Creates new Claude Code skills following best practices. Guides through skill structure, naming, descriptions, and progressive disclosure.
Quantifies biodiversity from species abundance/incidence tables using Hill numbers (iNEXT) with coverage-based rarefaction-extrapolation (Chao & Jost 2012), asymptotic richness…
Turns raw Illumina Infinium methylation BeadChip IDATs (450K, EPIC, EPICv2) into a defensible beta/M matrix with sesame (openSesame/SigDF) or minfi (RGChannelSet -> MethylSet ->…
Master ShellCheck static analysis configuration and usage for shell script quality. Use when setting up linting infrastructure, fixing code issues, or ensuring script por — from…
Automate Twitter/X with posting, engagement, and user management via inference.sh CLI. Apps: x/post-tweet, x/post-create (with media), x/post-like, x/post-retweet, x/dm-s — from…
Calculate alignment statistics including sequence identity, conservation scores, substitution matrices, and similarity metrics.
Builds QSAR / QSPR models using chemprop D-MPNN, MolFormer, Uni-Mol, ChemBERTa, random forest baselines, and Gaussian processes with explicit handling of OECD 5 principles,…
Detects spatially variable genes, spatial autocorrelation, and cell-type colocalization for spatial transcriptomics using Squidpy with PySAL/esda for local statistics.
Use when receiving code review feedback, before implementing suggestions, especially if feedback seems unclear or technically questionable - requires technical rigor and — from…
Post-translational modification analysis including phosphorylation, acetylation, and ubiquitination. Covers site localization, motif analysis, and quantitative PTM analys — from…
Design a PostgreSQL-specific schema. Covers best-practices, data types, indexing, constraints, performance patterns, and advanced features — from bg-szy/TOP-SKILLS
Orchestrates an end-to-end MeRIP-seq / m6A-seq analysis from raw FASTQ to differential m6A peak calls and metagene plots, chaining fastp adapter trimming, STAR splice-aware genome…
Verify whether an image or video is authentic, original and correctly captioned — provenance checks, error level analysis, noise and JPEG compression analysis, clone and copy-move…
Build local BLAST databases and run searches using NCBI BLAST+ command-line tools. Use when running >50 queries, building custom databases with -parse_seqids and -taxid,…
Search global patents with natural language queries. Prior art, patent landscapes, and innovation tracking via Valyu.
Tests associations between categorical variables in clinical data using chi-square, Fisher's exact, Boschloo, Cochran-Mantel-Haenszel, and modern McNemar variants with calibrated…
AI video generation for agents through Image Skill's zero-setup hosted creative runtime. Use when a prompt should become a durable hosted video without provider credentials,…
Browser automation for AI agents via inference.sh. Navigate web pages, interact with elements using @e refs, take screenshots, record video.
Toolkit for interacting with and testing local web applications using Playwright. Supports verifying frontend functionality, debugging UI behavior, capturing browser scre — from…
Calls DNA methylation from Oxford Nanopore sequencing data using signal-level analysis. Use when detecting 5mC or 6mA modifications directly from nanopore reads without b — from…
Call protein-RNA binding sites from CLIP-seq BAM with CLIPper, PureCLIP, Skipper, Piranha, omniCLIP, CTK, CLAM, or Paraclu.
Comprehensive molecular biology toolkit. Use for sequence manipulation, file parsing (FASTA/GenBank/PDB), phylogenetics, and programmatic NCBI/PubMed access (Bio.Entrez) — from…
Build a source-grounded deep-reading Paper Card for one scientific paper, preprint, PDF, DOI, arXiv page, publisher article, or pasted paper text.
Comprehensive structural variant (SV) analysis skill for clinical genomics. Classifies SVs (deletions, duplications, inversions, translocations), assesses pathogenicity using…
Design novel protein therapeutics (binders, enzymes, scaffolds) using AI-guided de novo design. Uses RFdiffusion for backbone generation, ProteinMPNN for sequence design,…
Huawei Cloud ModelArts platform integration. Modular design, OBS as primary storage support, environment variable authentication, includes pool plugin management and node — from…
Develop AI-powered applications using Genkit in Node.js/TypeScript. Use when the user asks about Genkit, AI agents, flows, or tools in JavaScript/TypeScript, or when enco — from…
Run Bayesian phylogenetic analysis with MrBayes, BEAST2, RevBayes, and PhyloBayes including MCMC convergence diagnostics and model comparison.
Design, organize, and manage Helm charts for templating and packaging Kubernetes applications with reusable configurations.
Count reads per gene from aligned BAM files using Subread featureCounts. Use when processing BAM files from STAR/HISAT2 to generate gene-level counts for DESeq2/edgeR.
