code skill]},
year = {2026},
publisher = {ClaudSkills},
url = {https://claudskills.com/skills/mendelian-randomization-protocol-designer/}
}Embed this skill
Promote, attribute, or link this skill from your own README, blog post, or documentation. All three snippets are free to use — no sign-up, no API key. More distribution surfaces →
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Security scan
Grade A · scanned 2026-07-06 — free static scan against the OWASP Agentic Skills Top 10.
No risk patterns were found in any of the ten OWASP-aligned categories. How grading works ›
- ✓ Prompt injection
- ✓ Data exfiltration
- ✓ Supply chain
- ✓ Reverse shell
- ✓ Credentials
- ✓ Execution
- ✓ Filesystem
- ✓ Persistence
- ✓ Obfuscation
- ✓ Network
Show this grade on your repo (click to copy):
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