Detect A/B compartments from Hi-C data using cooltools and eigenvector decomposition. Identify active (A) and inactive (B) chromatin compartments from contact matrices.
Search Open Targets drug-disease associations with natural language queries. Target validation powered by Valyu semantic search.
When the user wants to create, optimize, or audit integrations, plugins, or extensions pages. Also use when the user mentions "integrations page," "plugins," "extensions,"…
Final visual polish for an existing UI without redesigning it. Use after structure is clear, when asked to improve spacing, alignment, text hierarchy, readability, shadows,…
Cloud laboratory platform for automated protein testing and validation. Use when designing proteins and needing experimental validation including binding assays, expressi — from…
Analyzes spatial proteomics data from CODEX, IMC, and MIBI platforms including cell segmentation and protein colocalization.
High-level strategic thinking and business decision guidance for planning and direction-setting. Use when: making strategic decisions, evaluating business options, setting…
Assist Claude in running PyWGCNA through omicverse—preprocessing expression matrices, constructing co-expression modules, visualising eigengenes, and extracting hub genes — from…
Comprehensive guide for Dependency-Track - Software Composition Analysis (SCA) and SBOM management platform.
Stream-JSON chaining for multi-agent pipelines, data transformation, and sequential workflows — from bg-szy/TOP-SKILLS
Generate AI images with GPT-Image-2, FLUX, Gemini, Grok, Seedream, Reve and 50+ models via inference.sh CLI.
Comprehensive structural variant (SV) analysis skill for clinical genomics. Classifies SVs (deletions, duplications, inversions, translocations), assesses pathogenicity using…
When the user wants to add or optimize Open Graph metadata for social sharing. Also use when the user mentions "Open Graph," "og:tags," "og:title," "og:image," "og:description,"…
ISO 13485 Quality Management System specialist for medical device companies. Provides QMS implementation, maintenance, process optimization, and compliance expertise.
Create detailed implementation plans with granular tasks. Use before implementing features or complex changes.
Render videos from React/Remotion component code via inference.sh. Pass TSX code, get MP4. Supports all Remotion APIs: useCurrentFrame, useVideoConfig, spring, interpolat — from…
Fast miRNA quantification with isomiR detection and A-to-I editing analysis using miRge3. Use when quantifying known miRNAs quickly or analyzing isomiR variants and RNA e — from…
Patiently AI simplifies medical documents for patients. Takes doctor's letters, test results, prescriptions, discharge summaries, and clinical notes and explains them in clear,…
Orchestrates an end-to-end de novo genome assembly project, routing each step to the right genome-assembly skill rather than restating it.
Master systematic debugging techniques, profiling tools, and root cause analysis to efficiently track down bugs across any codebase or technology stack.
Differential binding analysis using DiffBind. Compare ChIP-seq peaks between conditions with statistical rigor. Requires replicate samples.
Master TypeScript's advanced type system including generics, conditional types, mapped types, template literals, and utility types for building type-safe applications.
Remove sequencing adapters from FASTQ files using Cutadapt and Trimmomatic. Supports single-end and paired-end reads, Illumina TruSeq, Nextera, and custom adapter sequenc — from…
Presentation toolkit (.pptx). Create/edit slides, layouts, content, speaker notes, comments, for programmatic presentation creation and modification. — from bg-szy/TOP-SKILLS
Write job posts that make the right person apply -- real role clarity, honest selling points, salary range handling, and requirements pruned to what actually predicts success.
When the user wants to run app install ads, user acquisition (UA), or promote mobile apps. Also use when the user mentions "app ads," "app install ads," "UA," "user acquisition,"…
Performs subgroup and heterogeneous treatment effect (HTE) analyses for clinical trials. Covers Mantel-Haenszel pooling, Breslow-Day, interaction tests in regression, RER — from…
Guide for creating high-quality MCP (Model Context Protocol) servers that enable LLMs to interact with external services through well-designed tools.
Measures geometric properties of protein structures with Biopython Bio.PDB - interatomic distances, distance matrices, bond and dihedral angles (phi/psi/chi, Ramachandran),…
Visualizes ChIP-seq data using deepTools (computeMatrix, plotHeatmap, plotProfile, bamCoverage, bamCompare), pyGenomeTracks (modern INI-driven track plots), Gviz (R…
Build production 1:1 stablecoin swaps with LI.FI Intents, where the amount sent equals the amount received with no visible gas or solver fees, on the same chain or across chains.
