Render videos from React/Remotion component code via inference.sh. Pass TSX code, get MP4. Supports all Remotion APIs: useCurrentFrame, useVideoConfig, spring, interpolat — from…
Gene Ontology over-representation analysis using clusterProfiler enrichGO. Use when identifying biological functions enriched in a gene list from differential expression — from…
End-to-end gene regulatory network inference pipeline from processed single-cell data to regulon discovery and perturbation simulation.
When the user wants to design, optimize, or audit grid layouts for content display. Also use when the user mentions "grid layout," "grid design," "multi-column grid," "CSS grid,"…
Algorithmic philosophies are computational aesthetic movements that are then expressed through code. Output .md files (philosophy), .html files (interactive viewer), and — from…
为 Datadata 平台编写 DQL 数据处理脚本 — 基于 Starlark 的扩展脚本语言，支持 DataFrame/Series 操作、SQL 查询、HTTP 请求等。当用户需要编写数据转换、数据清洗、数据生成或自定义数据处理逻辑时使用此 skill。
Validate Ribo-seq data quality by checking 3-nucleotide periodicity and calculating P-site offsets. Use when assessing library quality or determining read offsets for dow — from…
Classify constitutional (germline) copy number variants for clinical reporting using the 2019 ACMG/ClinGen technical standards points-based framework, with ClassifyCNV an — from…
Notion workspace management via MCP - create databases, pages, comments, and knowledge bases. Use when building Notion documentation, organizing project wikis, or managing Notion…
Comprehensive testing strategies for Guts including unit tests, integration tests, property-based testing, and fuzzing — from bg-szy/TOP-SKILLS
When the user wants to fix indexing issues from Search Console, use noindex, or implement Google Indexing API.
Generate comprehensive, developer-friendly API documentation from code, including endpoints, parameters, examples, and best practices — from bg-szy/TOP-SKILLS
Web search and content extraction with Tavily and Exa via inference.sh CLI. Apps: Tavily Search, Tavily Extract, Exa Search, Exa Answer, Exa Extract.
Use when receiving code review feedback, before implementing suggestions, especially if feedback seems unclear or technically questionable - requires technical rigor and — from…
Create and manage Starknet wallets for AI agents. Transfer tokens, check balances, manage session keys, deploy accounts, and interact with smart contracts using native Ac — from…
Activate for building or scaffolding web apps when the user is learning (e.g., todo apps, portfolios, dashboards).
Choose RouterBase model IDs and routing strategies for chat, image, video, audio, and embeddings workloads.
Expert at TSDoc comments, Storybook stories, VitePress docs, TypeDoc API generation. Use when documenting code, adding comments, creating stories, or generating API docs.
Expert speech-language pathologist specializing in AI-powered speech therapy, phoneme analysis, articulation visualization, voice disorders, fluency intervention, and ass — from…
Predict peptide-MHC class II (HLA-DR/DQ/DP) binding and presentation for CD4 T-cell epitopes with NetMHCIIpan-4.3 and MixMHC2pred-2.0.
Evaluate recommender system quality for the CSX4207 Vinyl Record Store. Use whenever you must compute or report recommender metrics (Precision@k, Recall@k, HitRate@k, MRR, MAP@k,…
Internet Court adapter for GenLayer Intelligent Contract supervision. Use to specify agent-performance rubrics, evidence schemas, decision outputs, and ERC-7710 connector — from…
Detects allele-specific transcription factor or histone modification binding from heterozygous-variant ChIP-seq using WASP (reference-bias filter; mandatory upstream), RASQUAL…
Process multiple sequence files in batch using Biopython. Use when working with many files, merging/splitting sequences, or automating file operations across directories.
Trigger when the user asks for explanations of web development concepts, code breakdowns, or learning guidance.
Automate changelog generation from commits, PRs, and releases following Keep a Changelog format. Use when setting up release workflows, generating release notes, or stand — from…
Cleans a shotgun metagenome of everything that is not the target community before profiling - host-read depletion (Hostile, bowtie2/T2T-CHM13), reagent/kitome contamination…
Create production-ready Kubernetes manifests for Deployments, Services, ConfigMaps, and Secrets following best practices and security standards.
Create distributable Python packages with proper project structure, setup.py/pyproject.toml, and publishing to PyPI.
When the user wants to promote via forums, communities, or invite users to join a community. Also use when the user mentions "forum promotion," "Indie Hacker," "Hacker News,"…
Quality control for pooled CRISPR screens. Covers library representation, read distribution, replicate correlation, and essential gene recovery.
