Algorithmic philosophies are computational aesthetic movements that are then expressed through code. Output .md files (philosophy), .html files (interactive viewer), and — from…
Create structured incident response runbooks with step-by-step procedures, escalation paths, and recovery actions.
Call SNPs and indels from aligned reads using bcftools mpileup and call. Use when detecting variants from BAM files or generating VCF from alignments. — from bg-szy/TOP-SKILLS
Master REST and GraphQL API design principles to build intuitive, scalable, and maintainable APIs that delight developers.
Query the ClinPGx API for pharmacogenomic gene-drug data, clinical annotations, CPIC guidelines, and FDA drug labels
Schedule alarms and countdown timers in iOS apps using AlarmKit. Use when implementing alarm functionality, timer features, AlarmKit integration, snooze/stop controls, Dynamic…
KEGG pathway and module enrichment analysis using clusterProfiler enrichKEGG and enrichMKEGG. Use when identifying metabolic and signaling pathways over-represented in a — from…
Use when completing tasks, implementing major features, or before merging to verify work meets requirements — from bg-szy/TOP-SKILLS
Query myvariant.info API for aggregated variant annotations from multiple databases (ClinVar, gnomAD, dbSNP, COSMIC, etc.) in a single request.
Comprehensive code review skill for TypeScript, JavaScript, Python, Swift, Kotlin, Go. Includes automated code analysis, best practice checking, security scanning, and re — from…
Presentation creation, editing, and analysis. When Claude needs to work with presentations (.pptx files) for: (1) Creating new presentations, (2) Modifying or editing con — from…
End-to-end DNA sequencing workflow from FASTQ files to variant calls. Covers QC, alignment with BWA, BAM processing, and variant calling with bcftools or GATK HaplotypeCa — from…
Web browser game development principles. Framework selection, WebGPU, optimization, PWA. — from bg-szy/TOP-SKILLS
Export any bioinformatics analysis as a reproducible bundle with Conda environment, Singularity container definition, and Nextflow pipeline.
Marker gene-based taxonomic profiling using MetaPhlAn 4. Provides accurate species-level relative abundances using clade-specific markers.
When the user wants to create, optimize, or structure Privacy Policy page. Also use when the user mentions "privacy policy," "privacy page," "data protection," "GDPR compliance,"…
Design pegRNAs for prime editing using PrimeDesign algorithms. Generate spacer, PBS, and RT template sequences for precise genomic modifications without double-strand breaks.
Quality control and normalization for metabolomics data. Covers QC-based correction, batch effect removal, and data transformation methods.
Master advanced prompt engineering techniques to maximize LLM performance, reliability, and controllability in production.
Generate text-to-video with Wan 2.7 (Wan-AI's flagship motion model) on RunComfy. Documents Wan 2.7's strengths (multi-reference conditioning, audio-driven lip-sync via ` — from…
Use when creating new skills, documenting workflows, or standardizing processes into reusable skill definitions.
When the user wants to create, optimize, or audit media kit or press page. Also use when the user mentions "media kit," "press kit," "press page," "press resources," "brand…
Integrate and analyze multiple omics datasets (transcriptomics, proteomics, epigenomics, genomics, metabolomics) for systems biology and precision medicine.
Next.js 16.2.4 with TypeScript — App Router, Server Components, use cache directive, Turbopack dev, Server Actions, ISR, SSR, SSG, MCP devtools, metadata API, route handlers,…
Implement comprehensive testing strategies with pytest, fixtures, mocking, and test-driven development.
When the user wants to add, optimize, or audit breadcrumb navigation. Also use when the user mentions "breadcrumbs," "breadcrumb trail," "breadcrumb nav," "breadcrumb links,"…
Suite of tools for creating elaborate, multi-component claude.ai HTML artifacts using modern frontend web technologies (React, Tailwind CSS, shadcn/ui).
Writes and reviews structured Lean 4 proofs and designs Lean libraries following Mathlib conventions.
Orchestrates an end-to-end MeRIP-seq / m6A-seq analysis from raw FASTQ to differential m6A peak calls and metagene plots, chaining fastp adapter trimming, STAR splice-aware genome…
Production-ready patterns and best practices for MCP servers - architecture, security, performance, and maintenance — from bg-szy/TOP-SKILLS
Standardizes molecular structures using ChEMBL chembl_structure_pipeline and RDKit rdMolStandardize covering sanitization, salt/solvent stripping, neutralization, tautome — from…
Presentation creation, editing, and analysis. When Claude needs to work with presentations (.pptx files) for: (1) Creating new presentations, (2) Modifying or editing con — from…
Design homology-directed repair donor templates for CRISPR knock-ins using primer3-py. Create ssODN, dsDNA, or plasmid templates with optimized homology arms.
