Use when implementation is complete, all tests pass, and you need to decide how to integrate the work - guides completion of development work by presenting structured opt — from…
Comprehensive QA and testing skill for quality assurance, test automation, and testing strategies for ReactJS, NextJS, NodeJS applications.
Transfers gene annotations between genome assemblies via coordinate liftover (UCSC liftOver, CrossMap for same-species version updates) or feature/sequence projection (Liftoff for…
Render videos from React/Remotion component code via inference.sh. Pass TSX code, get MP4. Supports all Remotion APIs: useCurrentFrame, useVideoConfig, spring, interpolat — from…
Bayesian modeling with PyMC. Build hierarchical models, MCMC (NUTS), variational inference, LOO/WAIC comparison, posterior checks, for probabilistic programming and infer — from…
Quality metrics for IMC data including signal-to-noise, channel correlation, tissue integrity, and acquisition QC.
Comprehensive backend development guide for Node.js/Express/TypeScript microservices. Use when creating routes, controllers, services, repositories, middleware, or workin — from…
Analyzes time-to-event data using Kaplan-Meier curves, log-rank tests, and Cox proportional hazards regression with lifelines.
Detects and removes infostealer malware (credential stealers, data exfiltrators) via full-system file search, cryptographic hashing, and public threat-intelligence cross-checks…
Merge, concatenate, sort, intersect, and subset VCF files using bcftools. Use when combining variant files, comparing call sets, or restructuring VCF data. — from bg-szy/TOP-SKILLS
Processes eDNA metabarcoding from raw paired-end reads to species tables, navigating ASV (DADA2, UNOISE3) vs OTU (swarm v2) decision (Callahan 2017 vs Schloss multi-copy-16S…
Comprehensive CRISPR screen analysis for functional genomics. Analyze pooled or arrayed CRISPR screens (knockout, activation, interference) to identify essential genes, synthetic…
De novo motif discovery and known motif enrichment analysis using HOMER and MEME-ChIP. Identify transcription factor binding motifs in ChIP-seq, ATAC-seq, or other genomi — from…
App Store and Google Play screenshot creation with exact platform specs. Covers iOS/Android dimensions, gallery ordering, device mockups, and preview videos.
Integrate multiple scRNA-seq samples/batches using Harmony, scVI, Seurat anchors, and fastMNN. Remove technical variation while preserving biological differences.
Create professional research posters in LaTeX using beamerposter, tikzposter, or baposter. Support for conference presentations, academic posters, and scientific communic — from…
Implement Command Query Responsibility Segregation for scalable architectures. Use when separating read and write models, optimizing query performance, or building event- — from…
Build whole-genome alignments using Progressive Cactus (Armstrong 2020 reference-free clade-level WGA), Minigraph-Cactus (Hickey 2024 pangenome-aware), LASTZ chain/net (U — from…
Use when the user asks for Content Repurposing from supplied source materials. Trigger language: content repurposing; video repurposing; webinar repurposing; turn recordings into…
When the user wants to promote via forums, communities, or invite users to join a community. Also use when the user mentions "forum promotion," "Indie Hacker," "Hacker News,"…
Use when Codex, Hermes, OpenClaw, Claude Code, Cowork, or another AI agent needs to plan, review, implement, audit, or improve email work focused on behavioral triggers — from…
Use when the user asks for Sales Onboarding from supplied source materials. Trigger language: sales onboarding; sales onboarding program; new sales rep ramp.
Analyzes meeting transcripts and recordings to uncover behavioral patterns, communication insights, and actionable feedback.
Comprehensive drug-drug interaction (DDI) prediction and risk assessment. Analyzes interaction mechanisms (CYP450, transporters, pharmacodynamic), severity classification,…
Patterns and techniques for analyzing brownfield codebases. Use when onboarding to unfamiliar code, preparing for refactoring, conducting architecture reviews, or identifying…
Perform differential expression analysis using edgeR in R/Bioconductor. Use for analyzing RNA-seq count data with the quasi-likelihood F-test framework, creating DGEList — from…
Tests whether two genomic interval sets overlap (colocalize) more than expected by chance using a permutation test against a structured-genome null model.
Four-phase debugging methodology with root cause analysis. Use when investigating bugs, fixing test failures, or troubleshooting unexpected behavior.
Create scientific conference posters as native, editable .pptx files using python-pptx. Handles A0/A1 layouts, section placement, figure insertion, and academic color schemes.
