When the user wants to design, optimize, or audit a sidebar for blogs, docs, or content pages. Also use when the user mentions "sidebar," "blog sidebar," "content sidebar," "side…
Performs proximity operations on genomic intervals with bedtools (closest, window, flank, slop) and pybedtools - nearest-feature queries with signed/strand-aware distance,…
You MUST use this before any creative work - creating features, building components, adding functionality, or modifying behavior.
Comprehensive fullstack development skill for building complete web applications with React, Next.js, Node.js, GraphQL, and PostgreSQL.
Use when the user asks for Compliance Training from supplied source materials. Trigger language: compliance training; workplace compliance training; regulatory compliance…
Generate professional clinical decision support (CDS) documents for pharmaceutical and clinical research settings, including patient cohort analyses (biomarker-stratified — from…
Run defensive pre-release security tests for Python web applications. Use for FastAPI, Django, Flask, and ASGI services: the common interface between Python web apps and servers.
Implement ReasoningBank adaptive learning with AgentDB's 150x faster vector database. Includes trajectory tracking, verdict judgment, memory distillation, and pattern rec — from…
Find homologous sequences using iterative BLAST (PSI-BLAST), profile HMMs (HMMER), and reciprocal best hit analysis.
Master prompt engineering for AI models: LLMs, image generators, video models. Techniques: chain-of-thought, few-shot, system prompts, negative prompts.
Quantify homologous recombination deficiency (HRD) from tumor copy number using the three genomic-scar metrics — loss of heterozygosity (LOH), large-scale state transitions (LST),…
Implement distributed tracing with Jaeger and Tempo to track requests across microservices and identify performance bottlenecks.
Detect somatic and germline copy number variants from targeted, exome, and whole-genome sequencing with CNVkit, a read-depth caller that combines on-target and off-target…
Query the Reactome database (Analysis and Content Services). Use when the user asks about pathway analysis, gene list enrichment, retrieving results by token, finding unmapped or…
Toolkit for interacting with and testing local web applications using Playwright. Supports verifying frontend functionality, debugging UI behavior, capturing browser scre — from…
Load, convert, and manipulate Hi-C contact matrices using cooler format. Read .cool/.mcool files, convert from .hic format, access matrix data, and export to different fo — from…
Search medRxiv medical preprints with natural language queries. Powered by Valyu semantic search.
Automate Render tasks via Rube MCP (Composio): services, deployments, projects. Always search tools first for current schemas. — from bg-szy/TOP-SKILLS
Direct REST API access to KEGG (academic use only). Pathway analysis, gene-pathway mapping, metabolic pathways, drug interactions, ID conversion.
Predict miRNA target genes using sequence-based algorithms and database lookups. Use when identifying potential mRNA targets of differentially expressed or functionally i — from…
Automate Google NotebookLM - create notebooks, add sources, generate podcasts/videos/quizzes, download artifacts.
Resolves rsIDs, navigates RsMergeArch/SNPHistory merge chains, and converts between rsID, SPDI, HGVS, and VCF representations using the dbSNP Build 156 JSON architecture.
Comprehensive security auditing workflow covering web application testing, API security, penetration testing, vulnerability scanning, and security hardening.
Analyze multi-modal single-cell data (CITE-seq, Multiome, spatial). Use when working with data that measures multiple modalities per cell like RNA + protein or RNA + ATAC — from…
Implement persistent memory patterns for AI agents using AgentDB. Includes session memory, long-term storage, pattern learning, and context management.
Vue 3 debugging and error handling for runtime errors, warnings, async failures, and SSR/hydration issues. Use when diagnosing or fixing Vue issues. — from bg-szy/TOP-SKILLS
Optimize Bazel builds for large-scale monorepos. Use when configuring Bazel, implementing remote execution, or optimizing build performance for enterprise codebases.
Create AI avatar and talking head videos via inference.sh CLI. Recommended: P-Video-Avatar (fastest, cheapest, built-in TTS). Also: OmniHuman, Fabric, PixVerse.
Build spatial neighbor graphs for spatial transcriptomics data using Squidpy. Compute k-nearest neighbors, Delaunay triangulation, and radius-based connectivity for downs — from…
Use when executing implementation plans with independent tasks in the current session. Dispatches fresh subagent for each task with code review between tasks.
