Build forest plots (HR, OR, RR, beta-coefficient summaries with CIs) and funnel plots (meta-analysis publication-bias diagnostics) using forestplot, metafor, ggforest, and…
Retrieves protein structure data from RCSB PDB, PDBe, and AlphaFold with protein disambiguation, quality assessment, and comprehensive structural profiles.
Strategic product leadership toolkit for Head of Product including OKR cascade generation, market analysis, vision setting, and team scaling.
Design grassroots-first campaigns for organizations facing spending disadvantages against well-funded competitors.
Analyzes cfDNA fragment size distributions and fragmentomics features using FinaleToolkit or Griffin.
Schedule alarms and countdown timers in iOS apps using AlarmKit. Use when implementing alarm functionality, timer features, AlarmKit integration, snooze/stop controls, Dynamic…
Reactome pathway enrichment using ReactomePA package. Use when analyzing gene lists against Reactome's curated peer-reviewed pathway database.
Assign pathogen lineages and track variants using Nextclade and pangolin for viral surveillance. Monitor variant prevalence and identify emerging variants of concern.
Single-cell ATAC-seq analysis with Signac (R/Seurat) and ArchR. Process 10X Genomics scATAC data, perform QC, dimensionality reduction, clustering, peak calling, and moti — from…
Construct time-scaled phylogenies and infer evolutionary dynamics using TreeTime and BEAST2 for outbreak analysis.
When the user wants to design, optimize, or audit website footers. Also use when the user mentions "footer," "page footer," "site footer," "footer links," "footer navigation,"…
Detect and remove doublets from flow and mass cytometry data. Covers FSC/SSC gating and computational doublet detection methods.
When the user wants to create, optimize, or audit an affiliate, sponsor, or paid partnership disclosure page.
Comprehensive backend development guide for Supabase Edge Functions + PostgreSQL. Use when working with Supabase (database, auth, storage, realtime), Edge Functions, PostgreSQL,…
Tactical user interface design guide for fixing layouts, selecting colors and fonts, and creating professional UIs.
KEGG pathway and module enrichment analysis using clusterProfiler enrichKEGG and enrichMKEGG. Use when identifying metabolic and signaling pathways over-represented in a — from…
Guide users through a structured workflow for co-authoring documentation. Use when user wants to write documentation, proposals, technical specs, decision docs, or simila — from…
Strategic clinical trial design feasibility assessment using ToolUniverse. Evaluates patient population sizing, biomarker prevalence, endpoint selection, comparator analysis,…
Infer orthologous genes and gene families across species using OrthoFinder3 (HOG-based phylogenetic orthology), SonicParanoid2, Broccoli, ProteinOrtho, OMA / FastOMA hier — from…
Quality control metrics for ATAC-seq data including fragment size distribution, TSS enrichment, FRiP, and library complexity.
Git branching strategy expertise with flow-aware automation. Auto-invokes when branching strategies (gitflow, github flow, trunk-based), branch creation, branch naming, merging…
Analyze PacBio Iso-Seq data for full-length isoform discovery and quantification. Use when characterizing transcript diversity or identifying novel splice variants.
When the user wants to create, optimize, or structure Privacy Policy page. Also use when the user mentions "privacy policy," "privacy page," "data protection," "GDPR compliance,"…
Design a PostgreSQL-specific schema. Covers best-practices, data types, indexing, constraints, performance patterns, and advanced features — from bg-szy/TOP-SKILLS
Map tasks to specialist agents. Use when choosing which agent for a job, comparing agent capabilities, or routing to React/Next.js/Playwright/docs/code-quality experts.
Data visualization with chart selection, color theory, and annotation best practices. Covers chart types (bar, line, scatter, heatmap), axes rules, and storytelling with data.
PLINK file formats, format conversion, and quality control filtering for population genetics. Convert between VCF, BED/BIM/FAM, and PED/MAP formats, apply MAF, genotyping — from…
Invoke external AI CLIs via native Task agents (Claude, Codex, Gemini, Cursor). Primary mode for multi-provider orchestration with fork-terminal fallback for auth.
Spillover compensation and data transformation for flow cytometry. Covers compensation matrix calculation, application, and biexponential/arcsinh transforms.
Creative research ideation and exploration. Use for open-ended brainstorming sessions, exploring interdisciplinary connections, challenging assumptions, or identifying re — from…
World-class ML engineering skill for productionizing ML models, MLOps, and building scalable ML systems.
NGS analysis toolkit. BAM to bigWig conversion, QC (correlation, PCA, fingerprints), heatmaps/profiles (TSS, peaks), for ChIP-seq, RNA-seq, ATAC-seq visualization.