Route RunComfy music requests to ElevenLabs or ACE Step for vocal songs, instrumentals, multilingual tracks, audio inpainting, and outpainting, with documented prompts and…
Design homology-directed repair donor templates for CRISPR knock-ins using primer3-py. Create ssODN, dsDNA, or plasmid templates with optimized homology arms.
Marker gene-based taxonomic profiling using MetaPhlAn 4. Provides accurate species-level relative abundances using clade-specific markers.
Collaborative design exploration that refines ideas into validated specs through iterative questioning.
PyTorch-native graph neural networks for molecules and proteins. Use when building custom GNN architectures for drug discovery, protein modeling, or knowledge graph reaso — from…
Reconstruct ancestral states at internal phylogenetic nodes for sequences (PAML codeml, IQ-TREE --ancestral, GRASP, FastML), discrete traits (corHMM hidden-rate Markov, ape::ace,…
Comprehensive spreadsheet creation, editing, and analysis with support for formulas, formatting, data analysis, and visualization.
NEAR AI Cloud private inference and verification. Use when integrating NEAR AI Cloud API for verifiable private AI inference, verifying model or gateway TEE attestation ( — from…
Build Manhattan, Miami, QQ, and locuszoom-style regional plots from GWAS, TWAS, PWAS, and QTL summary statistics with correct genomic-inflation diagnostics, multi-trait overlays,…
Perform comprehensive code reviews covering security, style, performance, and best practices. Use when reviewing code changes before commit or merge, auditing existing code, or…
Use when preparing photos or images for a news wire, publication, photo CMS, or archive — embedding caption, byline, credit, alt text, keywords, copyright or Creative Commons…
Parse FCS (Flow Cytometry Standard) files v2.0-3.1. Extract events as NumPy arrays, read metadata/channels, convert to CSV/DataFrame, for flow cytometry data preprocessin — from…
Build an insurance-grade home inventory from a folder of photos and receipts -- identifies items, pulls values from receipts, estimates replacement costs, organizes by room, and…
This is the required documentation for agents operating on the CloudBase Relational Database through MCP.
Use when the user asks for Customer Onboarding Course from supplied source materials. Trigger language: customer onboarding; client onboarding; onboarding training; implementation…
Score and prioritize neoantigens and epitopes for immunogenicity using multi-factor models combining MHC binding, processing, expression, and sequence features.
Build slide decks and presentations for research talks. Use this for making PowerPoint slides, conference presentations, seminar talks, research presentations, thesis def — from…
Detect signatures of natural selection using Fst, Tajima's D, iHS, XP-EHH, and other selection statistics.
WordPress performance optimization - Core Web Vitals, image/video compression, caching, asset optimization, and speed testing.
Tests associations between categorical variables in clinical data using chi-square, Fisher's exact, Boschloo, Cochran-Mantel-Haenszel, and modern McNemar variants with calibrated…
Analyzes cfDNA fragment size distributions and fragmentomics features using FinaleToolkit or Griffin.
Predict restriction digest fragment sizes and gel patterns using Biopython Bio.Restriction. Computes fragment lengths and sequences for single and double digests on linear or…
Judges whether a macromolecular model (or a region of it) is reliable enough to build on, using resolution, R-free, B-factors, MolProbity geometry, and predicted-model confidence…
Toolkit for styling artifacts with a theme. These artifacts can be slides, docs, reportings, HTML landing pages, etc.
AgentLink gives an AI agent a verified, human-backed on-chain identity. Use it to link and register an agent wallet with a biomapped human owner in BiomapperAgentRegistry — from…
When the user wants to add, optimize, or audit breadcrumb navigation. Also use when the user mentions "breadcrumbs," "breadcrumb trail," "breadcrumb nav," "breadcrumb links,"…
When the user wants to choose an SEO-friendly domain for a new site—brand vs keyword domain, TLD selection, or domain best practices.
Render videos from React/Remotion component code via inference.sh. Pass TSX code, get MP4. Supports all Remotion APIs: useCurrentFrame, useVideoConfig, spring, interpolat — from…
Presentation creation, editing, and analysis. When Claude needs to work with presentations (.pptx files) for: (1) Creating new presentations, (2) Modifying or editing con — from…