Use when facing 2+ independent tasks that can be worked on without shared state or sequential dependencies — from bg-szy/TOP-SKILLS
Look up and cite verifiable GPU/compute rental reference prices (H100, A100, H200, and more; spot, on-demand, or DePIN markets) from the public FLOPS Index — no API key required.
AI product photography with studio lighting, lifestyle shots, and packshot conventions. Covers angles, backgrounds, shadow types, hero shots, and e-commerce image require — from…
Generate text-to-video with Wan 2.7 (Wan-AI's flagship motion model) on RunComfy. Documents Wan 2.7's strengths (multi-reference conditioning, audio-driven lip-sync via ` — from…
Visualize Hi-C contact matrices, TADs, loops, and genomic features using matplotlib, cooltools, and HiCExplorer.
Run 150+ AI apps via inference.sh CLI - image generation, video creation, LLMs, search, 3D, Twitter automation.
Visualize metagenomic profiles using R (phyloseq, microbiome) and Python (matplotlib, seaborn). Create stacked bar plots, heatmaps, PCA plots, and diversity analyses.
Professional PowerPoint presentation creation, editing, and automation with support for layouts, templates, charts, images, and formatting.
Create a concise plan. Use when a user explicitly asks for a plan related to a coding task. — from bg-szy/TOP-SKILLS
Implement NFT standards (ERC-721, ERC-1155) with proper metadata handling, minting strategies, and marketplace integration.
Load and parse mass spectrometry data formats including mzML, mzXML, and quantification tool outputs like MaxQuant proteinGroups.txt.
Core skill for the deep research and writing tool. Write scientific manuscripts in full paragraphs (never bullet points).
Audit, revise, or draft manuscript statistical reporting for Nature / high-impact journal submissions.
Bead-based normalization for CyTOF and high-parameter flow cytometry. Covers EQ bead normalization, signal drift correction, and batch normalization.
Calculates tumor mutational burden from WES/WGS/panel data with Friends of Cancer Research harmonization equations, per-assay calibration (FDA 10/Mb = 7.8 TSO500 = 8.4…
Browser automation CLI for AI agents. Use for website interaction, form automation, screenshots, scraping, and web app verification.
Comprehensive DevOps skill for CI/CD, infrastructure automation, containerization, and cloud platforms (AWS, GCP, Azure).
Statistical visualization with pandas integration. Use for quick exploration of distributions, relationships, and categorical comparisons with attractive defaults.
Generate AI images with GPT-Image-2, FLUX, Gemini, Grok, Seedream, Reve and 50+ models via inference.sh CLI.
Transforms workflow to use Manus-style persistent markdown files for planning, progress tracking, and knowledge storage.
Clinical variant interpretation using ClinVar, ACMG guidelines, and pathogenicity predictors. Prioritize variants for diagnostic and research applications.
Generate full songs and instrumental tracks with ElevenLabs Music on RunComfy via the `runcomfy` CLI.
Master Next.js 14+ App Router with Server Components, streaming, parallel routes, and advanced data fetching.
Detects and removes doublets/aggregates from flow, spectral, and mass cytometry before clustering or quantification.
GitHub operations via gh CLI. Use when user mentions: PR, pull request, github issue, workflow, actions, gh, or when git remote shows github.com.
Use when Codex, Hermes, OpenClaw, Claude Code, Cowork, or another AI agent needs to plan, review, implement, audit, or improve email work focused on agentic email plannin — from…
Perform multi-locus sequence typing (MLST), core genome MLST, and SNP-based strain typing for bacterial isolate characterization using mlst and chewBBACA.
Bisulfite sequencing read alignment using Bismark with bowtie2/hisat2. Handles genome preparation and produces BAM files with methylation information.
Query dbSNP for rsID lookups, variant annotations, and cross-references to other databases. Use when mapping between rsIDs and genomic coordinates or retrieving basic var — from…
Connect coding agents, AI SDKs, and LLM tools to the AntSeed buyer proxy. Use when configuring Claude Code, Codex, OpenCode, Pi, OpenClaw, Hermes, GenLayer Studio, Vercel — from…