Handle paired-end FASTQ files (R1/R2) using Biopython. Use when working with Illumina paired reads, synchronizing pairs, interleaving/deinterleaving, or filtering paired — from…
Assembles haplotype-resolved diploid and telomere-to-telomere (T2T) genomes from PacBio HiFi reads with hifiasm (HiFi-only, Hi-C, or trio phasing) and verkko (HiFi + ultralong ONT…
Analyze PacBio Iso-Seq data for full-length isoform discovery and quantification. Use when characterizing transcript diversity or identifying novel splice variants.
\"Batteries-included agent component for React/Next.js from ui.inference.sh. One component with runtime, tools, streaming, approvals, and widgets built in.
Product marketing, positioning, GTM strategy, and competitive intelligence. Includes ICP definition, April Dunford positioning methodology, launch playbooks, competitive — from…
Phase genotypes into haplotypes using Beagle or SHAPEIT. Resolves which alleles are inherited together on each chromosome.
Browser automation for AI agents via inference.sh. Navigate web pages, interact with elements using @e refs, take screenshots, record video.
Build GitLab CI/CD pipelines with multi-stage workflows, caching, and distributed runners for scalable automation.
Performs proximity operations on genomic intervals with bedtools (closest, window, flank, slop) and pybedtools - nearest-feature queries with signed/strand-aware distance,…
Differential binding analysis using DiffBind. Compare ChIP-seq peaks between conditions with statistical rigor. Requires replicate samples.
Aligns sample metadata with count matrices and constructs design matrices for downstream DE, handling the alphabetical-reference-level trap (relevel BEFORE DESeq), LRT…
When the user wants to improve E-E-A-T, add trust signals, or optimize for expertise and authority. Also use when the user mentions "E-E-A-T," "E-E-A-T signals," "experience…
Edit images with Flux 1 Kontext Pro (Black Forest Labs' precise local image-edit model) on RunComfy — bundled with the model's documented prompting patterns so the skill — from…
Detect antimicrobial resistance genes using AMRFinderPlus, ResFinder, and CARD. Screen isolates and metagenomes for resistance determinants.
Estimate SNP heritability and partition it across functional annotations, cell types, and loci from GWAS summary statistics or individual-level genotypes.
Access and analyze AlphaFold protein structure predictions. Use when predicted structures are needed for proteins without experimental structures, or for confidence score — from…
Automate Twitter/X with posting, engagement, and user management via inference.sh CLI. Apps: x/post-tweet, x/post-create (with media), x/post-like, x/post-retweet, x/dm-s — from…
Gene Set Enrichment Analysis using clusterProfiler gseGO and gseKEGG. Use when analyzing ranked gene lists to find coordinated expression changes in gene sets without arb — from…
Mask-driven image inpainting on RunComfy via the `runcomfy` CLI. Routes to Tongyi MAI Z-Image Turbo Inpainting (the dedicated inpainting endpoint with mask, strength, and…
Analyze population structure using PCA and admixture analysis with PLINK and ADMIXTURE. Identify population clusters, assess ancestry proportions, visualize genetic struc — from…
MUST be used for Vue.js tasks. Strongly recommends Composition API with `<script setup>` and TypeScript as the standard approach. Covers Vue 3, SSR, Volar, vue-tsc.
Build read models and projections from event streams. Use when implementing CQRS read sides, building materialized views, or optimizing query performance in event-sourced — from…
GitHub Pull Request作成スキル - 変更内容の自動サマリー、PR説明文生成、GitHub PRの作成を行います。git diffでの変更分析、コミットメッセージ取得、変更ファイル分類を行い、高品質なPR説明文を自動生成します。qa-check実行済みであることを前提とし、リモートへのプッシュとgh CLIによるPR作成を実行します。
Find bugs, security vulnerabilities, and code quality issues in local branch changes. Use when asked to review changes, find bugs, security review, or audit code on the c — from…
Guide for creating Claude Code skills following Anthropic's official best practices. Use when user wants to create a new skill, build a skill, write SKILL.md, or needs sk — from…
Video outpainting on RunComfy via the `runcomfy` CLI — extend the spatial canvas of a video, change aspect ratio (9:16 vertical to 16:9 horizontal or vice versa), add environment…
Detects somatic mutations in circulating tumor DNA using variant callers optimized for low allele fractions with UMI-based error suppression.
Designs and ranks guide RNAs (sgRNAs) for CRISPR-Cas9/Cas12a gene knockout by scanning a target for PAM sites (NGG SpCas9, NNGRRT SaCas9, TTTV Cas12a, NG SpCas9-NG, near-PAMless…