Performs gene-level association from GWAS summary statistics via genetically predicted tissue expression using FUSION, PrediXcan, S-PrediXcan, S-MultiXcan, UTMOST, MOSTWAS, kTWAS,…
MS-DIAL-based metabolomics preprocessing as alternative to XCMS. Covers peak detection, alignment, annotation, and export for downstream analysis.
Predict TCR-epitope specificity using ERGO-II and deep learning models for T-cell receptor antigen recognition.
Implement the minimal code needed to make failing tests pass in the TDD green phase. — from bg-szy/TOP-SKILLS
Use when completing tasks, implementing major features, or before merging to verify work meets requirements — from bg-szy/TOP-SKILLS
Break a plan, spec, or the current conversation into a set of tracer-bullet tickets, each declaring its blocking edges, published to the configured tracker — edges as tex — from…
Toolkit for interacting with and testing local web applications using Playwright. Supports verifying frontend functionality, debugging UI behavior, capturing browser scre — from…
Implements authentication and payment features using Clerk, Supabase Auth, or Stripe. Use when user mentions ログイン, 認証, auth, authentication, Clerk, Supabase, 決済, payment, Stripe,…
Impute missing genotypes using reference panels with Beagle or Minimac4. Use when increasing variant density for GWAS, harmonizing data across genotyping platforms, or in — from…
View, query, and understand VCF/BCF variant files using bcftools and cyvcf2. Use when inspecting variants, extracting specific fields, or understanding VCF format structu — from…
Publication-quality visualizations for biomedical and genomics data. Use when creating volcano plots, heatmaps, UMAP plots, dot plots, survival curves, forest plots, or…
Bisulfite sequencing read alignment using Bismark with bowtie2/hisat2. Handles genome preparation and produces BAM files with methylation information.
Maps between gene identifier systems (Ensembl, Entrez, HGNC symbol, UniProt, RefSeq, MANE) using AnnotationDbi, biomaRt, mygene, pyensembl, and Ensembl REST.
Calculate tumor mutational burden from panel or WES data with proper normalization and clinical thresholds.
Presentation toolkit (.pptx). Create/edit slides, layouts, content, speaker notes, comments, for programmatic presentation creation and modification. — from bg-szy/TOP-SKILLS
Quality control of phasing and imputation results. Filter by INFO scores, assess accuracy, and prepare imputed data for downstream analysis.
Intelligently organizes files and folders by understanding context, finding duplicates, and suggesting better organizational structures.
All-in-one read preprocessing with fastp including adapter trimming, quality filtering, deduplication, base correction, and HTML report generation.
Profiles a genome from raw reads BEFORE assembly with a k-mer spectrum (KMC or Jellyfish histogram), then models it with GenomeScope2 to estimate genome size, heterozygosity,…
Detect sample contamination and cross-species reads using FastQ Screen. Screen reads against multiple reference genomes to identify bacterial, viral, adapter, or sample s — from…
Generate images with Google Nano Banana 2 (Gemini-family flash-tier text-to-image) on RunComfy — bundled with the model's documented prompting patterns so the skill gets — from…
Render videos from React/Remotion component code via inference.sh. Pass TSX code, get MP4. Supports all Remotion APIs: useCurrentFrame, useVideoConfig, spring, interpolat — from…
Master dbt (data build tool) for analytics engineering with model organization, testing, documentation, and incremental strategies.
Senior Quality Documentation Manager for comprehensive documentation control and regulatory document review.
When the user wants to optimize signup, registration, account creation, or trial activation flows. Also use when the user mentions "signup conversions," "registration fri — from…
Analyzes spatial proteomics data from CODEX, IMC, and MIBI platforms including cell segmentation and protein colocalization.
Suite of tools for creating elaborate, multi-component claude.ai HTML artifacts using modern frontend web technologies (React, Tailwind CSS, shadcn/ui).
Build production React Native apps with Expo, navigation, native modules, offline sync, and cross-platform patterns.
Audit, revise, or draft manuscript statistical reporting for Nature / high-impact journal submissions.
Python population genetics with scikit-allel. Read VCF files, compute allele frequencies, calculate diversity statistics, perform PCA, and run selection scans using Genot — from…
Build or modernize an employee handbook for a small business with no HR department -- interviews the owner for actual practices, drafts every core policy in plain English, flags…
Guide for creating high-quality MCP (Model Context Protocol) servers that enable LLMs to interact with external services through well-designed tools.
Implement comprehensive testing strategies with pytest, fixtures, mocking, and test-driven development.
