Machine learning in Python with scikit-learn. Use when working with supervised learning (classification, regression), unsupervised learning (clustering, dimensionality reduction),…
Advanced GitHub Actions workflow automation with AI swarm coordination, intelligent CI/CD pipelines, and comprehensive repository management — from bg-szy/TOP-SKILLS
Build automated billing systems for recurring payments, invoicing, subscription lifecycle, and dunning management.
Create distributable Python packages with proper project structure, setup.py/pyproject.toml, and publishing to PyPI.
When the user wants to create, optimize, or structure a changelog or release notes page. Also use when the user mentions "changelog," "release notes," "what's new," "updates,"…
Master Bash Automated Testing System (Bats) for comprehensive shell script testing. Use when writing tests for shell scripts, CI/CD pipelines, or requiring test-driven de — from…
Perform pairwise sequence alignment using Biopython Bio.Align.PairwiseAligner. Use when comparing two sequences, finding optimal alignments, scoring similarity, and ident — from…
Comprehensive toolkit for creating, analyzing, and visualizing complex networks and graphs in Python.
Discover novel small molecule binders for protein targets using structure-based and ligand-based approaches.
Final visual polish for an existing UI without redesigning it. Use after structure is clear, when asked to improve spacing, alignment, text hierarchy, readability, shadows,…
Model gene-family birth-death dynamics across a species tree using CAFE5 (Mendes et al 2020 Bioinformatics 36:5516 gamma-distributed rate categories), CAFE5-error (annota — from…
MAGeCK (Model-based Analysis of Genome-wide CRISPR-Cas9 Knockout) for pooled CRISPR screen analysis. Covers count normalization, gene ranking, and pathway analysis.
When the user wants to optimize for mobile-first indexing or fix mobile usability. Also use when the user mentions "mobile-friendly," "mobile-first indexing," "mobile SEO,"…
Maps query single-cell data to reference atlases using scArches transfer learning with scVI and scANVI models.
UI design system toolkit for Senior UI Designer including design token generation, component documentation, responsive design calculations, and developer handoff tools.
Python research assistant with Context7 MCP. Use for Python library research, evaluating packages, enforcing strict Python coding standards, or fetching up-to-date library docs…
Handles BED-format genomic intervals (BED3 through BED12, narrowPeak/broadPeak) and the coordinate-system substrate the whole interval category rests on, with bedtools (CLI) and…
Generate AI videos with Google Veo, Seedance, Wan, Grok and 40+ models via inference.sh CLI. Models: Veo 3.1, Veo 3, Seedance 1.5 Pro, Wan 2.5, Grok Imagine Video, OmniHu — from…
Create new Claude Code Skills with proper YAML frontmatter, progressive disclosure structure, and complete directory organization.
Shell history management with Atuin. Use when configuring shell history, setting up history sync, searching command history, importing history from other shells, troubleshooting…
Implement comprehensive testing strategies using Jest, Vitest, and Testing Library for unit tests, integration tests, and end-to-end testing with mocking, fixtures, and t — from…
Master ShellCheck static analysis configuration and usage for shell script quality. Use when setting up linting infrastructure, fixing code issues, or ensuring script por — from…
Pose-conditioned generation on RunComfy via the `runcomfy` CLI. Routes across Kling 2-6 Motion Control Pro / Standard (transfer the motion / blocking of a reference video onto a…
Runs cis-pQTL Mendelian randomization for drug-target validation using UKB-PPP (Olink), deCODE (SomaScan), Fenland, INTERVAL, ARIC, and FinnGen-PPP proteomes plus colocal — from…
Optimize application performance for speed, efficiency, and scalability. Use when improving page load times, reducing bundle size, optimizing database queries, or fixing…
Preprocess ribosome profiling data including adapter trimming, size selection, rRNA removal, and alignment.
Detect syntenic blocks and structural rearrangements between genomes using MCScanX (Wang 2012), JCVI/MCScan (Tang 2008 Python), GENESPACE (Lovell 2022) for orthology-anch — from…
Use when exporting existing Azure resources to Terraform using aztfexport. Triggers on aztfexport, Azure import to Terraform, export Azure resource, bring Azure under Terraform…
Unsupervised clustering and cell-type identification for high-dimensional flow, spectral, and mass cytometry - FlowSOM, PhenoGraph, FlowSOM-via-CATALYST, with UMAP/tSNE f — from…
Tests whether two genomic interval sets overlap (colocalize) more than expected by chance using a permutation test against a structured-genome null model.
