Sort alignment files by coordinate or read name using samtools and pysam. Use when preparing BAM files for indexing, variant calling, or paired-end analysis.
Optimize Apache Spark jobs with partitioning, caching, shuffle optimization, and memory tuning. Use when improving Spark performance, debugging slow jobs, or scaling data — from…
Predict restriction digest fragment sizes and gel patterns using Biopython Bio.Restriction. Computes fragment lengths and sequences for single and double digests on linear or…
Generate full songs and instrumental tracks with ElevenLabs Music on RunComfy via the `runcomfy` CLI.
Extracts and assigns COSMIC v3.4 mutational signatures (84 SBS / 11 DBS / 18 ID / 24 CN / 16 SV) from somatic VCFs using SigProfilerSuite, MutationalPatterns, MuSiCal mvNMF,…
Convert text to speech audio using OpenAI TTS-1-HD through the verging.ai proxy API. Supports multiple voices, playback speed control, and various audio output formats.
Filter and prioritize variants by pathogenicity, population frequency, and clinical evidence for rare disease analysis.
Generate AI videos with Google Veo, Seedance, Wan, Grok and 40+ models via inference.sh CLI. Models: Veo 3.1, Veo 3, Seedance 1.5 Pro, Wan 2.5, Grok Imagine Video, OmniHu — from…
XCMS3 workflow for LC-MS/MS metabolomics preprocessing. Covers peak detection, retention time alignment, correspondence (grouping), and gap filling.
Use when creating or developing anything, before writing code or implementation plans - refines rough ideas into fully-formed designs through structured Socratic questioning,…
Complete App Store Optimization (ASO) toolkit for researching, optimizing, and tracking mobile app performance on Apple App Store and Google Play Store — from bg-szy/TOP-SKILLS
Analyze cell-cell communication in spatial transcriptomics data using ligand-receptor analysis with Squidpy.
Automate Twitter/X with posting, engagement, and user management via inference.sh CLI. Apps: x/post-tweet, x/post-create (with media), x/post-like, x/post-retweet, x/dm-s — from…
Plot per-gene mutation distributions on a protein-domain map (lollipop / needle plots) showing mutation position, recurrence count, and variant classification with maftools,…
Detect introgression and admixture between species or populations using Dsuite (Malinsky 2021 fast D-statistics), Patterson's D / ABBA-BABA test (Green 2010; Durand 2011) — from…
Applies Anthropic's official brand colors and typography to any sort of artifact that may benefit from having Anthropic's look-and-feel.
Import transcript-level quantifications from Salmon/kallisto into R for gene-level analysis with DESeq2/edgeR using tximport or tximeta.
UI design system toolkit for Senior UI Designer including design token generation, component documentation, responsive design calculations, and developer handoff tools.
Chart selection and data visualization guidance for effective data communication. Use when: creating visualizations, choosing chart types, designing dashboards, or when user…
Use when you have a written implementation plan to execute in a separate session with review checkpoints — from bg-szy/TOP-SKILLS
Automated cell type annotation using reference-based methods including CellTypist, scPred, SingleR, and Azimuth for consistent, reproducible cell labeling.
Single-cell ATAC-seq analysis with Signac (R/Seurat) and ArchR. Process 10X Genomics scATAC data, perform QC, dimensionality reduction, clustering, peak calling, and moti — from…
Drive an authorized repository change through a verified local loop: baseline, reproduce, implement, test, review, and report evidence.
Comprehensive document creation, editing, and analysis with support for tracked changes, comments, formatting preservation, and text extraction.
Retrieves chemical compound information from PubChem and ChEMBL with disambiguation, cross-referencing, and quality assessment.
Stream-JSON chaining for multi-agent pipelines, data transformation, and sequential workflows — from bg-szy/TOP-SKILLS
Predict enhancer-gene regulatory connections from ATAC-seq using ABC, ENCODE-rE2G, HiChIP, or Cicero.
Creates reproducible Jupyter notebooks for bioinformatics analysis with parameterization using papermill.
