CRISPR library design for genetic screens. Covers sgRNA selection, library composition, control design, and oligo ordering.
Automatically organizes invoices and receipts for tax preparation by reading messy files, extracting key information, renaming them consistently, and sorting them into lo — from…
Write biological sequences to files (FASTA, FASTQ, GenBank, EMBL) using Biopython Bio.SeqIO. Use when saving sequences, creating new sequence files, or outputting modifie — from…
Reconstruct ancestral states at internal phylogenetic nodes for sequences (PAML codeml, IQ-TREE --ancestral, GRASP, FastML), discrete traits (corHMM hidden-rate Markov, ape::ace,…
Interactive cell type annotation for IMC data. Covers napari-based annotation, marker-guided labeling, training data generation, and annotation validation.
Quality control, filtering, normalization, and feature selection for spatial transcriptomics data. Calculate QC metrics, filter spots/cells, normalize counts, and identif — from…
Cloud laboratory platform for automated protein testing and validation. Use when designing proteins and needing experimental validation including binding assays, expressi — from…
Use when the user asks for SOP and Process Training from supplied source materials. Trigger language: SOP training; process training; procedure training; policy training.
Generate AI videos with Google Veo, Seedance, Wan, Grok and 40+ models via inference.sh CLI. Models: Veo 3.1, Veo 3, Seedance 1.5 Pro, Wan 2.5, Grok Imagine Video, OmniHu — from…
Pythonic wrapper around RDKit with simplified interface and sensible defaults. Preferred for standard drug discovery including SMILES parsing, standardization, descriptor — from…
Frontend development guidelines for React/TypeScript applications. Modern patterns including Suspense, lazy loading, useSuspenseQuery, file organization with features dir — from…
Run 250+ AI apps via inference.sh CLI - image generation, video creation, LLMs, search, 3D, Twitter automation.
Build production Apache Airflow DAGs with best practices for operators, sensors, testing, and deployment.
Pose-conditioned generation on RunComfy via the `runcomfy` CLI. Routes across Kling 2-6 Motion Control Pro / Standard (transfer the motion / blocking of a reference video — from…
Write effective blameless postmortems with root cause analysis, timelines, and action items. Use when conducting incident reviews, writing postmortem documents, or improving…
Notion workspace management via MCP - create databases, pages, comments, and knowledge bases. Use when building Notion documentation, organizing project wikis, or managing Notion…
Build maximum likelihood phylogenetic trees using IQ-TREE2 and RAxML-NG with expert model selection, branch support assessment, and topology testing.
Taxonomic classification of metagenomic reads using Kraken2. Fast k-mer based classification against RefSeq database.
Create portable, standards-based bioinformatics pipelines with Common Workflow Language (CWL). Use when building workflows that need maximum portability across execution — from…
Help Claude query STRING for protein interactions, build PPI graphs with pyPPI, and render styled network figures for bulk gene lists. — from bg-szy/TOP-SKILLS
ERC-8004 Trustless Agents for on-chain agent identity and reputation. Resolve an agent by ID from the Identity Registry ERC-721 to its owner and AgentCard, list canonical registry…
Create 3D data visualizations using Swift Charts. Use when the user wants to create a 3D chart, asks about Chart3D or SurfacePlot, needs interactive drag-to-rotate, or wants…
Pull pre-computed ortholog calls from public databases (OrthoDB, Ensembl Compara, OMA browser, eggNOG, PANTHER, KEGG Orthology, HomoloGene) via their REST APIs.
Infers person-to-person transmission from pathogen genomes using outbreaker2 (Campbell 2018), TransPhylo (Didelot 2017), phybreak (Klinkenberg 2017), BadTrIP (De Maio 2018),…
Applies Anthropic's official brand colors and typography to any sort of artifact that may benefit from having Anthropic's look-and-feel.
A fast Rust-based headless browser automation CLI with Node.js fallback that enables AI agents to navigate, click, type, and snapshot pages via structured commands.
UI/UX design intelligence. 50 styles, 21 palettes, 50 font pairings, 20 charts, 9 stacks (React, Next.js, Vue, Svelte, SwiftUI, React Native, Flutter, Tailwind, shadcn/ui — from…
Generate AI images with GPT-Image-2, FLUX, Gemini, Grok, Seedream, Reve and 50+ models via inference.sh CLI.
Deep generative models for single-cell omics. Use when you need probabilistic batch correction (scVI), transfer learning, differential expression with uncertainty, or mul — from…
Guides creation of effective Agent Skills with proper structure and validation. Use when users want to create a new skill, update an existing skill, or need guidance on s — from…
Quality metrics for IMC data including signal-to-noise, channel correlation, tissue integrity, and acquisition QC.