Plugin router for 20 third-party DeFi protocols (Polymarket, Aave, Hyperliquid, PancakeSwap, Morpho, Raydium, Curve, Compound, Pendle, Lido, ether.fi, GMX, Kamino, Orca — from…
Validate alignment quality with insert size distribution, proper pairing rates, GC bias, strand balance, and other post-alignment metrics.
When the user wants to plan cold start, get first users, or launch a new product with zero traction. Also use when the user mentions "cold start," "cold start problem," "first…
Use when the user asks for Product Change Adoption Course from supplied source materials. Trigger language: product update; feature adoption; migration guide; breaking change;…
End-to-end alternative splicing analysis from FASTQ to differential splicing results for short-read bulk RNA-seq.
Build forest plots (HR, OR, RR, beta-coefficient summaries with CIs) and funnel plots (meta-analysis publication-bias diagnostics) using forestplot, metafor, ggforest, and…
Assembles genomes de novo from noisy long reads (Oxford Nanopore R9/R10/Dorado, PacBio CLR) with Flye (repeat graph), Canu (correct-trim-assemble OLC), NextDenovo, Shasta, Raven,…
Install a complete design-token theme into any project in one pass -- pulls a style from the Open Agent Stack design-styles collection (aurora-mesh, cirrus, liquid-glass,…
Searches molecular libraries for substructure matches using SMARTS patterns with explicit handling of recursive SMARTS, ring membership, aromaticity dialect, vector bindi — from…
Design guides for cytosine and adenine base editing using editing window optimization and BE-Hive outcome prediction.
Process and analyze single-cell ATAC-seq data with Signac, ArchR, SnapATAC2, or Cell Ranger ATAC. Use when handling 10X scATAC or 10X Multiome (paired RNA+ATAC) data, performing…
Generate images with Google Gemini native image models via inference.sh CLI. Models: Gemini 3 Pro Image, Gemini 2.5 Flash Image.
Generate AI videos on RunComfy via the `runcomfy` CLI — a smart router across the full video-model catalog: HappyHorse 1.0 (Arena #1, native in-pass audio), Wan-AI Wan 2- — from…
Generate or edit images using AI models (FLUX, Gemini). Use for general-purpose image generation including photos, illustrations, artwork, visual assets, concept art, and any…
Batch effect correction for CRISPR screens. Covers normalization across batches, technical replicate handling, and batch-aware analysis.
Walk through omicverse's single-cell preprocessing tutorials to QC PBMC3k data, normalise counts, detect HVGs, and run PCA/embedding pipelines on CPU, CPU–GPU mixed, or G — from…
When the user wants to create, optimize, or audit a startups, education, or special program page. Also use when the user mentions "startups program," "for startups," "education…
Single-cell ATAC-seq analysis with Signac (R/Seurat) and ArchR. Process 10X Genomics scATAC data, perform QC, dimensionality reduction, clustering, peak calling, and moti — from…
Implement proven backend architecture patterns including Clean Architecture, Hexagonal Architecture, and Domain-Driven Design.
macOS development environment setup wizard. Interactive Q&A to collect preferences, auto-detect installed software, generate customized installation plan.
Trim multiple sequence alignments using ClipKIT, trimAl, BMGE, Divvier, or HMMcleaner with mode selection guidance per downstream goal.
Access COSMIC cancer mutation database. Query somatic mutations, Cancer Gene Census, mutational signatures, gene fusions, for cancer research and precision oncology.
Use when working on Nuxt 4+ projects - provides server routes, file-based routing, middleware patterns, Nuxt-specific composables, and configuration with latest docs.
Organizational coding standards and architectural patterns. References comprehensive skills for detailed patterns. Use when making architecture decisions or implementing features.
Prepare YOUR data room for a fundraise, acquisition, or bank diligence -- builds the checklist for your deal stage, sweeps your folders for what you already have, produces a gap…
Use when encountering any bug, test failure, or unexpected behavior, before proposing fixes — from bg-szy/TOP-SKILLS
Generate pileup data for variant calling using samtools mpileup and pysam. Use when preparing data for variant calling, analyzing per-position read data, or calculating a — from…
Automatically creates user-facing changelogs from git commits by analyzing commit history, categorizing changes, and transforming technical commits into clear, customer-f — from…
Spreadsheet toolkit (.xlsx/.csv). Create/edit with formulas/formatting, analyze data, visualization, recalculate formulas, for spreadsheet processing and analysis.