When the user wants to create, optimize, or audit 404 error pages. Also use when the user mentions "404 page," "404 error," "error page," "page not found," "broken link page,"…
Builds classification models for omics data using RandomForest, XGBoost, and logistic regression with sklearn-compatible APIs.
Search FDA drug labels with natural language queries. Official drug information, indications, and safety data via Valyu.
Extracts and analyzes competitors' ads from ad libraries (Facebook, LinkedIn, etc.) to understand what messaging, problems, and creative approaches are working.
When the user wants to create, optimize, or audit signup and login pages. Also use when the user mentions "signup page," "login page," "registration page," "auth page," "sign up…
End-to-end metabolomics workflow from raw MS data to pathway analysis. Orchestrates XCMS preprocessing, annotation, normalization, statistical analysis, and pathway mappi — from…
When the user wants to plan, implement, or optimize employee-generated content (EGC) or employee advocacy.
Dimensionality reduction and clustering for single-cell RNA-seq using Seurat (R) and Scanpy (Python).
Identify direct miRNA-target interactions from AGO HITS-CLIP, AGO-CLEAR-CLIP (chimeric reads), HEAP (Halo-Ago2 mouse), chimeric eCLIP / miR-eCLIP (deep miRNA-target profiling), or…
Production-ready RNA-seq differential expression analysis using PyDESeq2. Performs DESeq2 normalization, dispersion estimation, Wald testing, LFC shrinkage, and result filtering.
Master monorepo management with Turborepo, Nx, and pnpm workspaces to build efficient, scalable multi-package repositories with optimized builds and dependency management.
Knowledge and utilities for creating animated GIFs optimized for Slack. Provides constraints, validation tools, and animation concepts.
Search ChEMBL bioactive molecules database with natural language queries. Find compounds and assay data with Valyu semantic search.
When the user wants to improve crawlability, fix orphan pages, or optimize site structure for search engines.
Applies Anthropic's official brand colors and typography to any sort of artifact that may benefit from having Anthropic's look-and-feel.
Designs Bayesian clinical trials including Phase I dose-finding (BOIN, CRM, EWOC, mTPI-2), meta-analytic-predictive (MAP) priors with robust mixtures for external data bo — from…
Use when the user asks for Employee Onboarding Course from supplied source materials. Trigger language: employee onboarding; new hire onboarding; new hire training; role ramp.
Quality control, filtering, normalization, and feature selection for spatial transcriptomics data. Calculate QC metrics, filter spots/cells, normalize counts, and identif — from…
Use when the user asks for Lead Magnet from supplied source materials. Trigger language: lead magnet; lead magnet ideas; free mini course; list building; interactive presentation.
Handles BED-format genomic intervals (BED3 through BED12, narrowPeak/broadPeak) and the coordinate-system substrate the whole interval category rests on, with bedtools (CLI) and…
JavaScript/TypeScript SDK for inference.sh - run AI apps, build agents, integrate 150+ models. Package: @inferencesh/sdk (npm install).
Generate commit message, PR title, and PR body for a pull request. Use when the user wants to create a PR, generate PR content, prepare a pull request, or fill a PR template from…
Build and analyze pangenomes for prokaryotes (Panaroo, PPanGGOLiN, PEPPAN, GET_HOMOLOGUES, anvi'o pangenomics) and eukaryotes (Minigraph-Cactus, PGGB, vg pangenome graphs).
Lip-sync a face to a specific audio track on RunComfy via the `runcomfy` CLI. Routes across ByteDance OmniHuman (audio-driven full-body avatar from a portrait + audio), S — from…
Browser automation for AI agents via inference.sh. Navigate web pages, interact with elements using @e refs, take screenshots, record video.
Design, deploy, and monitor a GenLayer Intelligent Oracle prediction market from any coding agent. Use when a user wants to create a settled-by-web-evidence prediction ma — from…
Use when you have a written implementation plan to execute in a separate session with review checkpoints — from bg-szy/TOP-SKILLS
Automate Twitter/X tasks via Rube MCP (Composio): posts, search, users, bookmarks, lists, media. Always search tools first for current schemas. — from bg-szy/TOP-SKILLS
Visualises RNA-modification data with transcript-feature metagene plots (Guitar GuitarPlot with 5'UTR / CDS / 3'UTR scaling; MetaPlotR; deepTools `computeMatrix scale-regions`),…
When the user wants to track AI search traffic in GA4 or GSC. Also use when the user mentions "AI traffic," "ChatGPT referral," "Perplexity traffic," "AI Overviews," "GA4 AI…
Search global patents with natural language queries. Prior art, patent landscapes, and innovation tracking via Valyu.
