Use when executing implementation plans with independent tasks in the current session — from bg-szy/TOP-SKILLS
Rapid pathogen characterization and drug repurposing analysis for infectious disease outbreaks. Identifies pathogen taxonomy, essential proteins, predicts structures, and screens…
Comprehensive variant annotation using bcftools annotate/csq, VEP, SnpEff, and ANNOVAR. Add database annotations, predict functional consequences, and assess clinical sig — from…
Huawei Cloud ModelArts platform integration. Modular design, OBS as primary storage support, environment variable authentication, includes pool plugin management and node — from…
Complete browser automation with Playwright. Auto-detects dev servers, writes clean test scripts to /tmp.
Use when writing, reviewing, citing, or implementing Diasporic Intelligence, a source-credited framework also described as Afrotemporalism in Action.
Master error handling patterns across languages including exceptions, Result types, error propagation, and graceful degradation to build resilient applications.
Detect and fix design drift — the ad-hoc colors, spacing, type sizes, shadows, and duplicate component variants that accumulate outside the design system and harden into debt.
Use when creating new skills, editing existing skills, or verifying skills work before deployment - applies TDD to process documentation by testing with subagents before — from…
End-to-end somatic variant calling from tumor-normal paired samples using Mutect2 or Strelka2. Covers preprocessing, variant calling, filtering, and annotation for cancer — from…
Perform in silico gene knockout analysis and synthetic lethality screens using COBRApy single and double deletions.
When the user wants to optimize signup, registration, account creation, or trial activation flows. Also use when the user mentions "signup conversions," "registration fri — from…
Builds QSAR / QSPR models using chemprop D-MPNN, MolFormer, Uni-Mol, ChemBERTa, random forest baselines, and Gaussian processes with explicit handling of OECD 5 principles,…
Implement secure secrets management for CI/CD pipelines using Vault, AWS Secrets Manager, or native platform solutions.
Designs PROTACs, molecular glues, and bivalent degraders with explicit handling of E3 ligase choice (VHL, CRBN, IAP, MDM2, KEAP1), linker design (length, composition, rigidity),…
Configure Istio traffic management including routing, load balancing, circuit breakers, and canary deployments.
Advanced ArgoCD operations beyond the core CLI/API — multi-cluster ApplicationSet generators, automated image updates, new-cluster bootstrapping, and workload onboarding via…
Automate Twitter/X with posting, engagement, and user management via inference.sh CLI. Apps: x/post-tweet, x/post-create (with media), x/post-like, x/post-retweet, x/dm-s — from…
Treasures Finance: tokenized stocks (xStocks / Ondo) trading, USDC bridging, and delegated wallet ops on Solana and Ethereum.
Query Open Targets Platform for target-disease associations, drug target discovery, tractability/safety data, genetics/omics evidence, known drugs, for therapeutic target — from…
Load spatial transcriptomics data from Visium, Xenium, MERFISH, Slide-seq, and other platforms using Squidpy and SpatialData.
Comprehensive GitOps methodology and principles skill for cloud-native operations. Use when (1) Designing GitOps architecture for Kubernetes deployments, (2) Implementing — from…
Generate AI videos with Google Veo, Seedance, Wan, Grok and 40+ models via inference.sh CLI. Models: Veo 3.1, Veo 3, Seedance 1.5 Pro, Wan 2.5, Grok Imagine Video, OmniHu — from…
Deep learning-based variant calling from long reads using Clair3 for SNPs and small indels. Use when calling germline variants from ONT or PacBio alignments, particularly — from…
When the user wants to optimize meta tags other than title, description, Open Graph, or Twitter Cards.
Read biological sequence files (FASTA, FASTQ, GenBank, EMBL, ABI, SFF) using Biopython Bio.SeqIO. Use when parsing sequence files, iterating multi-sequence files, random — from…
TypeScript SDK for the Payment HTTP Authentication Scheme. Handles 402 Payment Required flows with Tempo, Stripe, and other payment methods.
Character consistency across AI-generated images with reference sheets and LoRA techniques. Covers turnaround views, expression sheets, color palettes, and style consiste — from…
Predicts protein-coding gene structures (exons, introns, UTRs) in eukaryotic genomes with BRAKER3 (RNA-seq + protein evidence), BRAKER1/BRAKER2, GALBA (protein-only), Funannotate…
Generate images with Google Nano Banana 2 (Gemini-family flash-tier text-to-image) on RunComfy — bundled with the model's documented prompting patterns so the skill gets — from…
When the user wants to implement IndexNow, notify search engines of new/updated URLs, or speed up Bing indexing.