Two services in one skill: (1) Web3 on-chain data via Chainbase CLI — use when the user asks about blockchain data, token holders, wallet addresses, token prices, ENS dom — from…
Find Reddit threads where people are genuinely asking for what you offer, then draft short, genuinely helpful replies — disclosing your affiliation honestly and naming your…
Search arXiv preprint repository for papers in physics, mathematics, computer science, quantitative biology, and related fields — from bg-szy/TOP-SKILLS
Authorization system with role-based access control. Must-have for all apps that manage personal or access-restricted data.
Browser automation for AI agents via inference.sh. Navigate web pages, interact with elements using @e refs, take screenshots, record video.
Differential abundance and state analysis for cytometry data. Compare cell populations between conditions using statistical methods.
Remote control tmux sessions for interactive CLIs, background tasks, and services. Supports sub-tasks, long-running processes, and service management with session persistence and…
A skill to evaluate how secure Firestore security rules are. Use this when Firestore security rules are updated to ensure that the generated rules are extremely secure an — from…
Review UI code for Web Interface Guidelines compliance. Use when asked to "review my UI", "check accessibility", "audit design", "review UX", or "check my site against be — from…
Perform pairwise sequence alignment using Biopython Bio.Align.PairwiseAligner. Use when comparing two sequences, finding optimal alignments, scoring similarity, and ident — from…
Game design principles. GDD structure, balancing, player psychology, progression. — from bg-szy/TOP-SKILLS
Configure, adjust, debug, and verify React Flow workflow nodes. Use when working on custom node components, especially for node handles, multi-channel connections, edge…
Create publication-ready volcano plots with custom thresholds, gene labels, and highlighting using ggplot2, EnhancedVolcano, or matplotlib.
Web search and content extraction with Tavily and Exa via inference.sh CLI. Apps: Tavily Search, Tavily Extract, Exa Search, Exa Answer, Exa Extract.
Build spatial neighbor graphs for spatial transcriptomics data using Squidpy. Compute k-nearest neighbors, Delaunay triangulation, and radius-based connectivity for downs — from…
Myeloproliferative neoplasm (MPN) research expertise including JAK2/CALR/MPL mutations, myelofibrosis, polycythemia vera, essential thrombocythemia.
Choose RouterBase model IDs and routing strategies for chat, image, video, audio, and embeddings workloads.
Normalize indel representation and split multiallelic variants using bcftools norm. Use when comparing variants from different callers or preparing VCF for downstream ana — from…
Comprehensive spreadsheet creation, editing, and analysis with support for formulas, formatting, data analysis, and visualization.
Assigns GO terms, Pfam/InterPro domains, KEGG orthologs, EC numbers, and product names to predicted proteins using eggNOG-mapper (orthology), InterProScan (domain signatures), and…
Create scalable, containerized bioinformatics pipelines with Nextflow DSL2 supporting Docker, Singularity, and cloud execution.
Generate images with Alibaba Qwen-Image-2.0-Pro via inference.sh CLI. Professional text rendering, fine-grained realism, enhanced semantic adherence.
Create commit messages following Sentry conventions. Use when committing code changes, writing commit messages, or formatting git history.
Generate images with Google Gemini 3.1 Flash Image Preview (Nano Banana 2) via inference.sh CLI. Capabilities: text-to-image, image editing, multi-image input (up to 14 i — from…
When the user wants to choose or execute third-party platform SEO (high-authority sites for rankings or backlinks).
Use when you have a spec or requirements for a multi-step task, before touching code — from bg-szy/TOP-SKILLS
Use when completing tasks, implementing major features, or before merging to verify work meets requirements - dispatches code-reviewer subagent to review implementation a — from…
Design LLM applications using the LangChain framework with agents, memory, and tool integration patterns.
Plot per-group distributions of continuous data using boxplots, violins, beeswarms, quasirandom jitter, and raincloud plots with sample-size honesty (Weissgerber 2015),…
Map metabolites to biological pathways using KEGG, Reactome, and MetaboAnalyst. Perform pathway enrichment and topology analysis.
Expert at TSDoc comments, Storybook stories, VitePress docs, TypeDoc API generation. Use when documenting code, adding comments, creating stories, or generating API docs.
Species abundance estimation using Bracken with Kraken2 output. Redistributes reads from higher taxonomic levels to species for more accurate estimates.