Discovers de novo motifs and tests known motif enrichment in ChIP-seq, ATAC-seq, or other peak sequences using HOMER, MEME-ChIP (STREME, CentriMo, TOMTOM, FIMO), monaLisa, and…
Performs differential expression on bulk RNA-seq count data with edgeR's negative-binomial GLM and quasi-likelihood F-test framework.
Automated coordination, formatting, and learning from Claude Code operations using intelligent hooks with MCP integration.
When the user wants to create, optimize, or audit e-commerce category pages or listing pages. Also use when the user mentions "category page," "product category," "faceted…
Apply behavioral science and mental models to marketing decisions, prioritized using a psychological leverage and feasibility scoring system. — from bg-szy/TOP-SKILLS
Vendor-agnostic lab automation framework. Use when controlling multiple equipment types (Hamilton, Tecan, Opentrons, plate readers, pumps) or needing unified programming — from…
Search NCBI databases using Biopython Bio.Entrez (ESearch, EInfo, EGQuery, ESpell). Use when finding records by keyword, building reproducible field-qualified queries, navigating…
When the user wants to create, optimize, or audit 404 error pages. Also use when the user mentions "404 page," "404 error," "error page," "page not found," "broken link page,"…
Builds and applies 3D pharmacophore models using RDKit Pharm3D, the apo2ph4 receptor-based workflow (Heider et al 2022/2023 J Chem Inf Model 63:147-158), Pharmer / Pharmit…
Navigate protein structure hierarchy using Biopython Bio.PDB SMCRA model. Use when accessing models, chains, residues, and atoms, iterating over structure levels, or extr — from…
Gather comprehensive biological target intelligence from 9 parallel research paths covering protein info, structure, interactions, pathways, expression, variants, drug…
Comprehensive guide for building Model Context Protocol (MCP) servers with support for tools, resources, prompts, and authentication.
Edit images with Google Nano Banana 2 (image-to-image edit endpoint) on RunComfy. Documents Nano Banana Edit's strengths (preserve subject identity, swap background, loca — from…
Performs structure-based virtual screening using AutoDock Vina 1.2 for molecular docking. Prepares receptor PDBQT files, generates ligand conformers, defines binding site boxes,…
Calls microsatellite instability from WES/WGS/targeted-panel with MSIsensor, MSIsensor-pro, MSIsensor-ct (panel-aware), MSIngs, MANTIS, MSIPanel, MSIDetect, and ngsMSI for FDA…
Perform comprehensive gene enrichment and pathway analysis using gseapy (ORA and GSEA), PANTHER, STRING, Reactome, and 40+ ToolUniverse tools.
Interactive cell type annotation for IMC data. Covers napari-based annotation, marker-guided labeling, training data generation, and annotation validation.
Create publication-quality visualizations of immune repertoire data including circos plots, clone tracking, diversity plots, and network graphs.
Build end-to-end MLOps pipelines from data preparation through model training, validation, and production deployment.
Federated variant lookup across 9 genomic databases — GWAS Catalog, Open Targets, PheWeb (UKB, FinnGen, BBJ), GTEx, eQTL Catalogue, and more.
Multi-objective optimization framework. NSGA-II, NSGA-III, MOEA/D, Pareto fronts, constraint handling, benchmarks (ZDT, DTLZ), for engineering design and optimization pro — from…
Detect introgression and admixture between species or populations using Dsuite (Malinsky 2021 fast D-statistics), Patterson's D / ABBA-BABA test (Green 2010; Durand 2011) — from…
Create comprehensive API documentation for developers. Use when documenting REST APIs, GraphQL schemas, or SDK methods.
Quality metrics for IMC data including signal-to-noise, channel correlation, tissue integrity, and acquisition QC.
Impute missing genotypes using reference panels with Beagle or Minimac4. Use when increasing variant density for GWAS, harmonizing data across genotyping platforms, or in — from…
Perform flux balance analysis (FBA) and flux variability analysis (FVA) on genome-scale metabolic models using COBRApy.
Search FDA drug labels with natural language queries. Official drug information, indications, and safety data via Valyu.
Evaluates genome assembly quality across the three orthogonal axes - contiguity (QUAST auN/NG50/NGx, not bare N50), completeness (BUSCO/compleasm gene-space plus Merqury k-mer…
When the user wants to plan, implement, or optimize employee-generated content (EGC) or employee advocacy.
