Use when preparing the narrative, sources, and design context for a new editable PPTX deck.
Design AI-first interfaces that build ongoing relationships through memory, trust evolution, and collaborative planning.
Prepare for US medical licensing exams with progress tracking, weak area analysis, question bank management, and residency match planning.
When the user wants to create, optimize, or structure a status page. Also use when the user mentions "status page," "status.yourdomain.com," "uptime," "service health," "incident…
Browser automation for AI agents via inference.sh. Navigate web pages, interact with elements using @e refs, take screenshots, record video.
Statistical methods for calling hits in CRISPR screens. Covers MAGeCK, BAGEL2, drugZ, and custom approaches for identifying essential and resistance genes.
Perform V(D)J alignment and clonotype assembly from TCR-seq or BCR-seq data using MiXCR. Use when processing raw immune repertoire sequencing data to identify clonotypes — from…
Parse and analyze multiple sequence alignments using Biopython. Extract sequences, identify conserved regions, analyze gaps, work with annotations, and manipulate alignme — from…
Audit and sync design tokens between the source of truth (tokens.json, Figma variables export) and the code that should consume them (Tailwind config, CSS custom properties, theme…
Calculate alignment statistics including sequence identity, conservation scores, substitution matrices, and similarity metrics.
Builds and simulates multi-species metabolic community models from member genome-scale models, using MICOM for abundance-weighted steady-state community FBA and cooperative…
Project scaffolding templates for new applications. Use when creating new projects from scratch. Contains 12 templates for various tech stacks. — from bg-szy/TOP-SKILLS
Use when facing 2+ independent tasks that can be worked on without shared state or sequential dependencies — from bg-szy/TOP-SKILLS
Extract, process, and deduplicate reads using Unique Molecular Identifiers (UMIs) with umi_tools. Use when library prep includes UMIs and accurate molecule counting is ne — from…
Evaluate systems through an entropy/negentropy lens — is this system decaying or growing? Use when making architecture decisions, evaluating system health, or when the user…
Best practices for writing, reviewing, and refactoring React Flow / @xyflow/react v12 canvases. Use when work touches React Flow components, custom nodes, custom edges, handles,…
MUST be used for Vue.js tasks. Strongly recommends Composition API with `<script setup>` and TypeScript as the standard approach. Covers Vue 3, SSR, Volar, vue-tsc.
Joint genotype calling across multiple samples using GATK CombineGVCFs and GenotypeGVCFs. Essential for cohort studies, population genetics, and leveraging VQSR.
Assesses Oxford Nanopore and PacBio long-read quality with NanoPlot, cramino, NanoComp, pycoQC/toulligQC, and seqkit, and filters reads with chopper/Filtlong for the downstream…
Review frontend code for accessibility, UI security, missing states, and UX regressions. Use when asked to review React components, run a pre-merge frontend review, or check a11y…
Implement Linkerd service mesh patterns for lightweight, security-focused service mesh deployments. Use when setting up Linkerd, configuring traffic policies, or implemen — from…
Generate AI videos on RunComfy via the `runcomfy` CLI — a smart router across the full video-model catalog: HappyHorse 1.0 (Arena #1, native in-pass audio), Wan-AI Wan 2- — from…
Toolkit for styling artifacts with a theme. These artifacts can be slides, docs, reportings, HTML landing pages, etc.
Protein grouping and inference from peptide identifications. Use when resolving protein ambiguity from shared peptides.
Simulate transcription factor perturbation effects on cell state in silico with CellOracle and Dynamo, and predict transcriptional responses to genetic perturbations with GEARS,…
Create portable bioinformatics pipelines with Workflow Description Language (WDL) using Cromwell or miniwdl execution engines.
Master end-to-end testing with Playwright and Cypress to build reliable test suites that catch bugs, improve confidence, and enable fast deployment.
Two services in one skill: (1) Web3 on-chain data via Chainbase CLI — use when the user asks about blockchain data, token holders, wallet addresses, token prices, ENS dom — from…
Guide users through a structured workflow for co-authoring documentation. Use when user wants to write documentation, proposals, technical specs, decision docs, or simila — from…
Amplicon sequence variant (ASV) inference from 16S rRNA or ITS amplicon sequencing using DADA2. Covers quality filtering, error learning, denoising, and chimera removal — from…
Detects circadian and ultradian rhythms in time-series omics data using CosinorPy cosinor models, MetaCycle (JTK_CYCLE, ARSER), and RAIN non-parametric tests.
