Analyzes alternative splicing from PacBio Iso-Seq (HiFi, Kinnex/MAS-Iso-seq) and Oxford Nanopore (direct cDNA, direct RNA, R10.4.1+) long-read RNA-seq with full-isoform r — from…
Evaluates genome assembly quality across the three orthogonal axes - contiguity (QUAST auN/NG50/NGx, not bare N50), completeness (BUSCO/compleasm gene-space plus Merqury k-mer…
Access USPTO APIs for patent/trademark searches, examination history (PEDS), assignments, citations, office actions, TSDR, for IP analysis and prior art searches.
Comprehensive testing skill for GabeDA application - designs test strategies (UAT, integration, smoke, unit), creates tests for frontend (React/Playwright) and backend (D — from…
DNA methylation analysis with methylKit in R. Import Bismark coverage files, filter by coverage, normalize samples, and perform statistical comparisons.
Profiles non-miRNA small RNAs - tRNA-derived fragments (tRFs/tsRNAs), piRNAs, and rRNA/snoRNA-derived species - with MINTmap, unitas, SPORTS, and proTRAC.
When the user wants to add or optimize Open Graph metadata for social sharing. Also use when the user mentions "Open Graph," "og:tags," "og:title," "og:image," "og:description,"…
Design PCR primers for a target sequence using primer3-py. Specify target regions, product size, melting temperature, and other constraints.
Use when Codex, Hermes, OpenClaw, Claude Code, Cowork, or another AI agent needs to plan, review, implement, audit, or improve email work focused on Claude-assisted posit — from…
Taxonomic classification of metagenomic reads using Kraken2. Fast k-mer based classification against RefSeq database.
Map identified threats to appropriate security controls and mitigations. Use when prioritizing security investments, creating remediation plans, or validating control eff — from…
When the user wants to track AI search traffic in GA4 or GSC. Also use when the user mentions "AI traffic," "ChatGPT referral," "Perplexity traffic," "AI Overviews," "GA4 AI…
Deep learning-based variant calling from long reads using Clair3 for SNPs and small indels. Use when calling germline variants from ONT or PacBio alignments, particularly — from…
Dimensionality reduction and clustering for single-cell RNA-seq using Seurat (R) and Scanpy (Python).
Design homology-directed repair donor templates for CRISPR knock-ins using primer3-py. Create ssODN, dsDNA, or plasmid templates with optimized homology arms.
Joint genotype calling across multiple samples using GATK CombineGVCFs and GenotypeGVCFs. Essential for cohort studies, population genetics, and leveraging VQSR.
Use when you want to retrieve quantitative RNA expression data and variant eQTL information from the GTEx (Genotype-Tissue Expression) Project across 54 non-diseased tissue sites.
Structured manuscript/grant review with checklist-based evaluation. Use when writing formal peer reviews with specific criteria methodology assessment, statistical validi — from…
Supervised and unsupervised multi-omics integration with mixOmics. Includes sPLS for pairwise integration and DIABLO for multi-block discriminant analysis.
Generate text-to-video with Wan 2.7 (Wan-AI's flagship motion model) on RunComfy. Documents Wan 2.7's strengths (multi-reference conditioning, audio-driven lip-sync via ` — from…
When the user wants to choose or optimize rendering strategy for SEO. Also use when the user mentions "SSR," "SSG," "CSR," "ISR," "static rendering," "dynamic rendering,"…
End-to-end post-GWAS causal inference pipeline orchestrating heritability partitioning, genetic correlation, Mendelian randomization with CHP-aware sensitivity (CAUSE / L — from…
Retrieves gene expression and omics datasets from ArrayExpress and BioStudies with gene disambiguation, experiment quality assessment, and structured reports.
Build automated AI workflows combining multiple models and services. Patterns: batch processing, scheduled tasks, event-driven pipelines, agent loops.
Optimize Bazel builds for large-scale monorepos. Use when configuring Bazel, implementing remote execution, or optimizing build performance for enterprise codebases.
Calculates molecular fingerprints (ECFP/Morgan, FCFP, MACCS, RDKit, AtomPair, TopologicalTorsion, Avalon, MAP4, MHFP6) and physicochemical descriptors (Lipinski, QED, TPSA,…
Create AI avatar and talking head videos via inference.sh CLI. Recommended: P-Video-Avatar (fastest, cheapest, built-in TTS). Also: OmniHuman, Fabric, PixVerse.
Daily inbox triage using Cowork's email write tools (Microsoft 365 or Gmail) -- classifies unread mail, drafts replies in your voice, flags what needs a decision, and schedules…
Build production 1:1 stablecoin swaps with LI.FI Intents, where the amount sent equals the amount received with no visible gas or solver fees, on the same chain or across chains.
