Production-ready single-cell and expression matrix analysis using scanpy, anndata, and scipy. Performs scRNA-seq QC, normalization, PCA, UMAP, Leiden/Louvain clustering,…
Patiently AI simplifies medical documents for patients. Takes doctor's letters, test results, prescriptions, discharge summaries, and clinical notes and explains them in clear,…
Comprehensive frontend development skill for building modern, performant web applications using ReactJS, NextJS, TypeScript, Tailwind CSS.
Video ad creation with exact platform-specific specs for TikTok, Instagram, YouTube, Facebook, LinkedIn.
Generate and edit images with OpenAI GPT Image 2 (ChatGPT Images 2.0) on RunComfy. Documents GPT Image 2's strengths (embedded text, logos, multilingual typography, instr — from…
Browser automation for AI agents via inference.sh. Navigate web pages, interact with elements using @e refs, take screenshots, record video.
Run defensive pre-release security tests for Python web applications. Use for FastAPI, Django, Flask, and ASGI services: the common interface between Python web apps and servers.
Applies ACMG/AMP 2015 framework with ClinGen SVI specifications, Tavtigian 2018/2020 Bayesian point system, Abou Tayoun 2018 PVS1 decision tree, Pejaver 2022 calibrated PP3/BP4…
Detect syntenic blocks and structural rearrangements between genomes using MCScanX (Wang 2012), JCVI/MCScan (Tang 2008 Python), GENESPACE (Lovell 2022) for orthology-anch — from…
Generate images with Google Nano Banana 2 (Gemini-family flash-tier text-to-image) on RunComfy — bundled with the model's documented prompting patterns so the skill gets — from…
Create SEO-optimized marketing content with consistent brand voice. Includes brand voice analyzer, SEO optimizer, content frameworks, and social media templates.
Migrate from AngularJS to Angular using hybrid mode, incremental component rewriting, and dependency injection updates.
Build automated AI workflows combining multiple models and services. Patterns: batch processing, scheduled tasks, event-driven pipelines, agent loops.
Technical leadership guidance for engineering teams, architecture decisions, and technology strategy.
Use when executing implementation plans with independent tasks in the current session — from bg-szy/TOP-SKILLS
Use when Codex, Hermes, OpenClaw, Claude Code, Cowork, or another AI agent needs to plan, review, implement, audit, or improve email work focused on responsive email desi — from…
Profile functional potential of metagenomes using HUMAnN3 and similar tools. Use when obtaining pathway abundances, gene family counts, or functional annotations from met — from…
Calculates tumor mutational burden from WES/WGS/panel data with Friends of Cancer Research harmonization equations, per-assay calibration (FDA 10/Mb = 7.8 TSO500 = 8.4…
Checks whether a PCR primer PAIR amplifies only the intended target genome-wide, using pair-aware in-silico PCR (MFEprimer-3.0, UCSC isPcr, NCBI Primer-BLAST) plus a primer3-py…
Production-ready VCF processing, variant annotation, mutation analysis, and structural variant (SV/CNV) interpretation for bioinformatics questions.
Handles batch effects in bulk RNA-seq via design-matrix inclusion (the correct path for DE), ComBat/ComBat-seq for visualization, SVA for unknown latent factors, RUVSeq for…
Implement Kubernetes security policies including NetworkPolicy, PodSecurityPolicy, and RBAC for production-grade security.
Generates standardized quality control reports by aggregating metrics from FastQC, alignment, and other tools using MultiQC.
Therapeutics Data Commons. AI-ready drug discovery datasets (ADME, toxicity, DTI), benchmarks, scaffold splits, molecular oracles, for therapeutic ML and pharmacological — from…
Use when receiving code review feedback, before implementing suggestions, especially if feedback seems unclear or technically questionable - requires technical rigor and — from…
Deep learning-based variant calling from long reads using Clair3 for SNPs and small indels. Use when calling germline variants from ONT or PacBio alignments, particularly — from…
Implement Stripe payment processing for robust, PCI-compliant payment flows including checkout, subscriptions, and webhooks.
Applies Anthropic's official brand colors and typography to any sort of artifact that may benefit from having Anthropic's look-and-feel.
Targeted metabolomics analysis using MRM/SRM with standard curves. Covers absolute quantification, method validation, and quality assessment.
Supervised and unsupervised multi-omics integration with mixOmics. Includes sPLS for pairwise integration and DIABLO for multi-block discriminant analysis.
Call topologically associating domains (TADs) from Hi-C data using insulation score, HiCExplorer, and other methods.
