Review final-assignment materials for requirements, citations, AI-use disclosure, and data-analysis completeness.
Guide to reproducing OmicVerse trajectory workflows spanning PAGA, Palantir, VIA, velocity coupling, and fate scoring notebooks. — from bg-szy/TOP-SKILLS
Generate images with Flux 2 Klein (Black Forest Labs' distilled fast variant of Flux 2) on RunComfy — bundled with the model's documented prompting patterns so the skill — from…
Review a feature and enhance it with purposeful animations, micro-interactions, and motion effects that improve usability and delight. — from bg-szy/TOP-SKILLS
Lip-sync a face to a specific audio track on RunComfy via the `runcomfy` CLI. Routes across ByteDance OmniHuman (audio-driven full-body avatar from a portrait + audio), S — from…
Hardware-agnostic quantum ML framework with automatic differentiation. Use when training quantum circuits via gradients, building hybrid quantum-classical models, or need — from…
Build Sankey, alluvial, river, and CONSORT-style flow diagrams to visualize cohort transitions, cell-state changes, or pipeline filtering using ggalluvial, networkD3, plotly, and…
Configure mutual TLS (mTLS) for zero-trust service-to-service communication. Use when implementing zero-trust networking, certificate management, or securing internal ser — from…
Estimates circulating tumor DNA fraction from shallow whole-genome sequencing using ichorCNA. Detects copy number alterations via HMM segmentation and calculates ctDNA pe — from…
Use when starting any conversation - establishes how to find and use skills, requiring Skill tool invocation before ANY response including clarifying questions — from…
Create scalable, containerized bioinformatics pipelines with Nextflow DSL2 supporting Docker, Singularity, and cloud execution.
ATAC-seq library quality control -- TSS enrichment, FRiP, fragment-size periodicity, library complexity (NRF/PBC1/PBC2), mitochondrial fraction, and ENCODE 4 thresholds.
Detect transcription factor binding footprints in ATAC-seq using TOBIAS, HINT-ATAC, Wellington, or scprinter.
Builds and applies 3D pharmacophore models using RDKit Pharm3D, the apo2ph4 receptor-based workflow (Heider et al 2022/2023 J Chem Inf Model 63:147-158), Pharmer / Pharmit…
YouTube thumbnail design with specific dimensions, contrast rules, and mobile preview optimization. Covers safe zones, text placement, face expression psychology, and A/B — from…
Provides thorough code review guidance when users ask for code reviews, PR reviews, or feedback on their code.
Produce and interpret PCA, t-SNE, UMAP, and PHATE plots for high-dimensional omics data with rigor about which method preserves what (variance, local structure, manifold,…
Convert approved Stitch exports into accessible React and Vite dashboards with DESIGN.md tokens, TanStack Query data boundaries, responsive layouts, and optional read-only Web3…
Predicts ADMET properties using ADMETlab 3.0 (119 endpoints with uncertainty), ADMET-AI, DeepChem MolNet, and chemprop D-MPNN with explicit handling of OECD QSAR principles,…
Query the Ensembl REST API for gene/transcript/protein lookup, sequence retrieval, comparative genomics (Compara), variant effect prediction (VEP), regulatory features, and…
Create structured incident response runbooks with step-by-step procedures, escalation paths, and recovery actions.
Use when implementing any feature or bugfix, before writing implementation code - write the test first, watch it fail, write minimal code to pass; ensures tests actually — from…
Tests whether two genomic interval sets overlap (colocalize) more than expected by chance using a permutation test against a structured-genome null model.
Image outpainting on RunComfy via the `runcomfy` CLI — extend a still beyond its original canvas, fill in what the camera didn't capture, change aspect ratio (square → 16 — from…
Differential abundance testing for microbiome data using compositionally-aware methods like ALDEx2, ANCOM-BC2, and MaAsLin2.
Run 250+ AI apps via inference.sh CLI - image generation, video creation, LLMs, search, 3D, Twitter automation.
Recognize patterns of context failure: lost-in-middle, poisoning, distraction, and clash
Use when implementation is complete, all tests pass, and you need to decide how to integrate the work - guides completion of development work by presenting structured opt — from…
Suite of tools for creating elaborate, multi-component claude.ai HTML artifacts using modern frontend web technologies (React, Tailwind CSS, shadcn/ui).
Is this token held by quality wallets or retail noise? SM holder ratio, flow breakdown by label, and recent buyer quality. — from bg-szy/TOP-SKILLS
Analyze high-resolution spatial platforms like Slide-seq, Stereo-seq, and Visium HD. Use when working with subcellular resolution or high-density spatial data.