OKX-aggregated DeFi (no specific DApp named) — product discovery, deposit/withdraw/claim execution, AND positions viewing.
Perform V(D)J alignment and clonotype assembly from TCR-seq or BCR-seq data using MiXCR. Use when processing raw immune repertoire sequencing data to identify clonotypes — from…
Build genome-browser-style multi-track figures with pyGenomeTracks (config-driven), Gviz (R), and IGV batch screenshotting.
Comprehensive systems biology and pathway analysis using multiple pathway databases (Reactome, KEGG, WikiPathways, Pathway Commons, BioModels).
Modify protein structures using Biopython Bio.PDB. Use when transforming coordinates, removing atoms or residues, adding new entities, modifying B-factors and occupancies — from…
Agile product ownership toolkit for Senior Product Owner including INVEST-compliant user story generation, sprint planning, backlog management, and velocity tracking.
Use when analyzing binary structure, disassembling code, or decompiling functions. Deep static analysis via radare2 (r2) and Ghidra headless - function enumeration, cross — from…
Graph Neural Networks (PyG). Node/graph classification, link prediction, GCN, GAT, GraphSAGE, heterogeneous graphs, molecular property prediction, for geometric deep lear — from…
Comprehensive document creation, editing, and analysis with support for tracked changes, comments, formatting preservation, and text extraction.
Identifies super-enhancers from H3K27ac ChIP-seq data using ROSE and related tools. Use when studying cell identity genes, cancer-associated regulatory elements, or master…
Statistical testing for differentially abundant proteins between conditions. Covers limma and MSstats workflows with multiple testing correction.
Build interactive HTML/web visualizations with plotly (Python/R), bokeh (Python), and gganimate/plotly frames for animation, with awareness of current Kaleido static-export model…
Estimates circulating tumor DNA fraction from shallow whole-genome sequencing using ichorCNA. Detects copy number alterations via HMM segmentation and calculates ctDNA pe — from…
Calculates molecular descriptors and fingerprints using RDKit. Computes Morgan fingerprints (ECFP), MACCS keys, Lipinski properties, QED drug-likeness, TPSA, and 3D conformer…
Predict protein structures using modern ML models including AlphaFold3, ESMFold, Chai-1, and Boltz-1.
Sweep your folders and downloads for tax documents and build a CPA-ready package -- checklist by form type, everything renamed and organized, a missing-document chase list, and…
Run 150+ AI apps via inference.sh CLI - image generation, video creation, LLMs, search, 3D, Twitter automation.
Generate AI images with FLUX, Gemini, Grok, Seedream, Reve and 50+ models via inference.sh CLI. Models: FLUX Dev LoRA, FLUX.2 Klein LoRA, Gemini 3 Pro Image, Grok Imagine — from…
Analyzes alternative splicing at single-cell resolution. The first decision is library chemistry — 10X 3' is fundamentally limited (RT primes from poly-A, R2 falls in 3' UTR, <0.1…
Production-ready microscopy image analysis and quantitative imaging data skill for colony morphometry, cell counting, fluorescence quantification, and statistical analysis of…
Guide users through a structured workflow for co-authoring documentation. Use when user wants to write documentation, proposals, technical specs, decision docs, or simila — from…
Executive leadership guidance for strategic decision-making, organizational development, and stakeholder management.
Create AI avatar and talking head videos via inference.sh CLI. Recommended: P-Video-Avatar (fastest, cheapest, built-in TTS). Also: OmniHuman, Fabric, PixVerse.
Use when you have a spec or requirements for a multi-step task, before touching code — from bg-szy/TOP-SKILLS
Discover novel small molecule binders for protein targets using structure-based and ligand-based approaches.
Automatically creates user-facing changelogs from git commits by analyzing commit history, categorizing changes, and transforming technical commits into clear, customer-f — from…
Map nucleosome center positions, occupancy, and fuzziness from ATAC-seq fragment-size patterns using NucleoATAC, ATACseqQC, DANPOS3, or scprinter.
When the user wants to create or optimize a refund or return policy page. Also use when the user mentions "refund policy," "return policy," "money-back guarantee," "returns and…
Convert text to speech audio using OpenAI TTS-1-HD through the verging.ai proxy API. Supports multiple voices, playback speed control, and various audio output formats.
Generate consensus FASTA sequences by applying VCF variants to a reference using bcftools consensus. Use when creating sample-specific reference sequences or reconstructi — from…
Guides creation of effective Agent Skills with proper structure and validation. Use when users want to create a new skill, update an existing skill, or need guidance on s — from…