Work with FASTQ quality scores using Biopython. Use when analyzing read quality, filtering by quality, trimming low-quality bases, or generating quality reports.
Use when starting feature work that needs isolation from current workspace or before executing implementation plans - creates isolated git worktrees with smart directory — from…
Root cause analysis for debugging. Use when bugs, test failures, or unexpected behavior have non-obvious causes, or after multiple fix attempts have failed.
Write effective blameless postmortems with root cause analysis, timelines, and action items. Use when conducting incident reviews, writing postmortem documents, or improving…
Enumerates virtual chemical libraries via reaction SMARTS transformations using RDKit and Reaction templates, with explicit handling of atom mapping, template extraction (RDKit…
Create new skills, modify and improve existing skills, and measure skill performance. Use when users want to create a skill from scratch, edit, or optimize an existing sk — from…
Analyzes your recent Claude Code chat history to identify coding patterns, development gaps, and areas for improvement, curates relevant learning resources from HackerNew — from…
Run 250+ AI apps via inference.sh CLI - image generation, video creation, LLMs, search, 3D, Twitter automation.
Support for sending an email with a link the recipient can click to prove they own the email address.
Render videos from React/Remotion component code via inference.sh. Pass TSX code, get MP4. Supports all Remotion APIs: useCurrentFrame, useVideoConfig, spring, interpolat — from…
Detect and remove doublets (multiple cells captured in one droplet) from single-cell RNA-seq data. Uses Scrublet (Python), DoubletFinder (R), and scDblFinder (R).
Internal shared-reference support package for installed nature-writing, nature-polishing, nature-reader, and nature-paper2ppt skills.
Predict TCR-epitope specificity using ERGO-II and deep learning models for T-cell receptor antigen recognition.
Use when Codex, Hermes, OpenClaw, Claude Code, Cowork, or another AI agent needs to plan, review, implement, audit, or improve email work focused on behavioral triggers — from…
Generate genome browser visualizations using pyGenomeTracks or IGV batch scripting for publication figures.
When the user wants to create, optimize, or audit FAQ page content. Also use when the user mentions "FAQ page," "frequently asked questions," "help page," "Q&A page," "FAQ…
Build reproducible scientific documents, presentations, and websites with Quarto supporting R, Python, Julia, and Observable JS.
Quick-start guide and API overview for the OpenServ Ideaboard - a platform where AI agents can submit ideas, pick up work, collaborate with multiple agents, and deliver x — from…
Use when implementation is complete, all tests pass, and you need to decide how to integrate the work - guides completion of development work by presenting structured opt — from…
Standard single-cell RNA-seq analysis pipeline. Use for QC, normalization, dimensionality reduction (PCA/UMAP/t-SNE), clustering, differential expression, and visualizati — from…
Generate alignment statistics using samtools flagstat, stats, depth, coverage, and mosdepth. Use when assessing alignment quality, calculating coverage, or generating QC reports.
Manage and troubleshoot PATH configuration in zsh. Use when adding tools to PATH (bun, nvm, Python venv, cargo, go), diagnosing "command not found" errors, validating PATH…
Search PubMed for scientific literature. Use when the user asks to find papers, search literature, look up research, find publications, or asks about recent studies.
Build volcano and MA plots from differential-expression / association results with LFC shrinkage, FDR-adjusted thresholds, sensible label placement, and axis-truncation…
Generate AI videos with Google Veo, Seedance, Wan, Grok and 40+ models via inference.sh CLI. Models: Veo 3.1, Veo 3, Seedance 1.5 Pro, Wan 2.5, Grok Imagine Video, OmniHu — from…
Use when facing 3+ independent failures that can be investigated without shared state or dependencies.
Use when Codex, Hermes, OpenClaw, Claude Code, Cowork, or another AI agent needs to plan, review, implement, audit, or improve email work focused on time-based nurture st — from…
Guide Claude through ingesting TCGA sample sheets, expression archives, and clinical carts into omicverse, initialising survival metadata, and exporting annotated AnnData files.
Use when the user asks for Sales Onboarding from supplied source materials. Trigger language: sales onboarding; sales onboarding program; new sales rep ramp.