Design and implement one-click post-purchase upsells and downsells that raise average order value without hurting the main conversion rate.
Statistical analysis for metabolomics data. Covers univariate testing, multivariate methods (PCA, PLS-DA), and biomarker discovery.
Analyzes time-series and longitudinal RNA-seq for differential expression and trajectory structure. Covers DESeq2 LRT with reduced models, time as factor vs continuous vs natural…
Guide users through a structured workflow for co-authoring documentation. Use when user wants to write documentation, proposals, technical specs, decision docs, or simila — from…
Build OncoPrint and co-mutation matrix plots from somatic-variant cohorts using ComplexHeatmap, maftools, and comut.py with alteration-type stacking, sample ordering by mutational…
Review the changes since a fixed point (commit, branch, tag, or merge-base) along two axes — Standards (does the code follow this repo's documented coding standards?) and — from…
Context tracking and decision logging patterns for intentional memory management in Claude Code Waypoint Plugin.
Comprehensive SecOps skill for application security, vulnerability management, compliance, and secure development practices.
Predicts ADMET properties using ADMETlab 3.0 (119 endpoints with uncertainty), ADMET-AI, DeepChem MolNet, and chemprop D-MPNN with explicit handling of OECD QSAR principles,…
Write, optimize, and debug T-SQL queries for Microsoft SQL Server. Covers CTEs, window functions, PIVOT, MERGE, APPLY operators, execution plan analysis, indexing strategies, and…
Browser automation for AI agents via inference.sh. Navigate web pages, interact with elements using @e refs, take screenshots, record video.
Create a concise plan. Use when a user explicitly asks for a plan related to a coding task. — from bg-szy/TOP-SKILLS
Expert guide on prompt engineering patterns, best practices, and optimization techniques. Use when user wants to improve prompts, learn prompting strategies, or debug age — from…
Upload approved local HTML, markdown, or image assets to a Stitch project using direct MCP for small DESIGN.md files or the bundled API script for larger files.
Use when about to claim work is complete, fixed, or passing, before committing or creating PRs - requires running verification commands and confirming output before makin — from…
End-to-end drug discovery platform combining ChEMBL compounds, DrugBank, targets, and FDA labels. Natural language powered by Valyu.
Master on-call shift handoffs with context transfer, escalation procedures, and documentation. Use when transitioning on-call responsibilities, documenting shift summaries, or…
Integrate Firebase AI Logic (Gemini in Firebase) for intelligent app features. Use when adding AI capabilities to Firebase apps, implementing generative AI features, or setting up…
Compare cell-type composition and spatial features across conditions in IMC/MIBI cohorts with the patient as the experimental unit, covering pseudoreplication, per-patient…
Graph Neural Networks (PyG). Node/graph classification, link prediction, GCN, GAT, GraphSAGE, heterogeneous graphs, molecular property prediction, for geometric deep lear — from…
Selects informative features for biomarker discovery using Boruta all-relevant selection, mRMR minimum redundancy, and LASSO regularization.
Preprocessing and harmonization of multi-omics data before integration. Covers normalization, batch correction, feature alignment, and missing value handling across data — from…
Automate Twitter/X with posting, engagement, and user management via inference.sh CLI. Apps: x/post-tweet, x/post-create (with media), x/post-like, x/post-retweet, x/dm-s — from…
Execute Python code in a safe sandboxed environment via [inference.sh](https://inference.sh). Pre-installed: NumPy, Pandas, Matplotlib, requests, BeautifulSoup, Selenium — from…
Taxonomic classification of ASVs using reference databases like SILVA, GTDB, or UNITE. Covers naive Bayes classifiers (DADA2, IDTAXA) and exact matching approaches.
Analyzes single-cell pooled CRISPR screens (Perturb-seq, CROP-seq, Perturb-CITE-seq, ECCITE-seq, multiome) where each cell carries an sgRNA and a scRNA-seq / surface-protein /…
Run 250+ AI apps via inference.sh CLI - image generation, video creation, LLMs, search, 3D, Twitter automation.