Implement comprehensive testing strategies with pytest, fixtures, mocking, and test-driven development.
Master Next.js 14+ App Router with Server Components, streaming, parallel routes, and advanced data fetching.
Conduct comprehensive literature research with target disambiguation, evidence grading, and structured theme extraction.
When the user wants to run YouTube ads, set up TrueView or Bumper campaigns, or optimize video ad creative.
Use when 需要按 Alibaba Java Coding Guidelines（阿里巴巴 Java 编码规范）审查、生成或重构 Java、Spring、MyBatis、Maven、MySQL、SQL、日志、异常、安全或数据库相关代码。 — from bg-szy/TOP-SKILLS
An example skill demonstrating the basic structure. Use when user asks about examples or templates.
Orchestrate Jira workflows end-to-end. Use when building stories with approvals, transitioning items through lifecycle states, or syncing task completion with Jira.
Use when receiving code review feedback, before implementing suggestions, especially if feedback seems unclear or technically questionable - requires technical rigor and — from…
Use when analyzing binary structure, disassembling code, or decompiling functions. Deep static analysis via radare2 (r2) and Ghidra headless - function enumeration, cross — from…
Detects structural variants (deletions, insertions, inversions, duplications, translocations) from Oxford Nanopore and PacBio long-read alignments with Sniffles2, cuteSV, SVIM,…
When the user wants to create or optimize a refund or return policy page. Also use when the user mentions "refund policy," "return policy," "money-back guarantee," "returns and…
Load spatial transcriptomics data from Visium, Xenium, MERFISH, Slide-seq, and other platforms using Squidpy and SpatialData.
When the user wants to plan cold start, get first users, or launch a new product with zero traction. Also use when the user mentions "cold start," "cold start problem," "first…
Interpret genetic variants (SNPs) from GWAS studies by aggregating evidence from multiple databases (GWAS Catalog, Open Targets Genetics, ClinVar).
Map translation initiation sites, including non-AUG and alternative starts, from initiation-drug ribosome profiling (TI-seq).
Performs structure-based virtual screening using AutoDock Vina 1.2 for molecular docking. Prepares receptor PDBQT files, generates ligand conformers, defines binding site boxes,…
Project scaffolding templates for new applications. Use when creating new projects from scratch. Contains 12 templates for various tech stacks. — from bg-szy/TOP-SKILLS
Create new skills, modify and improve existing skills, and measure skill performance. Use when users want to create a skill from scratch, edit, or optimize an existing sk — from…
Preprocessing and harmonization of multi-omics data before integration. Covers normalization, batch correction, feature alignment, and missing value handling across data — from…
GitHub operations via gh CLI. Use when user mentions: PR, pull request, github issue, workflow, actions, gh, or when git remote shows github.com.
Annotate VCF variants with VEP, ClinVar, gnomAD frequencies, and ancestry-aware context. Generates prioritised variant reports.
Predict peptide-MHC class I and II binding affinity using MHCflurry and NetMHCpan neural network models. Identify potential T-cell epitopes from protein sequences.
Perform comprehensive gene enrichment and pathway analysis using gseapy (ORA and GSEA), PANTHER, STRING, Reactome, and 40+ ToolUniverse tools.
Creates new Claude Code skills following best practices. Guides through skill structure, naming, descriptions, and progressive disclosure.
Analyze single-cell TCR and BCR data integrated with gene expression using scirpy. Use when working with 10x Genomics VDJ data alongside scRNA-seq or when integrating imm — from…
Render videos from React/Remotion component code via inference.sh. Pass TSX code, get MP4. Supports all Remotion APIs: useCurrentFrame, useVideoConfig, spring, interpolat — from…
Web search and content extraction with Tavily and Exa via inference.sh CLI. Apps: Tavily Search, Tavily Extract, Exa Search, Exa Answer, Exa Extract.
Creating algorithmic art using p5.js with seeded randomness and interactive parameter exploration. Use this when users request creating art using code, generative art, al — from…
Expert patterns for Neon serverless Postgres, branching, connection pooling, and Prisma/Drizzle integration Use when: neon database, serverless postgres, database branchi — from…
Implement the minimal code needed to make failing tests pass in the TDD green phase. — from bg-szy/TOP-SKILLS
Reusable plotting functions for common omics visualizations. Custom ggplot2/matplotlib implementations of volcano, MA, PCA, enrichment dotplots, boxplots, and survival cu — from…
Visualize enrichment results using enrichplot package functions. Use when creating publication-quality figures from clusterProfiler results.