When the user wants to create, optimize, or audit a startups, education, or special program page. Also use when the user mentions "startups program," "for startups," "education…
Production-ready genomics and epigenomics data processing for BixBench questions. Handles methylation array analysis (CpG filtering, differential methylation, age-related CpG…
Identifies essential genes from CRISPR-Cas9 fitness screens using BAGEL2 (Kim & Hart 2021 Genome Med), a Bayesian classifier scoring per-gene Bayes Factors via log-likelihood…
Create professional research posters in LaTeX using beamerposter, tikzposter, or baposter. Support for conference presentations, academic posters, and scientific communic — from…
Next.js 16.2.4 with TypeScript — App Router, Server Components, use cache directive, Turbopack dev, Server Actions, ISR, SSR, SSG, MCP devtools, metadata API, route handlers,…
Estimate divergence times using molecular clock models with BEAST2, MCMCTree, and TreePL. Use when dating speciation events, calibrating phylogenies with fossils, choosing between…
Designs and analyzes pooled prime-editor (PE) screens for installing precise genetic variants without bystander confounding.
Design robust, scalable database schemas for SQL and NoSQL databases. Provides normalization guidelines, indexing strategies, migration patterns, constraint design, and p — from…
Diffusion-based molecular docking. Predict protein-ligand binding poses from PDB/SMILES, confidence scores, virtual screening, for structure-based drug design.
Build Manhattan, Miami, QQ, and locuszoom-style regional plots from GWAS, TWAS, PWAS, and QTL summary statistics with correct genomic-inflation diagnostics, multi-trait overlays,…
Analyze BCR repertoires for somatic hypermutation, clonal lineages, and B cell phylogenetics using the Immcantation framework.
Next-generation sequencing data analysis pipelines including bulk RNA-seq, scRNA-seq preprocessing, variant calling, and quality control.
Generate AI images with FLUX, Gemini, Grok, Seedream, Reve and 50+ models via inference.sh CLI. Models: FLUX Dev LoRA, FLUX.2 Klein LoRA, Gemini 3 Pro Image, Grok Imagine — from…
When the user wants to create, optimize, or audit blog index or listing page structure (not a single post).
Implement comprehensive observability for service meshes including distributed tracing, metrics, and visualization.
Detects differential alternative splicing between conditions using rMATS-turbo (BAM-based) or SUPPA2 diffSplice (TPM-based).
Browser automation for AI agents via inference.sh. Navigate web pages, interact with elements using @e refs, take screenshots, record video.
When the user wants to run paid ads within directories or marketplaces. Also use when the user mentions "Taaft ads," "Shopify App Store ads," "G2 sponsored," "Capterra ads,"…
Sequence-based deep learning for ATAC-seq using chromBPNet, BPNet, scBasset, or EnFormer. Use when correcting Tn5 bias with neural networks beyond k-mer models, predicting…
Comprehensive document creation, editing, and analysis with support for tracked changes, comments, formatting preservation, and text extraction.
Specialized lipidomics analysis for lipid identification, quantification, and pathway interpretation.
When the user wants to create, optimize, or audit glossary page content and structure. Also use when the user mentions "glossary," "definitions," "terminology," "industry terms,"…
When the user wants to choose or optimize rendering strategy for SEO. Also use when the user mentions "SSR," "SSG," "CSR," "ISR," "static rendering," "dynamic rendering,"…
UI/UX design intelligence. 50 styles, 21 palettes, 50 font pairings, 20 charts, 9 stacks (React, Next.js, Vue, Svelte, SwiftUI, React Native, Flutter, Tailwind, shadcn/ui — from…
Calculates molecular fingerprints (ECFP/Morgan, FCFP, MACCS, RDKit, AtomPair, TopologicalTorsion, Avalon, MAP4, MHFP6) and physicochemical descriptors (Lipinski, QED, TPSA,…
Professional brand consistency enforcement and corporate identity management with support for color palettes, typography, logo usage, tone of voice, and multi-channel brand…
When the user wants to create, optimize, or audit a services page. Also use when the user mentions "services page," "what we offer," "service offerings," "consulting services,"…
Query the Ensembl REST API for gene/transcript/protein lookup, sequence retrieval, comparative genomics (Compara), variant effect prediction (VEP), regulatory features, and…
Cross-method decision tree for calling hits in pooled CRISPR screens. Catalogs statistical models (MAGeCK RRA, MAGeCK MLE, BAGEL2, drugZ, JACKS, Chronos, CERES), experimental…
Search arXiv preprint repository for papers in physics, mathematics, computer science, quantitative biology, and related fields — from bg-szy/TOP-SKILLS
Generate alignment statistics using samtools flagstat, stats, depth, coverage, and mosdepth. Use when assessing alignment quality, calculating coverage, or generating QC reports.