Single-cell ATAC-seq analysis with Signac (R/Seurat) and ArchR. Process 10X Genomics scATAC data, perform QC, dimensionality reduction, clustering, peak calling, and moti — from…
Create SEO-optimized marketing content with consistent brand voice. Includes brand voice analyzer, SEO optimizer, content frameworks, and social media templates.
End-to-end pooled and single-cell CRISPR screen analysis from FASTQ to hit genes. Orchestrates library design QC, guide counting, six-stage screen QC (plasmid Gini, replicate…
Advanced GitHub Actions workflow automation with AI swarm coordination, intelligent CI/CD pipelines, and comprehensive repository management — from bg-szy/TOP-SKILLS
Guide for creating MCP (Model Context Protocol) servers. Use this when building integrations with external services, creating new MCP servers, or connecting Claude to APIs.
Annotate copy number variant segments with overlapping genes, dosage-sensitivity scores, cancer driver databases, population frequencies, and clinical-variant content.
Per-CpG differential methylation testing from bisulfite sequencing count data or beta-value matrices.
Profile and optimize Python code using cProfile, memory profilers, and performance best practices. Use when debugging slow Python code, optimizing bottlenecks, or improvi — from…
Automate Twitter/X with posting, engagement, and user management via inference.sh CLI. Apps: x/post-tweet, x/post-create (with media), x/post-like, x/post-retweet, x/dm-s — from…
Film and video storyboarding with shot vocabulary, continuity rules, and panel layout. Covers shot types, camera angles, movement, 180-degree rule, and annotation format — from…
Analyzes chemical libraries by scaffold using Bemis-Murcko scaffolds, generic frameworks, cyclic skeletons, matched molecular pair (MMP) analysis via mmpdb, R-group decomposition,…
Structured competitive analysis with feature matrices, SWOT, positioning maps, and UX review. Covers research frameworks, pricing comparison, review mining, and visual de — from…
Applies Anthropic's official brand colors and typography to any sort of artifact that may benefit from having Anthropic's look-and-feel.
Generate, inpaint, and outpaint music with ACE Step on RunComfy via the `runcomfy` CLI. ACE Step is StepFun-AI's open-weights music foundation model — tag-driven composit — from…
Quality control for long-read sequencing data using NanoPlot, NanoStat, and chopper. Generate QC reports, filter reads by length and quality, and visualize read character — from…
MS-DIAL-based metabolomics preprocessing as alternative to XCMS. Covers peak detection, alignment, annotation, and export for downstream analysis.
Comprehensive backend development guide for Node.js/Express/TypeScript microservices. Use when creating routes, controllers, services, repositories, middleware, or workin — from…
Pythonic wrapper around RDKit with simplified interface and sensible defaults. Preferred for standard drug discovery including SMILES parsing, standardization, descriptor — from…
Use when Codex, Hermes, OpenClaw, Claude Code, Cowork, or another AI agent needs to plan, review, implement, audit, or improve email work focused on responsive email desi — from…
Build a quarterly business review from a client folder -- reports, usage exports, support tickets, meeting notes, emails.
Senior QMS Audit Expert for internal and external quality management system auditing. Provides ISO 13485 audit expertise, audit program management, nonconformity identifi — from…
Writes the motion prompt for a video clip — what moves, how the camera behaves, the physics and the audio, in the shape the chosen model wants.
Manage Supabase projects, databases, migrations, Edge Functions, and storage using the `supabase` CLI.
Use when the user asks for Sales Enablement Training from supplied source materials. Trigger language: sales enablement training; sales readiness; go-to-market training; product…
Detect transcription factor binding sites through footprinting analysis in ATAC-seq data using TOBIAS.
Evaluates genome assembly quality across the three orthogonal axes - contiguity (QUAST auN/NG50/NGx, not bare N50), completeness (BUSCO/compleasm gene-space plus Merqury k-mer…
Comprehensive chemical safety and toxicology assessment integrating ADMET-AI predictions, CTD toxicogenomics, FDA label safety data, DrugBank safety profiles, and STITCH…
Improves the quality of images, especially screenshots, by enhancing resolution, sharpness, and clarity.
Use when the user asks for Report Briefing from supplied source materials. Trigger language: report briefing; research presentation; whitepaper summary; benchmark report;…