Invoke external AI CLIs via native Task agents (Claude, Codex, Gemini, Cursor). Primary mode for multi-provider orchestration with fork-terminal fallback for auth.
Use when you have a written implementation plan to execute in a separate session with review checkpoints — from bg-szy/TOP-SKILLS
DNA methylation analysis with methylKit in R. Import Bismark coverage files, filter by coverage, normalize samples, and perform statistical comparisons.
Product marketing, positioning, GTM strategy, and competitive intelligence. Includes ICP definition, April Dunford positioning methodology, launch playbooks, competitive — from…
Detect and analyze adverse drug event signals using FDA FAERS data, drug labels, disproportionality analysis (PRR, ROR, IC), and biomedical evidence.
Implements authentication and payment features using Clerk, Supabase Auth, or Stripe. Use when user mentions ログイン, 認証, auth, authentication, Clerk, Supabase, 決済, payment, Stripe,…
Balance, normalize, and transform Hi-C contact matrices using cooler and cooltools. Apply iterative correction (ICE), compute expected values, and generate observed/expec — from…
Create publication-quality scientific diagrams using Nano Banana Pro AI with smart iterative refinement. Uses Gemini 3 Pro for quality review.
Build a complete typographic system -- modular or fluid type scale, line-height and tracking per size, weight roles, and vertical rhythm -- exported as tokens, Tailwind config,…
Use when starting feature work that needs isolation from current workspace or before executing implementation plans - creates isolated git worktrees with smart directory — from…
Write and maintain Architecture Decision Records (ADRs) following best practices for technical decision documentation.
When the user wants to create competitor comparison or alternative pages for SEO and sales enablement.
UI 样式修改协作流程。当用户要求修改页面样式、调整布局、改 UI 细节时使用。通过"截图定位 → 现状描述 → 方案选择 → 改代码 → 微调"的结构化流程，减少沟通偏差，避免浪费 token。 — from bg-szy/TOP-SKILLS
Create, list, and apply Stitch design systems from DESIGN.md using the verified Stitch MCP design-system tools and safe upload fallbacks.
Use when Codex, Hermes, OpenClaw, Claude Code, Cowork, or another AI agent needs to plan, review, implement, audit, or improve email work focused on open, inspectable ema — from…
Use when facing 3+ independent failures that can be investigated without shared state or dependencies - dispatches multiple Claude agents to investigate and fix independe — from…
Excel (.xlsx) manipulation via MCP server. Use for creating workbooks, formatting cells, writing formulas, building charts, pivot tables, data analysis, or any task involving…
Transform data into compelling narratives using visualization, context, and persuasive structure. Use when presenting analytics to stakeholders, creating data reports, or — from…
Comprehensive guide for integrating Obsidian vaults as AI-powered second brains with Claude Code. Covers MCP integration, vault manifests, self-evolving patterns, auto-linking,…
Calculate translation efficiency (TE) as the ratio of ribosome occupancy to mRNA abundance. Use when comparing translational regulation between conditions or identifying — from…
Design LLM applications using the LangChain framework with agents, memory, and tool integration patterns.
Systematically evaluate scholarly work using the ScholarEval framework, providing structured assessment across research quality dimensions including problem formulation — from…
JACKS (Joint Analysis of CRISPR/Cas9 Knockout Screens) for modeling sgRNA efficacy and gene essentiality.
Visualize spatial transcriptomics data using Squidpy and Scanpy. Create tissue plots with gene expression, clusters, and annotations overlaid on histology images.
Load, convert, and manipulate Hi-C contact matrices using cooler format. Read .cool/.mcool files, convert from .hic format, access matrix data, and export to different fo — from…
Edit images with Flux 1 Kontext Pro (Black Forest Labs' precise local image-edit model) on RunComfy — bundled with the model's documented prompting patterns so the skill — from…
Specialized lipidomics analysis for lipid identification, quantification, and pathway interpretation.
When the user wants to add, optimize, or audit table of contents (TOC) for long-form content. Also use when the user mentions "TOC," "table of contents," "table of contents for…
Data-independent acquisition (DIA) proteomics analysis with DIA-NN and other tools. Use when analyzing DIA mass spectrometry data with library-free or library-based workf — from…
End-to-end TCR/BCR repertoire analysis from FASTQ to clonotype diversity metrics. Use when analyzing immune repertoire sequencing data from bulk or single-cell experiment — from…
Access COSMIC cancer mutation database. Query somatic mutations, Cancer Gene Census, mutational signatures, gene fusions, for cancer research and precision oncology.
