Query PubChem, search by name/CID/SMILES, retrieve properties, similarity/substructure searches, bioactivity, for cheminformatics.
Comprehensive toolkit for product managers including RICE prioritization, customer interview analysis, PRD templates, discovery frameworks, and go-to-market strategies.
Landing page conversion optimization with layout rules, hero section design, and CTA psychology. Covers above-the-fold formula, social proof placement, mobile design, and…
When the user wants to optimize for mobile-first indexing or fix mobile usability. Also use when the user mentions "mobile-friendly," "mobile-first indexing," "mobile SEO,"…
Create and manage production Grafana dashboards for real-time visualization of system and application metrics.
Pay-per-call access to the Nansen API via MPP (Tempo). Use when a user wants anonymous Nansen access without an API key and without managing their own Base/Solana wallet — from…
Compute HEIM diversity and equity metrics from VCF or ancestry data. Generates heterozygosity, FST, PCA plots, and a composite HEIM Equity Score with markdown reports.
Add p-value brackets, significance asterisks, and effect-size annotations to distribution plots using ggpubr, ggsignif, and statannotations with correct test selection (parametric…
Document toolkit (.docx). Create/edit documents, tracked changes, comments, formatting preservation, text extraction, for professional document processing. — from bg-szy/TOP-SKILLS
Analyze single-cell TCR and BCR data integrated with gene expression using scirpy. Use when working with 10x Genomics VDJ data alongside scRNA-seq or when integrating imm — from…
Master Unity ECS (Entity Component System) with DOTS, Jobs, and Burst for high-performance game development.
Use when starting feature work that needs isolation from current workspace or before executing implementation plans - creates isolated git worktrees with smart directory — from…
Guide users through creating Agent Skills for Claude Code. Use when the user wants to create, write, author, or design a new Skill, or needs help with SKILL.md files, fro — from…
Quality control and assessment for proteomics data. Use when evaluating proteomics data quality before downstream analysis.
Interactive cell type annotation for IMC data. Covers napari-based annotation, marker-guided labeling, training data generation, and annotation validation.
Guided statistical analysis with test selection and reporting. Use when you need help choosing appropriate tests for your data, assumption checking, power analysis, and A — from…
Quantifies biodiversity from species abundance/incidence tables using Hill numbers (iNEXT) with coverage-based rarefaction-extrapolation (Chao & Jost 2012), asymptotic richness…
Sequence-based deep learning for ATAC-seq using chromBPNet, BPNet, scBasset, or EnFormer. Use when correcting Tn5 bias with neural networks beyond k-mer models, predicting…
Analyzes alternative splicing at single-cell resolution using BRIE2 for probabilistic PSI estimation or leafcutter2 for cluster-based analysis with NMD detection.
MS-DIAL-based metabolomics preprocessing as alternative to XCMS. Covers peak detection, alignment, annotation, and export for downstream analysis.
Review the changes since a fixed point (commit, branch, tag, or merge-base) along two axes — Standards (does the code follow this repo's documented coding standards?) and — from…
Machine learning in Python with scikit-learn. Use when working with supervised learning (classification, regression), unsupervised learning (clustering, dimensionality re — from…
Creating algorithmic art using p5.js with seeded randomness and interactive parameter exploration. Use this when users request creating art using code, generative art, al — from…
Profile functional potential of metagenomes using HUMAnN3 and similar tools. Use when obtaining pathway abundances, gene family counts, or functional annotations from met — from…
Automatically reviews DevPrep AI code for quality standards including ESLint compliance, TypeScript strict mode, 180-line file limits, complexity under 15, proper naming…
Use for explicit undergraduate data-science teaching, assignment guidance, concept clarification, method selection, or output interpretation.
Use when creating new skills, editing existing skills, or verifying skills work before deployment — from bg-szy/TOP-SKILLS
Runs cis-pQTL Mendelian randomization for drug-target validation using UKB-PPP (Olink), deCODE (SomaScan), Fenland, INTERVAL, ARIC, and FinnGen-PPP proteomes plus colocal — from…
Build circular genome visualizations using circlize (R), pyCirclize (Python), or Circos (Perl CLI) with ideogram tracks, multi-data tracks (scatter, histogram, heatmap),…
Visualize metagenomic profiles using R (phyloseq, microbiome) and Python (matplotlib, seaborn). Create stacked bar plots, heatmaps, PCA plots, and diversity analyses.