Align preprocessed CLIP-seq reads (eCLIP, iCLIP, iCLIP2, PAR-CLIP) to genome with STAR or bowtie2 using crosslink-preserving parameters, choosing between unique-mapper-only and…
Comprehensive backend development guide for Supabase Edge Functions + PostgreSQL. Use when working with Supabase (database, auth, storage, realtime), Edge Functions, PostgreSQL,…
Comprehensive SecOps skill for application security, vulnerability management, compliance, and secure development practices.
Targeted metabolomics analysis using MRM/SRM with standard curves. Covers absolute quantification, method validation, and quality assessment.
Manage breaking API changes, migration guides, deprecation notices, and semver versioning. Use when introducing breaking changes, writing migration paths, updating changelogs, or…
Modify protein structures using Biopython Bio.PDB. Use when transforming coordinates, removing atoms or residues, adding new entities, modifying B-factors and occupancies — from…
Convert Stitch HTML designs into React Native screens using native primitives, StyleSheet rules, and mobile platform checks.
Run 250+ AI apps via inference.sh CLI - image generation, video creation, LLMs, search, 3D, Twitter automation.
Performs probe filtering and sample-level QC on Illumina Infinium methylation arrays (450K / EPIC / EPICv2) to decide which probes and samples to trust.
When the user wants to create, optimize, or audit alternatives or comparison content (page or blog article).
Multi-agent workflow examples to work together on the OpenServ Platform. Covers agent discovery, multi-agent workspaces, task dependencies, and workflow orchestration usi — from…
Download large datasets from NCBI efficiently using EPost, history server, batching, rate limiting, and retry logic.
Use when starting feature work that needs isolation from current workspace or before executing implementation plans - creates isolated git worktrees with smart directory — from…
Verify that browser profiles are actually isolated from one another instead of assuming it - confirm each profile's timezone agrees with its own exit IP, that WebRTC exposes only…
PLINK file formats, format conversion, and quality control filtering for population genetics. Convert between VCF, BED/BIM/FAM, and PED/MAP formats, apply MAF, genotyping — from…
QIIME2 command-line workflow for 16S/ITS amplicon analysis. Alternative to DADA2/phyloseq R workflow with built-in provenance tracking.
Use omicverse's pyComBat wrapper to remove batch effects from merged bulk RNA-seq or microarray cohorts, export corrected matrices, and benchmark pre/post correction visu — from…
Create generative art using p5.js with seeded randomness. Use this when creating procedural art, interactive visualizations, or algorithmic designs.
Use when facing 2+ independent tasks that can be worked on without shared state or sequential dependencies — from bg-szy/TOP-SKILLS
Compare Hi-C contact matrices between conditions to identify differential chromatin interactions. Compute log2 fold changes, statistical significance, and visualize diffe — from…
Checkpoint framework and validation rules for all agents. Ensures quality gates are passed at every stage of development.
Create reproducible bioinformatics analysis reports with R Markdown including code, results, and visualizations in HTML, PDF, or Word format.
Clean Architecture and SOLID principles guide. Use this when designing systems, reviewing architecture, or making structural decisions.
Draw and export phylogenetic trees using Biopython Bio.Phylo with matplotlib and modern alternatives.
When the user wants to add, optimize, or audit popups or modals for lead capture or offers. Also use when the user mentions "popup," "modal," "lightbox," "overlay," "exit-intent,"…
Detect single-nucleotide crosslink (CL) sites in CLIP-seq data using truncation patterns (iCLIP/eCLIP CITS), crosslink-induced mutations (HITS-CLIP CIMS deletions, PAR-CLIP…
Specialized lipidomics analysis for lipid identification, quantification, and pathway interpretation.
Conduct enterprise-grade research with multi-source synthesis, citation tracking, and verification. Use when user needs comprehensive analysis requiring 10+ sources, veri — from…
KEGG pathway and module enrichment analysis using clusterProfiler enrichKEGG and enrichMKEGG. Use when identifying metabolic and signaling pathways over-represented in a — from…
Implements missing-data sensitivity analyses for confirmatory clinical trials including MMRM under MAR (with Kenward-Roger correction), reference-based multiple imputation (J2R,…
Documentation generation workflow covering API docs, architecture docs, README files, code comments, and technical writing. — from bg-szy/TOP-SKILLS