Infer cell-cell communication networks from scRNA-seq data using CellChat, NicheNet, and LIANA for ligand-receptor interaction analysis.
Master advanced AgentDB features including QUIC synchronization, multi-database management, custom distance metrics, hybrid search, and distributed systems integration.
AI voice generation, text-to-speech, and voice synthesis via inference.sh CLI. Models: Kokoro TTS, DIA, Chatterbox, Higgs, VibeVoice for natural speech.
When the user wants to create, optimize, or audit resources page or content hub. Also use when the user mentions "resources page," "resource center," "content hub," "learning…
Parallel BMAD workflow orchestration using git worktrees and tmux. USE WHEN BMAD parallel, orchestrate sprint, run stories in parallel, worktree orchestration, sprint…
Launch tokens on Base blockchain via the OpenServ Launch API. Creates ERC-20 tokens with Aerodrome concentrated liquidity pools.
Annotate copy number variant segments with overlapping genes, dosage-sensitivity scores, cancer driver databases, population frequencies, and clinical-variant content.
Perform comprehensive audit of interface quality across accessibility, performance, theming, and responsive design.
Manage Supabase projects, databases, migrations, Edge Functions, and storage using the `supabase` CLI.
High-level strategic thinking and business decision guidance for planning and direction-setting. Use when: making strategic decisions, evaluating business options, setting…
When the user wants to plan integrated marketing, coordinate channels, or clarify program vs channel vs campaign.
Review p11 document comments and replies, then post useful replies to visible threads that ask questions, are unclear, are indecisive, or need input.
Estimate cell type composition in spatial transcriptomics spots using reference-based deconvolution. Use cell2location, RCTD, SPOTlight, or Tangram to infer cell type pro — from…
Cowork-style sweep of a folder of receipts, statements, and expense exports -- categorizes every transaction, matches receipts to statement lines, flags policy violations and…
\"Batteries-included agent component for React/Next.js from ui.inference.sh. One component with runtime, tools, streaming, approvals, and widgets built in.
Generate AI images with GPT-Image-2, FLUX, Gemini, Grok, Seedream, Reve and 50+ models via inference.sh CLI.
Build genome-browser-style multi-track figures with pyGenomeTracks (config-driven), Gviz (R), and IGV batch screenshotting.
Compute evolutionary distances and build phylogenetic trees using Biopython Bio.Phylo.TreeConstruction.
Use when exporting existing Azure resources to Terraform using aztfexport. Triggers on aztfexport, Azure import to Terraform, export Azure resource, bring Azure under Terraform…
Create and manage production Grafana dashboards for real-time visualization of system and application metrics.
Expert at Playwright E2E tests, Vitest unit tests, Storybook interaction tests. Use when writing tests, debugging test failures, or improving test coverage.
Lip-sync a face to a specific audio track on RunComfy via the `runcomfy` CLI. Routes across ByteDance OmniHuman (audio-driven full-body avatar from a portrait + audio), S — from…
Guide for creating high-quality MCP (Model Context Protocol) servers that enable LLMs to interact with external services through well-designed tools.
Generate and edit images with Alibaba Qwen-Image-2.0 models via inference.sh CLI. Models: Qwen-Image-2.0 (fast), Qwen-Image-2.0-Pro (professional text rendering).
Extract content from specific URLs using Tavily's extraction API. Returns clean markdown/text from web pages.
Calculate portfolio risk metrics including VaR, CVaR, Sharpe, Sortino, and drawdown analysis. Use when measuring portfolio risk, implementing risk limits, or building ris — from…
Generate text-to-video with HappyHorse 1.0 on RunComfy. Documents HappyHorse 1.0's strengths (#1 on Artificial Analysis Video Arena, native 1080p with in-pass synchronize — from…
Multi-Omics Factor Analysis (MOFA2) for unsupervised integration of multiple data modalities. Identifies shared and view-specific sources of variation.
End-to-end 16S amplicon workflow from FASTQ reads to differential abundance. Orchestrates DADA2 ASV inference, taxonomy assignment, diversity analysis, and compositional — from…
Toolkit for interacting with and testing local web applications using Playwright. Supports verifying frontend functionality, debugging UI behavior, capturing browser scre — from…
Generate AI videos on RunComfy via the `runcomfy` CLI — a smart router across the full video-model catalog: HappyHorse 1.0 (Arena #1, native in-pass audio), Wan-AI Wan 2- — from…