Designs PROTACs, molecular glues, and bivalent degraders with explicit handling of E3 ligase choice (VHL, CRBN, IAP, MDM2, KEAP1), linker design (length, composition, rigidity),…
Access NIH Metabolomics Workbench via REST API (4,200+ studies). Query metabolites, RefMet nomenclature, MS/NMR data, m/z searches, study metadata, for metabolomics and b — from…
When the user wants to create, optimize, or audit a showcase or gallery page for user-generated content.
Upload approved local HTML, markdown, or image assets to a Stitch project using direct MCP for small DESIGN.md files or the bundled API script for larger files.
Presentation creation, editing, and analysis. When Claude needs to work with presentations (.pptx files) for: (1) Creating new presentations, (2) Modifying or editing con — from…
Predict peptide-MHC class II (HLA-DR/DQ/DP) binding and presentation for CD4 T-cell epitopes with NetMHCIIpan-4.3 and MixMHC2pred-2.0.
Redesign or QA PDFs for clarity while preserving IDs, dates, amounts, barcodes, QR codes, seals, signatures, labels, and meaning.
Smart dependency management for any language. Auto-detects project type, applies safe updates automatically, prompts for major versions, diagnoses and fixes dependency issues.
Publish Markdown articles to X (Twitter) Articles editor with proper formatting. Use when user wants to publish a Markdown file/URL to X Articles, or mentions "publish to — from…
Perform in silico gene knockout analysis and synthetic lethality screens using COBRApy single and double deletions.
飞书视频会议：让机器人代当前用户加入/离开正在进行的会议，并读取会议期间的实时事件（参会人加入与离开、发言、聊天、屏幕共享等）。1. 用户提供 9 位会议号、要求代为入会或离会时使用 +meeting-join / +meeting-leave——会真实产生入会/离会记录。2.
When the user wants to optimize for Featured Snippets, Position Zero, or snippet extraction. Also use when the user mentions "featured snippet," "position zero," "snippet…
Designs adaptive clinical trials including group-sequential (O'Brien-Fleming, Pocock, Lan-DeMets spending), sample-size re-estimation (blinded Friede-Kieser, unblinded Cu — from…
Generate AI images with GPT-Image-2, FLUX, Gemini, Grok, Seedream, Reve and 50+ models via inference.sh CLI.
Quantifies alternative splicing as PSI (percent spliced in) from RNA-seq using rMATS-turbo (BAM-based event), SUPPA2 (TPM-based event), MAJIQ V3 (LSV-based Bayesian), leafcutter…
Reconstruct cell lineage trees from CRISPR barcode tracing or mitochondrial mutations. Use when studying clonal dynamics, cell fate decisions, or developmental trajectori — from…
Read and write compressed sequence files (gzip, bzip2, BGZF) using Biopython. Use when working with .gz or .bz2 sequence files. Use BGZF for indexable compressed files.
UpdateStock MCP 服务技能 —— 通过 stdio 模式调用 UpdateStock 脚本， 提供 A 股 DuckDB 数据库管理功能：创建数据库、全量/增量更新股票数据、查询股票行情。 设计的数据库方案兼容 QuantAll（全A解析）计算引擎。…
Analyzes cfDNA methylation patterns for cancer detection using cfMeDIP-seq or bisulfite sequencing with MethylDackel.
Spawn an AI coding agent in a new terminal (Claude, Codex, Gemini, Cursor, OpenCode, Copilot). Defaults to Claude Code if unspecified. — from bg-szy/TOP-SKILLS
Use when starting feature work that needs isolation from current workspace or before executing implementation plans - creates isolated git worktrees with smart directory — from…
Create, revise, polish, inspect, export, and preview complete stylized Roblox R6 and R15 character animations on authentic Studio-derived Blender rigs through MCP.
Implement Kubernetes security policies including NetworkPolicy, PodSecurityPolicy, and RBAC for production-grade security.
AgentLink gives an AI agent a verified, human-backed on-chain identity. Use it to link and register an agent wallet with a biomapped human owner in BiomapperAgentRegistry — from…
Web search and content extraction with Tavily and Exa via inference.sh CLI. Apps: Tavily Search, Tavily Extract, Exa Search, Exa Answer, Exa Extract.
Analyze metabolite-mediated cell-cell communication using MeboCost for metabolic signaling inference between cell types.
macOS development environment setup wizard. Interactive Q&A to collect preferences, auto-detect installed software, generate customized installation plan.