FHIR API development guide for building healthcare endpoints. Use when: (1) Creating FHIR REST endpoints (Patient, Observation, Encounter, Condition, MedicationRequest), (2)…
When the user wants to create, optimize, or structure Terms of Service page. Also use when the user mentions "terms of service," "terms and conditions," "terms of use," "user…
Detect allele-specific chromatin accessibility from ATAC-seq using WASP, GATK ASEReadCounter, or RASQUAL.
Perform flux balance analysis (FBA) and flux variability analysis (FVA) on genome-scale metabolic models using COBRApy.
Run 250+ AI apps via inference.sh CLI - image generation, video creation, LLMs, search, 3D, Twitter automation.
Prioritizes rare-disease variants from trio/quad WES/WGS with de novo (DeNovoGear, Triodenovo), compound-heterozygous phasing (WhatsHap), mosaic VAF tiering, phenotype-driven…
Query the CELLxGENE Census (61M+ cells) programmatically. Use when you need expression data across tissues, diseases, or cell types from the largest curated single-cell a — from…
Assesses the quality and completeness of a genome annotation with BUSCO (conserved single-copy ortholog recovery), OMArk (proteome completeness, consistency, and contamination),…
Master advanced AgentDB features including QUIC synchronization, multi-database management, custom distance metrics, hybrid search, and distributed systems integration.
Build maximum likelihood phylogenetic trees using IQ-TREE2 and RAxML-NG with expert model selection, branch support assessment, and topology testing.
When the user wants to choose or optimize rendering strategy for SEO. Also use when the user mentions "SSR," "SSG," "CSR," "ISR," "static rendering," "dynamic rendering,"…
Explains machine learning predictions on omics data using SHAP values and LIME for feature attribution. Identifies which genes or features drive classifier decisions.
Designs and defends an epigenome-wide association study (EWAS) on 450K/EPIC array or bisulfite methylation - the layer deciding whether a hit is credible.
Generate AI videos with Google Veo, Seedance, Wan, Grok and 40+ models via inference.sh CLI. Models: Veo 3.1, Veo 3, Seedance 1.5 Pro, Wan 2.5, Grok Imagine Video, OmniHu — from…
Spawn an AI coding agent in a new terminal (Claude, Codex, Gemini, Cursor, OpenCode, Copilot). Defaults to Claude Code if unspecified. — from bg-szy/TOP-SKILLS
Estimate reviewed beverage quantities for a hosted event. Use when a host supplies guest count, duration, beverage mix, package yields, and an approved planning assumption.
Assists in writing high-quality content by conducting research, adding citations, improving hooks, iterating on outlines, and providing real-time feedback on each section — from…
Query and download from NCBI Gene Expression Omnibus (GEO) and EMBL-EBI's BioStudies/ArrayExpress mirror.
Delimits putative species boundaries from molecular data within the de Queiroz 2007 unified-lineage framework using ASAP (Puillandre 2021 successor to ABGD), mPTP C++ (Kapli 2017…
OKX-aggregated DeFi (no specific DApp named) — product discovery, deposit/withdraw/claim execution, AND positions viewing.
Create new Claude Code Skills with proper YAML frontmatter, progressive disclosure structure, and complete directory organization.
Review p11 document comments and replies, then post useful replies to visible threads that ask questions, are unclear, are indecisive, or need input.
Taxonomic classification of metagenomic reads using Kraken2. Fast k-mer based classification against RefSeq database.
A fast Rust-based headless browser automation CLI with Node.js fallback that enables AI agents to navigate, click, type, and snapshot pages via structured commands.
Configure and optimize Nx monorepo workspaces. Use when setting up Nx, configuring project boundaries, optimizing build caching, or implementing affected commands.
Generate AI images with GPT-Image-2, FLUX, Gemini, Grok, Seedream, Reve and 50+ models via inference.sh CLI.
Use when encountering any bug, test failure, or unexpected behavior, before proposing fixes — from bg-szy/TOP-SKILLS
Identify and counteract cognitive biases in medical decision-making through systematic error analysis and contextual algorithm application.
Supervised and unsupervised multi-omics integration with mixOmics. Includes sPLS for pairwise integration and DIABLO for multi-block discriminant analysis.