MUST be used for Vue.js tasks. Strongly recommends Composition API with `<script setup>` and TypeScript as the standard approach. Covers Vue 3, SSR, Volar, vue-tsc.
Specialized knowledge of Bash and Zsh scripting, shell automation, command-line tools, and scripting best practices.
Generates the storyboard sheets for a video — one image per clip, panels in a row, each panel one action.
Presentation creation, editing, and analysis. When Claude needs to work with presentations (.pptx files) for: (1) Creating new presentations, (2) Modifying or editing con — from…
Drive Chromium from standard Playwright APIs with a real-device fingerprint applied inside the browser kernel, one persistent isolated profile per identity, and a per-profile…
World-class ML engineering skill for productionizing ML models, MLOps, and building scalable ML systems.
Mask-driven image inpainting on RunComfy via the `runcomfy` CLI. Routes to Tongyi MAI Z-Image Turbo Inpainting (the dedicated inpainting endpoint with mask, strength, and — from…
Guide Claude through omicverse's single-cell clustering workflow, covering preprocessing, QC, multimethod clustering, topic modeling, cNMF, and cross-batch integration as — from…
Calls HLA class I and class II alleles at 2/4/6/8-field resolution from WGS/WES/RNA-seq/long-read data using OptiType, HLA-LA, T1K, Polysolver, HLA-HD, arcasHLA, StarPhase, or…
Comprehensive security auditing workflow covering web application testing, API security, penetration testing, vulnerability scanning, and security hardening.
When the user wants to create, optimize, or audit a product listing or category page. Also use when the user mentions "product page," "product listing," "shop," "e-commerce…
Automate Twitter/X with posting, engagement, and user management via inference.sh CLI. Apps: x/post-tweet, x/post-create (with media), x/post-like, x/post-retweet, x/dm-s — from…
When the user wants to plan growth using the AARRR framework, diagnose growth bottlenecks, or map actions across the customer lifecycle.
Toolkit for interacting with and testing local web applications using Playwright. Supports verifying frontend functionality, debugging UI behavior, capturing browser scre — from…
Automated LLM-driven hypothesis generation and testing on tabular datasets. Use when you want to systematically explore hypotheses about patterns in empirical data (e.g — from…
Generate, inpaint, and outpaint music with ACE Step on RunComfy via the `runcomfy` CLI. ACE Step is StepFun-AI's open-weights music foundation model — tag-driven composit — from…
Robusta Kubernetes observability and alert automation platform. USE WHEN installing Robusta OR configuring playbooks OR setting up notification sinks OR troubleshooting Kubernetes…
Profiles non-miRNA small RNAs - tRNA-derived fragments (tRFs/tsRNAs), piRNAs, and rRNA/snoRNA-derived species - with MINTmap, unitas, SPORTS, and proTRAC.
Use when the user asks for Product First-Success Guide from supplied source materials. Trigger language: product setup; getting started; quick start guide; first successful use.
Profiles RNA-binding protein targets without antibody or UV crosslinking using STAMP (APOBEC1-RBP fusion, C-to-U editing), scSTAMP (single-cell), TRIBE/HyperTRIBE (ADAR-RBP,…
Create and edit JSON Canvas files (.canvas) with nodes, edges, groups, and connections. Use when working with .canvas files, creating visual canvases, mind maps, flowchar — from…
Generate AI videos with Google Veo, Seedance, Wan, Grok and 40+ models via inference.sh CLI. Models: Veo 3.1, Veo 3, Seedance 1.5 Pro, Wan 2.5, Grok Imagine Video, OmniHu — from…
Audit a landing page, sales page or checkout page for conversion leaks and return a fix list ordered by expected revenue impact.
Profiles a genome from raw reads BEFORE assembly with a k-mer spectrum (KMC or Jellyfish histogram), then models it with GenomeScope2 to estimate genome size, heterozygosity,…
UI/UX design intelligence. 50 styles, 21 palettes, 50 font pairings, 20 charts, 9 stacks (React, Next.js, Vue, Svelte, SwiftUI, React Native, Flutter, Tailwind, shadcn/ui — from…
When the user wants to validate product-market fit, measure PMF, or plan before scaling. Also use when the user mentions "PMF," "product-market fit," "product market fit," "Sean…
Detect and remove doublets (two or more cells in one droplet) from single-cell RNA-seq using scDblFinder (R), Scrublet (Python), and DoubletFinder (R).
Create new skills, modify and improve existing skills, and measure skill performance. Use when users want to create a skill from scratch, edit, or optimize an existing sk — from…
A relentless interview that asks every frontier question at once, round by round.