Calculate alignment statistics including sequence identity, conservation scores, substitution matrices, and similarity metrics.
Computes sample size and power for clinical trials including continuous, binary, and time-to-event endpoints; superiority, non-inferiority, and equivalence designs; FDA 2 — from…
End-to-end post-GWAS causal inference pipeline orchestrating heritability partitioning, genetic correlation, Mendelian randomization with CHP-aware sensitivity (CAUSE / L — from…
You MUST use this before any creative work - creating features, building components, adding functionality, or modifying behavior.
Use when completing tasks, implementing major features, or before merging to verify work meets requirements — from bg-szy/TOP-SKILLS
When agent sessions generate millions of tokens of conversation history, compression becomes mandatory.
Create, revise, polish, inspect, export, and preview complete stylized Roblox R6 and R15 character animations on authentic Studio-derived Blender rigs through MCP.
Modify protein structures using Biopython Bio.PDB. Use when transforming coordinates, removing atoms or residues, adding new entities, modifying B-factors and occupancies — from…
Corrects fluorophore spillover (conventional compensation) or spectral overlap (spectral unmixing) and applies variance-stabilizing transforms (logicle/biexponential, arcsinh,…
When the user wants to create, optimize, or audit FAQ page content. Also use when the user mentions "FAQ page," "frequently asked questions," "help page," "Q&A page," "FAQ…
Point Cowork at a folder of resumes plus a job description -- screens every candidate against the actual requirements, produces a ranked shortlist with evidence, drafts…
Read, write, and create single-cell data objects using Seurat (R) and Scanpy (Python). Use for loading 10X Genomics data, importing/exporting h5ad and RDS files, creating — from…
ATAC-seq library quality control -- TSS enrichment, FRiP, fragment-size periodicity, library complexity (NRF/PBC1/PBC2), mitochondrial fraction, and ENCODE 4 thresholds.
Toolkit for styling artifacts with a theme. These artifacts can be slides, docs, reportings, HTML landing pages, etc.
Single-cell ATAC-seq analysis with Signac (R/Seurat) and ArchR. Process 10X Genomics scATAC data, perform QC, dimensionality reduction, clustering, peak calling, and moti — from…
View, convert, and understand SAM/BAM/CRAM alignment files using samtools and pysam. Use when inspecting alignments, converting between formats, or understanding alignmen — from…
Optimize AgentDB performance with quantization (4-32x memory reduction), HNSW indexing (150x faster search), caching, and batch operations.
Assigns pathogen lineages (SARS-CoV-2 Pangolin via UShER mode; Nextclade clade + QC; pango-designation alias_key.json resolution) and tracks variant frequencies over time using…
Maps between gene identifier systems (Ensembl, Entrez, HGNC symbol, UniProt, RefSeq, MANE) using AnnotationDbi, biomaRt, mygene, pyensembl, and Ensembl REST.
Identify differentially bound regions across CLIP-seq conditions (knockdown vs control, treatment vs vehicle, disease vs healthy) using DEWSeq (sliding-window DESeq2), Flipper…
Create structured docs from scratch — PRDs, technical specs, design docs, decision records, knowledge bases.
Document toolkit (.docx). Create/edit documents, tracked changes, comments, formatting preservation, text extraction, for professional document processing. — from bg-szy/TOP-SKILLS
Comprehensive Excel spreadsheet creation, editing, and analysis with support for formulas, formatting, charts, data analysis, and visualization.
Assesses RNA-seq data quality specifically for alternative splicing analysis. QC layers include experimental design audit (library prep, read length, depth, replicates), STAR…
Convert files and office documents to Markdown. Supports PDF, DOCX, PPTX, XLSX, images (with OCR), audio (with transcription), HTML, CSV, JSON, XML, ZIP, YouTube URLs, EP — from…
Render videos from React/Remotion component code via inference.sh. Pass TSX code, get MP4. Supports all Remotion APIs: useCurrentFrame, useVideoConfig, spring, interpolat — from…
Generate text-to-video with Wan 2.7 (Wan-AI's flagship motion model) on RunComfy. Documents Wan 2.7's strengths (multi-reference conditioning, audio-driven lip-sync via ` — from…
Cell type assignment from marker expression in IMC data. Covers manual gating, clustering, and automated classification approaches.
Write job posts that make the right person apply -- real role clarity, honest selling points, salary range handling, and requirements pruned to what actually predicts success.