Build sequence logos from aligned DNA, RNA, or protein motifs using ggseqlogo (R), Logomaker (Python), or WebLogo with explicit bits vs probability encoding, background-frequency…
Systematic architectural thinking that emphasizes irreplaceable human capabilities. Use when designing system architecture, making technology decisions, navigating constraints, or…
Systematic strategic planning framework for philosophy and interdisciplinary academic papers targeting preprint platforms (PhilArchive, arXiv, PhilSci-Archive).
Myeloproliferative neoplasm (MPN) research expertise including JAK2/CALR/MPL mutations, myelofibrosis, polycythemia vera, essential thrombocythemia.
When the user wants to design, optimize, or audit masonry (Pinterest-style) layouts for content display.
Relight a still image — change the lighting setup, color temperature, direction, or mood — on RunComfy via the `runcomfy` CLI.
Implement Stripe payment processing for robust, PCI-compliant payment flows including checkout, subscriptions, and webhooks.
Detect A/B compartments from Hi-C data using cooltools and eigenvector decomposition. Identify active (A) and inactive (B) chromatin compartments from contact matrices.
When the user wants to add, optimize, or audit breadcrumb navigation. Also use when the user mentions "breadcrumbs," "breadcrumb trail," "breadcrumb nav," "breadcrumb links,"…
Use when creating new skills, documenting workflows, or standardizing processes into reusable skill definitions.
Next.js development tooling via MCP. Inspect routes, components, build info, and debug Next.js apps. Use when working on Next.js applications, debugging routing, or inspe — from…
Use when creating new skills, editing existing skills, or verifying skills work before deployment - applies TDD to process documentation by testing with subagents before — from…
Generate variant statistics, sample concordance, and quality metrics using bcftools stats and gtcheck.
Detect and adjust for horizontal pleiotropy in two-sample Mendelian randomization by distinguishing uncorrelated (UHP) from correlated (CHP) pleiotropy and choosing among Egger,…
Read, write, and create single-cell data objects using Seurat (R) and Scanpy (Python). Use for loading 10X Genomics data, importing/exporting h5ad and RDS files, creating — from…
Quick-reference sheet for OmicVerse tutorials spanning MOFA, GLUE pairing, SIMBA integration, TOSICA transfer, and StaVIA cartography.
Validate Ribo-seq data quality by checking 3-nucleotide periodicity and calculating P-site offsets. Use when assessing library quality or determining read offsets for dow — from…
Plot per-gene mutation distributions on a protein-domain map (lollipop / needle plots) showing mutation position, recurrence count, and variant classification with maftools,…
Calculate alignment statistics including sequence identity, conservation scores, substitution matrices, and similarity metrics.
Infer developmental trajectories and pseudotime from single-cell RNA-seq data using Monocle3, Slingshot, and scVelo for RNA velocity analysis.
Master prompt engineering for AI models: LLMs, image generators, video models. Techniques: chain-of-thought, few-shot, system prompts, negative prompts.
Senior GDPR/DSGVO expert and internal/external auditor for data protection compliance. Provides EU GDPR and German DSGVO expertise, privacy impact assessments, data prote — from…
Guide for Grafana Pyroscope continuous profiling. Use for Kubernetes Helm deployment, Go/Java/Python/.NET/Ruby/Node.js profiling, storage backends, trace-to-profile linking, and…
Picks random winners from lists, spreadsheets, or Google Sheets for giveaways, raffles, and contests. Ensures fair, unbiased selection with transparency. — from bg-szy/TOP-SKILLS
Generate user-friendly release notes from git commits. Use this when preparing releases, writing changelogs, or summarizing development progress.
Unified Python interface to 40+ bioinformatics services. Use when querying multiple databases (UniProt, KEGG, ChEMBL, Reactome) in a single workflow with consistent API — from…
Run omicverse's CellPhoneDB v5 wrapper on annotated single-cell data to infer ligand-receptor networks and produce CellChat-style visualisations.
Implement comprehensive evaluation strategies for LLM applications using automated metrics, human feedback, and benchmarking.
Analyze BCR repertoires for somatic hypermutation, clonal lineages, and B cell phylogenetics using the Immcantation framework.
Production-ready phylogenetics and sequence analysis skill for alignment processing, tree analysis, and evolutionary metrics.