Extract nucleosome positions from ATAC-seq data using NucleoATAC, ATACseqQC, and fragment analysis. Use when analyzing chromatin organization, identifying nucleosome-free regions…
Structured guide for setting up A/B tests with mandatory gates for hypothesis, metrics, and execution readiness. — from bg-szy/TOP-SKILLS
Creates unique, production-grade frontend interfaces with exceptional design quality. Use when user asks to build web components, pages, materials, posters, or applications (e.g.,…
Visualize ChIP-seq data using deepTools, Gviz, and ChIPseeker. Create heatmaps, profile plots, and genome browser tracks.
Generate AI videos on RunComfy via the `runcomfy` CLI — a smart router across the full video-model catalog: HappyHorse 1.0 (Arena #1, native in-pass audio), Wan-AI Wan 2- — from…
Execute plan in batches with review checkpoints. Use when partner provides a complete implementation plan to execute with controlled batches and architect review between batches.
Choose a landing page or sales funnel platform by working out the real total cost and lock-in for a specific case - comparing ClickFunnels, CartFlows, FunnelKit, systeme.io,…
Generate AI music on RunComfy via the `runcomfy` CLI — a smart router across the music-model catalog.
HARD BLOCK — never use for prediction-market/Polymarket UpDown queries; route to okx-dapp-discovery when a named DApp (Polymarket/Aave/Hyperliquid/PancakeSwap/Morpho) app — from…
Generate AI music on RunComfy via the `runcomfy` CLI. Routes across the music-model catalog to ElevenLabs AI Music Generation (premium 44.1 kHz stereo vocal tracks, 5 s–5 min) and…
Search Open Targets drug-disease associations with natural language queries. Target validation powered by Valyu semantic search.
Prioritizes rare-disease variants from trio/quad WES/WGS with de novo (DeNovoGear, Triodenovo), compound-heterozygous phasing (WhatsHap), mosaic VAF tiering, phenotype-driven…
Compose multi-panel publication figures with patchwork, cowplot, gridExtra (R), or matplotlib GridSpec/subfigures (Python) including shared axes/legends/guides collection, panel…
End-to-end flow, spectral, and mass cytometry (CyTOF) pipeline from raw FCS files to differentially abundant/expressed cell populations.
Manage database schema changes with version control. Use when modifying DB schema, adding tables/columns, or setting up new projects.
BNB Chain MCP server connection and tool usage. Covers npx @bnb-chain/mcp@latest, PRIVATE_KEY and RPC, and every MCP tool — blocks, transactions, contracts, ERC20/NFT tra — from…
Taxonomic classification of ASVs using reference databases like SILVA, GTDB, or UNITE. Covers naive Bayes classifiers (DADA2, IDTAXA) and exact matching approaches.
Load, convert, and manipulate Hi-C contact matrices using cooler format. Read .cool/.mcool files, convert from .hic format, access matrix data, and export to different fo — from…
When the user wants open source strategy, OSS commercialization, or open source growth. Also use when the user mentions "open source strategy," "OSS strategy," "open source…
Guide Claude through omicverse's bulk RNA-seq DEG pipeline, from gene ID mapping and DESeq2 normalization to statistical testing, visualization, and pathway enrichment.
Analyze competitor website structures, messaging patterns, and unique features. Use when researching competition, identifying gaps, or informing content strategy.
Unsupervised clustering and cell-type identification for high-dimensional flow, spectral, and mass cytometry - FlowSOM, PhenoGraph, FlowSOM-via-CATALYST, with UMAP/tSNE f — from…
Validate Ribo-seq data quality by checking 3-nucleotide periodicity and calculating P-site offsets. Use when assessing library quality or determining read offsets for dow — from…
Polish assemblies and call variants from Oxford Nanopore data using medaka. Uses neural networks trained on specific basecaller versions.
Build evaluation frameworks for agent systems. Use when testing agent performance systematically, validating context engineering choices, or measuring improvements over t — from…
Still-to-video conversion guide: model selection, motion prompting, and camera movement. Covers Wan 2.5 i2v, Seedance, Fabric, Grok Video with when to use each.
Read a liarjs fingerprint report and attribute each failing check to the component that produced it - what the check id measures, whether the signal comes from the launch…
Generate AI videos with Google Veo, Seedance, Wan, Grok and 40+ models via inference.sh CLI. Models: Veo 3.1, Veo 3, Seedance 1.5 Pro, Wan 2.5, Grok Imagine Video, OmniHu — from…