Create commit messages following Sentry conventions. Use when committing code changes, writing commit messages, or formatting git history.
Calls ChIP-seq peaks with MACS3, MACS2, HOMER, or SPP across narrow (TF) and broad (histone) modes. Handles input control matching, fragment-size modeling vs --nomodel, effective…
Browser automation for AI agents via inference.sh. Navigate web pages, interact with elements using @e refs, take screenshots, record video.
Medicinal chemistry filters. Apply drug-likeness rules (Lipinski, Veber), PAINS filters, structural alerts, complexity metrics, for compound prioritization and library fi — from…
Query NHGRI-EBI GWAS Catalog for SNP-trait associations. Search variants by rs ID, disease/trait, gene, retrieve p-values and summary statistics, for genetic epidemiology — from…
Turn real customer reviews, quotes, and case-study results into polished social-proof videos built in HyperFrames -- single-testimonial spotlights, review-wall montages, and…
Analyzes CRISPR drug-modifier (chemogenomic) screens with drugZ (Li & Hart 2019 Genome Med), a bidirectional Z-score method that identifies synthetic-lethal sensitizing genes and…
Generate professional markdown and HTML reports from data with charts, tables, and analysis. — from bg-szy/TOP-SKILLS
Master Python asyncio, concurrent programming, and async/await patterns for high-performance applications.
Call topologically associating domains (TADs) from Hi-C data using insulation score, HiCExplorer, and other methods.
Migrate from AngularJS to Angular using hybrid mode, incremental component rewriting, and dependency injection updates.
Identify recurrent and driver copy number alterations across a tumor cohort with GISTIC2 (G-score, Ziggurat deconstruction, focal vs broad/arm-level analysis, q-values from…
Detect and adjust for horizontal pleiotropy in two-sample Mendelian randomization by distinguishing uncorrelated (UHP) from correlated (CHP) pleiotropy and choosing among Egger,…
Predict metagenome functional content from 16S rRNA marker gene data using PICRUSt2. Infer KEGG, MetaCyc, and EC abundances from ASV tables.
Deep generative models for single-cell omics. Use when you need probabilistic batch correction (scVI), transfer learning, differential expression with uncertainty, or mul — from…
Execute Python code in a safe sandboxed environment via [inference.sh](https://inference.sh). Pre-installed: NumPy, Pandas, Matplotlib, requests, BeautifulSoup, Selenium — from…
Give an AI agent its own real browser over MCP tool calls - launch, navigate, click, fill, screenshot, extract text, run JS - with a kernel-level real-device fingerprint and a…
Convert text to speech audio using OpenAI TTS-1-HD through the verging.ai proxy API. Supports multiple voices, playback speed control, and various audio output formats.
Cell-free DNA analysis pipeline from plasma sequencing to tumor monitoring. Preprocesses cfDNA reads, analyzes fragment patterns, estimates tumor fraction from sWGS, and — from…
Quality control of phasing and imputation results. Filter by INFO scores, assess accuracy, and prepare imputed data for downstream analysis.
Implement Kubernetes security policies including NetworkPolicy, PodSecurityPolicy, and RBAC for production-grade security.
API documentation workflow for generating OpenAPI specs, creating developer guides, and maintaining comprehensive API documentation. — from bg-szy/TOP-SKILLS
Presentation creation, editing, and analysis. When Claude needs to work with presentations (.pptx files) for: (1) Creating new presentations, (2) Modifying or editing con — from…
Analyzes base-editing screens for variant function. Covers library design (Sanson 2020 GRACE, Hanna 2021 BRCA1/2 SNV scanning, Cuella-Martin 2021), CBE vs ABE chemistry choice…
Designs and analyzes pooled prime-editor (PE) screens for installing precise genetic variants without bystander confounding.
Profiles non-miRNA small RNAs - tRNA-derived fragments (tRFs/tsRNAs), piRNAs, and rRNA/snoRNA-derived species - with MINTmap, unitas, SPORTS, and proTRAC.
Segments the genome into chromatin states from combinatorial histone modification and chromatin factor ChIP-seq data.
UI 样式修改协作流程。当用户要求修改页面样式、调整布局、改 UI 细节时使用。通过"截图定位 → 现状描述 → 方案选择 → 改代码 → 微调"的结构化流程，减少沟通偏差，避免浪费 token。 — from bg-szy/TOP-SKILLS
Web search and content extraction with Tavily and Exa via inference.sh CLI. Apps: Tavily Search, Tavily Extract, Exa Search, Exa Answer, Exa Extract.