Install a complete design-token theme into any project in one pass -- pulls a style from the Open Agent Stack design-styles collection (aurora-mesh, cirrus, liquid-glass,…
Statistical testing for differentially abundant proteins between conditions. Covers preprocessing (log2 transformation, normalization), limma and DEqMS workflows with emp — from…
Visualize differential expression results using DESeq2/edgeR built-in functions. Covers plotMA, plotDispEsts, plotCounts, plotBCV, sample distance heatmaps, and p-value…
Extracts and analyzes competitors' ads from ad libraries (Facebook, LinkedIn, etc.) to understand what messaging, problems, and creative approaches are working.
Apply behavioral science and mental models to marketing decisions, prioritized using a psychological leverage and feasibility scoring system. — from bg-szy/TOP-SKILLS
End-to-end genome annotation pipeline from assembled contigs to functional annotation, covering repeat masking, gene prediction, and functional assignment for both prokaryotic and…
Quality control for long-read sequencing data using NanoPlot, NanoStat, and chopper. Generate QC reports, filter reads by length and quality, and visualize read character — from…
Create AI avatar and talking head videos via inference.sh CLI. Recommended: P-Video-Avatar (fastest, cheapest, built-in TTS). Also: OmniHuman, Fabric, PixVerse.
Generate consensus sequences and manage reference files using samtools. Use when creating consensus from alignments, indexing references, or creating sequence dictionarie — from…
Use when design is complete and you need detailed implementation tasks for engineers with zero codebase context - creates comprehensive implementation plans with exact fi — from…
When the user wants to create X (Twitter) post copy, threads, or optimize for X platform. Also use when the user mentions "X post," "X thread," "Twitter post," "Twitter t — from…
Huawei Cloud ModelArts platform integration. Modular design, OBS as primary storage support, environment variable authentication, includes pool plugin management and node — from…
Generate AI images with FLUX, Gemini, Grok, Seedream, Reve and 50+ models via inference.sh CLI. Models: FLUX Dev LoRA, FLUX.2 Klein LoRA, Gemini 3 Pro Image, Grok Imagine — from…
Use when the user asks for Community Onboarding from supplied source materials. Trigger language: community onboarding; member onboarding; paid community start here.
Lip-sync a face to a specific audio track on RunComfy via the `runcomfy` CLI. Routes across ByteDance OmniHuman (audio-driven full-body avatar from a portrait + audio), S — from…
End-to-end clinical trial analysis workflow from CDISC SDTM/ADaM loading through ICH E9(R1) estimand-driven primary analysis to CONSORT 2025 regulatory-compliant reporting.
Score and prioritize neoantigens and epitopes for immunogenicity using multi-factor models combining MHC binding, processing, expression, and sequence features.
Intelligently organizes files and folders by understanding context, finding duplicates, and suggesting better organizational structures.
High-performance toolkit for genomic interval analysis in Rust with Python bindings. Use when working with genomic regions, BED files, coverage tracks, overlap detection — from…
Use when encountering any bug, test failure, or unexpected behavior, before proposing fixes — from bg-szy/TOP-SKILLS
Enforces local testing before any deployment. MUST be used before running vercel, git push, or any deployment command. Prevents deploying untested code.
Use when implementation is complete, all tests pass, and you need to decide how to integrate the work - guides completion of development work by presenting structured opt — from…
Process and analyze tissue images from spatial transcriptomics data using Squidpy. Extract image features, segment cells/nuclei, and compute morphological features from H — from…
Detects m6A modifications from Oxford Nanopore direct-RNA-sequencing (ONT DRS) signal data using m6Anet (Hendra 2022 *Nat Methods* 19:1590; multiple-instance-learning neural…
Execute autonomous multi-step research using Google Gemini Deep Research Agent. Use for: market analysis, competitive landscaping, literature reviews, technical research — from…
Load and preprocess imaging mass cytometry (IMC) and MIBI data. Covers MCD/TIFF handling, hot pixel removal, and image normalization.
Analyzes differential transcript usage (DTU) and isoform switches with functional consequence prediction (NMD via 50nt rule, ORF disruption, protein domain loss/gain, signal…
Connect GenLayer Intelligent Contract decisions to ERC-7710-style delegated authority. Use when an agent needs to design the interface, message schema, relayer/bridge pat — from…
When the user wants to create, optimize, or structure a changelog or release notes page. Also use when the user mentions "changelog," "release notes," "what's new," "updates,"…
Deploy applications and websites to Vercel instantly. Use when asked to \"Deploy my app\", \"Deploy this to production\", \"Create a preview deployment\", or \"Push this live\".
Build automated billing systems for recurring payments, invoicing, subscription lifecycle, and dunning management.