Use when reverse engineering tools are missing, not working, or need configuration. Installation guides for radare2 (r2), Ghidra, GDB, QEMU, Frida, binutils, and cross-co — from…
Refresh a repo's documentation for a live production system — audit stale docs, rebuild a focused doc set with diagrams, update AI-agent knowledge bases, and improve code-level…
Scaffold a new Open Knowledge Format (OKF) knowledge base and populate it from existing material: a tree of small markdown concept files with YAML frontmatter, a spec, a…
CRISPResso2 for analyzing CRISPR gene editing outcomes. Quantifies indels, HDR efficiency, and generates comprehensive editing reports.
Guide Claude through SCSA, MetaTiME, CellVote, CellMatch, GPTAnno, and weighted KNN transfer workflows for annotating single-cell modalities. — from bg-szy/TOP-SKILLS
Comprehensive molecular biology toolkit. Use for sequence manipulation, file parsing (FASTA/GenBank/PDB), phylogenetics, and programmatic NCBI/PubMed access (Bio.Entrez) — from…
Official skill for integrating Firebase AI Logic (Gemini API) into web applications. Covers setup, multimodal inference, structured output, and security. — from bg-szy/TOP-SKILLS
Generate AI videos with Google Veo, Seedance, Wan, Grok and 40+ models via inference.sh CLI. Models: Veo 3.1, Veo 3, Seedance 1.5 Pro, Wan 2.5, Grok Imagine Video, OmniHu — from…
When the user wants to add, optimize, or audit table of contents (TOC) for long-form content. Also use when the user mentions "TOC," "table of contents," "table of contents for…
Identify differentially accessible chromatin regions across conditions using DiffBind, csaw, DESeq2, or edgeR.
Design pegRNAs for prime editing using PrimeDesign algorithms. Generate spacer, PBS, and RT template sequences for precise genomic modifications without double-strand breaks.
Standardizes molecular structures using ChEMBL chembl_structure_pipeline and RDKit rdMolStandardize covering sanitization, salt/solvent stripping, neutralization, tautome — from…
Technical leadership guidance for engineering teams, architecture decisions, and technology strategy.
Predict enhancer-gene regulatory connections from ATAC-seq using ABC, ENCODE-rE2G, HiChIP, or Cicero.
Calculate immune repertoire diversity metrics, compare samples, and track clonal dynamics using VDJtools.
Maps query single-cell data to reference atlases using scArches transfer learning with scVI and scANVI models.
Generate AI images with FLUX, Gemini, Grok, Seedream, Reve and 50+ models via inference.sh CLI. Models: FLUX Dev LoRA, FLUX.2 Klein LoRA, Gemini 3 Pro Image, Grok Imagine — from…
Use when Codex, Hermes, OpenClaw, Claude Code, Cowork, or another AI agent needs to plan, review, implement, audit, or improve email work focused on fast delivery decisio — from…
Production-ready phylogenetics and sequence analysis skill for alignment processing, tree analysis, and evolutionary metrics.
Reconstruct cell lineage trees from CRISPR barcode tracing or mitochondrial mutations. Use when studying clonal dynamics, cell fate decisions, or developmental trajectori — from…
Generate AI videos with Google Veo, Seedance, Wan, Grok and 40+ models via inference.sh CLI. Models: Veo 3.1, Veo 3, Seedance 1.5 Pro, Wan 2.5, Grok Imagine Video, OmniHu — from…
Point Cowork at your invoices and payments records -- builds an AR aging report, drafts escalating follow-up emails matched to each invoice's age and the client relationship, and…
Scoring framework for test-kitchen cookoff and omakase-off. Invoked at Phase 4 to evaluate implementations using 5-criteria scoring.
Build automated AI workflows combining multiple models and services. Patterns: batch processing, scheduled tasks, event-driven pipelines, agent loops.
Tactical user interface design guide for fixing layouts, selecting colors and fonts, and creating professional UIs.
Guide for creating Claude Code skills following Anthropic's official best practices. Use when user wants to create a new skill, build a skill, write SKILL.md, or needs sk — from…
World-class data science skill for statistical modeling, experimentation, causal inference, and advanced analytics.
Comprehensive research assistant that synthesizes information from multiple sources with citations. Use when: conducting in-depth research, gathering sources, writing research…
Daily inbox triage using Cowork's email write tools (Microsoft 365 or Gmail) -- classifies unread mail, drafts replies in your voice, flags what needs a decision, and schedules…
Extract content from specific URLs using Tavily's extraction API. Returns clean markdown/text from web pages.