Use when a HyperFrames composition needs seek-safe 2D/3D keyframes, GSAP timelines, CSS keyframes, Anime.js, WAAPI, FLIP, paths, masks, SVG morph/draw, text trails, 3D depth, or…
Film and video storyboarding with shot vocabulary, continuity rules, and panel layout. Covers shot types, camera angles, movement, 180-degree rule, and annotation format — from…
Firecrawl handles all web operations with superior accuracy, speed, and LLM-optimized output. Replaces all built-in and third-party web, browsing, scraping, research, new — from…
Git branching strategy expertise with flow-aware automation. Auto-invokes when branching strategies (gitflow, github flow, trunk-based), branch creation, branch naming, merging…
Performs subgroup and heterogeneous treatment effect (HTE) analyses for clinical trials. Covers Mantel-Haenszel pooling, Breslow-Day, interaction tests in regression, RER — from…
Use when Codex, Hermes, OpenClaw, Claude Code, Cowork, or another AI agent needs to plan, review, implement, audit, or improve email work focused on repo-aware email impl — from…
Supervised and unsupervised multi-omics integration with mixOmics. Includes sPLS for pairwise integration and DIABLO for multi-block discriminant analysis.
Orchestrates an end-to-end CRISPR editing experiment design from target gene to delivery-ready, validatable constructs.
Comprehensive DevOps skill for CI/CD, infrastructure automation, containerization, and cloud platforms (AWS, GCP, Azure).
Load spatial transcriptomics data from Visium, Xenium, MERFISH, Slide-seq, and other platforms using Squidpy and SpatialData.
Shell history management with Atuin. Use when configuring shell history, setting up history sync, searching command history, importing history from other shells, troubleshooting…
Reconcile a recorded home-bar inventory against supplied physical bottle observations. Use after purchases, use, moves, or a long gap when every record and observation needs one…
Find bugs, security vulnerabilities, and code quality issues in local branch changes. Use when asked to review changes, find bugs, security review, or audit code on the c — from…
Design short-term, long-term, and graph-based memory architectures. Use when building agents that must persist across sessions, needing to maintain entity consistency acr — from…
When the user wants to design, optimize, or audit masonry (Pinterest-style) layouts for content display.
Generic compatibility guide for Sequenzy operations. Use for broad Sequenzy references, but prefer sequenzy-email-marketing for campaigns and campaign lifecycle control (cancel,…
Guide users through a structured workflow for co-authoring documentation. Use when user wants to write documentation, proposals, technical specs, decision docs, or simila — from…
Guide for implementing obsidian.nvim - a Neovim plugin for Obsidian vault management. Use when configuring, troubleshooting, or extending obsidian.nvim features including…
Implement GDPR-compliant data handling with consent management, data subject rights, and privacy by design.
Searches for non-coding RNA homologs and classifies RNA families using Infernal covariance model searches against the Rfam database.
飞书视频会议：让机器人代当前用户加入/离开正在进行的会议，并读取会议期间的实时事件（参会人加入与离开、发言、聊天、屏幕共享等）。1. 用户提供 9 位会议号、要求代为入会或离会时使用 +meeting-join / +meeting-leave——会真实产生入会/离会记录。2.
Call SNPs and indels from aligned reads using bcftools mpileup and call. Use when detecting variants from BAM files or generating VCF from alignments. — from bg-szy/TOP-SKILLS
Infer gene regulatory networks from bulk or general expression data with mutual-information (ARACNe) and tree-ensemble (GENIE3, GRNBoost2) methods, and infer transcription-factor…
Extract and analyze data from invoices, receipts, bank statements, and financial documents. Categorize expenses, track recurring charges, and generate expense reports.
Golang performance optimization patterns and methodology - if X bottleneck, then apply Y. Covers allocation reduction, CPU efficiency, memory layout, GC tuning, pooling — from…
Generate reverse complements and complements of DNA/RNA sequences using Biopython. Use when working with opposite strands, primer design, or converting between template a — from…
Automate Twitter/X with posting, engagement, and user management via inference.sh CLI. Apps: x/post-tweet, x/post-create (with media), x/post-like, x/post-retweet, x/dm-s — from…
Use omicverse's pyComBat wrapper to remove batch effects from merged bulk RNA-seq or microarray cohorts, export corrected matrices, and benchmark pre/post correction visu — from…
Validates docked / generated protein-ligand poses using PoseBusters physical-validity tests, strain energy quantification, geometric checks (planarity, vdW overlap, bond/angle…