Product marketing, positioning, GTM strategy, and competitive intelligence. Includes ICP definition, April Dunford positioning methodology, launch playbooks, competitive — from…
Genomic file toolkit. Read/write SAM/BAM/CRAM alignments, VCF/BCF variants, FASTA/FASTQ sequences, extract regions, calculate coverage, for NGS data processing pipelines.
Query dbSNP for rsID lookups, variant annotations, and cross-references to other databases. Use when mapping between rsIDs and genomic coordinates or retrieving basic var — from…
Alpha and beta diversity analysis for microbiome data. Calculate within-sample richness, evenness, and between-sample dissimilarity with phyloseq and vegan.
Measures geometric properties of protein structures with Biopython Bio.PDB - interatomic distances, distance matrices, bond and dihedral angles (phi/psi/chi, Ramachandran),…
Generate cinematic short-form video with ByteDance Seedance 2.0 Pro on RunComfy. Documents Seedance 2.0 Pro's strengths (multi-modal references — up to 9 images, 3 videos — from…
squirrelscan audits websites for SEO, performance, security, accessibility, content, and structured data issues (249+ rules) and scores site health, via the squirrel CLI.
Decides whether and how to polish a draft genome assembly to raise consensus accuracy (QV) with read-type-matched tools - Racon and medaka (ONT consensus), dorado polish,…
Help developers write code that interacts with Alkahest escrow contracts using the TypeScript, Rust, or Python SDK — from bg-szy/TOP-SKILLS
Advanced GitHub Actions workflow automation with AI swarm coordination, intelligent CI/CD pipelines, and comprehensive repository management — from bg-szy/TOP-SKILLS
Shell history management with Atuin. Use when configuring shell history, setting up history sync, searching command history, importing history from other shells, troubleshooting…
HARD BLOCK — never use for prediction-market/Polymarket UpDown queries; route to okx-dapp-discovery when a named DApp (Polymarket/Aave/Hyperliquid/PancakeSwap/Morpho) app — from…
Use when Codex, Hermes, OpenClaw, Claude Code, Cowork, or another AI agent needs to plan, review, implement, audit, or improve email work focused on time-based nurture st — from…
Custom test patterns and fixtures for {project}. Covers E2E, integration, and specialized testing requirements. — from bg-szy/TOP-SKILLS
Convert files and office documents to Markdown. Supports PDF, DOCX, PPTX, XLSX, images (with OCR), audio (with transcription), HTML, CSV, JSON, XML, ZIP, YouTube URLs, EP — from…
Compares how a rhythm CHANGES between conditions, genotypes, treatments, tissues, or ages (differential rhythmicity), classifying each feature as gain-of-rhythm, loss-of-rhythm,…
Trim multiple sequence alignments using ClipKIT, trimAl, BMGE, Divvier, or HMMcleaner with mode selection guidance per downstream goal.
Master Flutter development with Dart 3, advanced widgets, and multi-platform deployment. — from bg-szy/TOP-SKILLS
Navigate protein structure hierarchy using Biopython Bio.PDB SMCRA model. Use when accessing models, chains, residues, and atoms, iterating over structure levels, or extr — from…
Writes the motion prompt for a video clip — what moves, how the camera behaves, the physics and the audio, in the shape the chosen model wants.
Tests which individual taxa differ between groups on an amplicon ASV/feature table (phyloseq) using compositionally-aware methods - ALDEx2 (Dirichlet-MC CLR, conservative),…
Build, manage, and search spectral libraries for proteomics. Use when creating or working with spectral libraries for DIA analysis.
Meta-agent that routes bioinformatics requests to specialised sub-skills. Handles file type detection, analysis planning, report generation, and reproducibility export.
Guide to reproducing OmicVerse trajectory workflows spanning PAGA, Palantir, VIA, velocity coupling, and fate scoring notebooks. — from bg-szy/TOP-SKILLS
Master Rust async programming with Tokio, async traits, error handling, and concurrent patterns. Use when building async Rust applications, implementing concurrent system — from…
Point Cowork at your invoices and payments records -- builds an AR aging report, drafts escalating follow-up emails matched to each invoice's age and the client relationship, and…
Create production-ready Kubernetes manifests for Deployments, Services, ConfigMaps, and Secrets following best practices and security standards.
Enforce TypeScript strict mode and type safety. Use when setting up projects, reviewing code, or when type errors are ignored.
Query and download from NCBI Gene Expression Omnibus (GEO) and EMBL-EBI's BioStudies/ArrayExpress mirror.
Generate full songs and instrumental tracks with ElevenLabs Music on RunComfy via the `runcomfy` CLI.