Trains and applies base-resolution deep learning models on ChIP-seq / ChIP-nexus / CUT&RUN data. Uses BPNet (Avsec 2021 Nat Genet 53:354; soft motif syntax from ChIP-nexus),…
Selects informative features for biomarker discovery using Boruta all-relevant selection, mRMR minimum redundancy, and LASSO regularization.
Low-level plotting library for full customization. Use when you need fine-grained control over every plot element, creating novel plot types, or integrating with specific…
Align RNA-seq reads with HISAT2, a memory-efficient splice-aware aligner. Use when STAR's memory requirements are too high or for general RNA-seq alignment.
Bulk-query Ensembl BioMart (and other BioMart instances) for cross-database ID mapping, gene/transcript/exon coordinates, and ortholog tables.
Designs and analyzes in vivo CRISPR screens in animal tumor models, organoids, and immune-cell adoptive transfers.
Assigns isolate identity at the right resolution for the question -- ANI / Mash species triage, 7-locus MLST historical comparability, cgMLST / wgMLST outbreak resolution…
Analyze protein-protein interaction networks using STRING, BioGRID, and SASBDB databases. Maps protein identifiers, retrieves interaction networks with confidence scores, performs…
Develop AI-powered applications using Genkit in Node.js/TypeScript. Use when the user asks about Genkit, AI agents, flows, or tools in JavaScript/TypeScript, or when enco — from…
Design durable workflows with Temporal for distributed systems. Covers workflow vs activity separation, saga patterns, state management, and determinism constraints.
Work with FASTQ quality scores using Biopython. Use when analyzing read quality, filtering by quality, trimming low-quality bases, or generating quality reports.
Search PubMed and bioRxiv, summarise papers with LLM, build citation graphs, and generate literature review sections.
Derive security requirements from threat models and business context. Use when translating threats into actionable requirements, creating security user stories, or buildi — from…
Create, list, read, message, wait on, fork, rename, archive, and pin Codex threads (sidebar tasks), plus automations and app navigation, using the app-native codex_app tools.
Performs 3D shape-based similarity searching using ROCS (OpenEye), USRCAT (ultra-fast), Open3DAlign (RDKit), ESPSim (electrostatic), and ShaEP with explicit handling of…
Assesses RNA-seq data quality for splicing analysis including junction saturation curves, splice site strength scoring, and junction coverage metrics using RSeQC.
When the user wants to optimize URL structure, fix URL issues, or plan URL hierarchy. Also use when the user mentions "URL structure," "URL optimization," "slug," "clean URLs,"…
Implement GitOps workflows with ArgoCD and Flux for automated, declarative Kubernetes deployments with continuous reconciliation.
Perform comprehensive audit of interface quality across accessibility, performance, theming, and responsive design.
Biological data toolkit. Sequence analysis, alignments, phylogenetic trees, diversity metrics (alpha/beta, UniFrac), ordination (PCoA), PERMANOVA, FASTA/Newick I/O, for m — from…
Similarity Network Fusion (SNF) for patient stratification using multi-omics data. Integrates multiple data types into a unified patient similarity network.
Analyze spatial transcriptomics data to map gene expression in tissue architecture. Supports 10x Visium, MERFISH, seqFISH, Slide-seq, and imaging-based platforms.
Profiles RNA-binding protein targets without antibody or UV crosslinking using STAMP (APOBEC1-RBP fusion, C-to-U editing), scSTAMP (single-cell), TRIBE/HyperTRIBE (ADAR-RBP,…
Review UI code for Web Interface Guidelines compliance. Use when asked to "review my UI", "check accessibility", "audit design", "review UX", or "check my site against be — from…
Access and analyze AlphaFold protein structure predictions. Use when predicted structures are needed for proteins without experimental structures, or for confidence score — from…
T-SQL, stored procedures, and MS SQL Server DBA practices. Use when writing SQL queries, designing schemas, tuning SQL Server performance, managing backups, configuring security,…
Read and write compressed sequence files (gzip, bzip2, BGZF) using Biopython. Use when working with .gz or .bz2 sequence files. Use BGZF for indexable compressed files.
Preprocesses cell-free DNA sequencing data including adapter trimming, alignment optimized for short fragments, and UMI-aware duplicate removal using fgbio.
Reads, writes, and converts molecular file formats (SMILES, SDF, MOL2, PDB) using RDKit and Open Babel.