Download raw sequencing reads from NCBI SRA using sra-tools (prefetch, fasterq-dump, vdb-validate) or the ENA mirror.
Generate and edit images on RunComfy via the `runcomfy` CLI — a smart router across the full image-model catalog: FLUX 2 (Klein 9B/4B, Pro, Dev, Flash, Turbo, Max), Googl — from…
Create publication-quality visualizations of immune repertoire data including circos plots, clone tracking, diversity plots, and network graphs.
Comprehensive software architecture skill for designing scalable, maintainable systems using ReactJS, NextJS, NodeJS, Express, React Native, Swift, Kotlin, Flutter, Postg — from…
Use when working on Nuxt 4+ projects - provides server routes, file-based routing, middleware patterns, Nuxt-specific composables, and configuration with latest docs.
Merge, concatenate, sort, intersect, and subset VCF files using bcftools. Use when combining variant files, comparing call sets, or restructuring VCF data. — from bg-szy/TOP-SKILLS
Automate Google NotebookLM - create notebooks, add sources, generate podcasts/videos/quizzes, download artifacts.
Meta-skill for publication-ready figures. Use when creating journal submission figures requiring multi-panel layouts, significance annotations, error bars, colorblind-saf — from…
Cell segmentation from multiplexed tissue images. Covers deep learning (Cellpose, Mesmer) and classical approaches for nuclear and whole-cell segmentation.
Searches molecular libraries for substructure matches using SMARTS patterns with RDKit. Filters compounds by pharmacophore features, functional groups, or scaffold matche — from…
Relight a still image — change the lighting setup, color temperature, direction, or mood — on RunComfy via the `runcomfy` CLI.
When the user wants to create, optimize, or audit pricing page content and structure. Also use when the user mentions "pricing page," "pricing table," "plans," "subscription,"…
Guidance for distinctive, intentional visual design when building new UI or reshaping an existing one.
Token deep dive — info, OHLCV, holders, flows, flow intelligence, who bought/sold, DEX trades, PnL, perp trades, perp positions, perp PnL leaderboard.
Evaluates genome assembly quality across the three orthogonal axes - contiguity (QUAST auN/NG50/NGx, not bare N50), completeness (BUSCO/compleasm gene-space plus Merqury k-mer…
Expert guidance for integrating and building applications with shadcn/ui components, including component discovery, installation, customization, and best practices.
Automate Twitter/X with posting, engagement, and user management via inference.sh CLI. Apps: x/post-tweet, x/post-create (with media), x/post-like, x/post-retweet, x/dm-s — from…
Review a feature and enhance it with purposeful animations, micro-interactions, and motion effects that improve usability and delight. — from bg-szy/TOP-SKILLS
Generate AI images with GPT-Image-2, FLUX, Gemini, Grok, Seedream, Reve and 50+ models via inference.sh CLI.
When the user wants to optimize post-signup onboarding, user activation, first-run experience, or time-to-value.
Fast miRNA quantification with isomiR detection and A-to-I editing analysis using miRge3. Use when quantifying known miRNAs quickly or analyzing isomiR variants and RNA e — from…
Tests genotype-environment associations and identifies adaptive loci while correcting for the four-confound landscape (structure, demography, background selection, sampling…
Use when preparing the narrative, sources, and design context for a new editable PPTX deck.
Generate text-to-video with HappyHorse 1.0 on RunComfy. Documents HappyHorse 1.0's strengths (#1 on Artificial Analysis Video Arena, native 1080p with in-pass synchronize — from…
Video outpainting on RunComfy via the `runcomfy` CLI — extend the spatial canvas of a video, change aspect ratio (9:16 vertical to 16:9 horizontal or vice versa), add env — from…
Generate images with Google Gemini 3.1 Flash Image Preview (Nano Banana 2) via inference.sh CLI. Capabilities: text-to-image, image editing, multi-image input (up to 14 i — from…
When the user wants to plan, implement, or optimize discount and promotional pricing strategy. Also use when the user mentions "discount strategy," "promo code," "coupon," "redeem…
Use when an agent hits HTTP 402 / payment-required, or the user mentions x402, x402Version, X-PAYMENT, PAYMENT-REQUIRED, PAYMENT-SIGNATURE, WWW-Authenticate: Payment, per — from…
Analyze multi-modal single-cell data (CITE-seq, Multiome, spatial). Use when working with data that measures multiple modalities per cell like RNA + protein or RNA + ATAC — from…