Use only when the user explicitly requests strict code-cell-only output for a Jupyter or undergraduate data-science task, or when an ITX2007 assignment requires that format.
Use when medium-to-large changes need explicit requirements, technical design, and task planning before implementation, especially for multi-module work, unclear acceptance…
Master REST and GraphQL API design principles to build intuitive, scalable, and maintainable APIs that delight developers.
Edit images with Google Nano Banana 2 (image-to-image edit endpoint) on RunComfy. Documents Nano Banana Edit's strengths (preserve subject identity, swap background, loca — from…
Computes sample size and power for clinical trials including continuous, binary, and time-to-event endpoints; superiority, non-inferiority, and equivalence designs; FDA 2 — from…
Use when about to claim work is complete, fixed, or passing, before committing or creating PRs - requires running verification commands and confirming output before makin — from…
Process Hi-C read pairs using pairtools. Parse alignments, filter duplicates, classify pairs, and generate contact statistics from Hi-C sequencing data.
When the user wants to analyze backlinks, audit link profile, or identify link issues. Also use when the user mentions "backlink analysis," "backlink audit," "referring domains,"…
Improves the quality of images, especially screenshots, by enhancing resolution, sharpness, and clarity.
Use when the user asks for Sales Onboarding from supplied source materials. Trigger language: sales onboarding; sales onboarding program; new sales rep ramp.
Use when receiving code review feedback, before implementing suggestions, especially if feedback seems unclear or technically questionable - requires technical rigor and — from…
Comprehensive security auditing workflow covering web application testing, API security, penetration testing, vulnerability scanning, and security hardening.
Bulk-query Ensembl BioMart (and other BioMart instances) for cross-database ID mapping, gene/transcript/exon coordinates, and ortholog tables.
Infer large-scale copy-number alterations from tumor single-cell or single-nucleus RNA-seq to separate malignant from normal cells and call subclones, using inferCNV, copyKAT,…
Estimate cell type composition in spatial transcriptomics spots using reference-based deconvolution. Use cell2location, RCTD, SPOTlight, or Tangram to infer cell type pro — from…
JavaScript/TypeScript SDK for inference.sh - run AI apps, build agents, integrate 150+ models. Package: @inferencesh/sdk (npm install).
Generate images with Google Gemini native image models via inference.sh CLI. Models: Gemini 3 Pro Image, Gemini 2.5 Flash Image.
Calls significant loops from protein-directed and targeted 3C assays (HiChIP, PLAC-seq, Capture Hi-C/PCHi-C, ChIA-PET) where the contact background is peak-anchored and…
Use when you have a written implementation plan to execute in a separate session with review checkpoints — from bg-szy/TOP-SKILLS
Query the CELLxGENE Census (61M+ cells) programmatically. Use when you need expression data across tissues, diseases, or cell types from the largest curated single-cell a — from…
Checkpoint framework and validation rules for all agents. Ensures quality gates are passed at every stage of development.
Create detailed implementation plans with granular tasks. Use before implementing features or complex changes.
Vite 8.0.10 build tooling — HMR, fast builds, plugins, and optimized production assets. Use when configuring Vite, setting up React/Vue projects with Vite, or optimizing frontend…
Implement GDPR-compliant data handling with consent management, data subject rights, and privacy by design.
Generate and edit images with Alibaba Qwen-Image-2.0 models via inference.sh CLI. Models: Qwen-Image-2.0 (fast), Qwen-Image-2.0-Pro (professional text rendering).
When the user wants to add or optimize Twitter Card metadata for X (Twitter) link previews. Also use when the user mentions "Twitter Card," "twitter:card," "twitter:image,"…
Execute Python code in a safe sandboxed environment via [inference.sh](https://inference.sh). Pre-installed: NumPy, Pandas, Matplotlib, requests, BeautifulSoup, Selenium — from…
Build publication-quality figures in R with ggplot2 using the grammar of graphics (data + aesthetics + geometries + scales + facets + themes) with CVD-safe palettes, cairo_pdf…
When the user wants to run display, banner, or ad network campaigns. Also use when the user mentions "display ads," "banner ads," "ad network," "ad alliance," "programmatic…
Applies Anthropic's official brand colors and typography to any sort of artifact that may benefit from having Anthropic's look-and-feel.
Perform differential expression analysis of miRNAs between conditions using DESeq2 or edgeR with small RNA-specific considerations.
Call copy number variants using GATK best practices workflow. Supports both somatic (tumor-normal) and germline CNV detection from WGS or WES data.
Comprehensive spreadsheet creation, editing, and analysis with support for formulas, formatting, data analysis, and visualization.
Perform comprehensive code reviews covering security, style, performance, and best practices. Use when reviewing code changes before commit or merge, auditing existing code, or…
Use this umbrella skill when the request spans multiple Cloud Claw user-facing domains, especially launching a new AltClaw or OpenClaw VM and then managing lifecycle, log — from…
Compose multi-panel publication figures with patchwork, cowplot, gridExtra (R), or matplotlib GridSpec/subfigures (Python) including shared axes/legends/guides collection, panel…
Use when facing 2+ independent tasks that can be worked on without shared state or sequential dependencies — from bg-szy/TOP-SKILLS
Spatial analysis of cell neighborhoods and interactions in IMC data. Covers neighbor graphs, spatial statistics, and interaction testing.
Assesses the quality and completeness of a genome annotation with BUSCO (conserved single-copy ortholog recovery), OMArk (proteome completeness, consistency, and contamination),…
Query Open Targets Platform for target-disease associations, drug target discovery, tractability/safety data, genetics/omics evidence, known drugs, for therapeutic target — from…
Normalize indel representation and split multiallelic variants using bcftools norm. Use when comparing variants from different callers or preparing VCF for downstream ana — from…
Discovers, classifies, and masks repetitive elements and transposable elements with RepeatModeler2 (de novo family library), RepeatMasker (masking against a library), EDT — from…
Turborepo monorepo build system guidance. Triggers on: turbo.json, task pipelines, dependsOn, caching, remote cache, the "turbo" CLI, --filter, --affected, CI optimizatio — from…
Authentication and access control skill for Next.js 15 + Supabase applications. Use when implementing user authentication, protecting routes, managing user sessions, enforcing…
Create generative art using p5.js with seeded randomness. Use this when creating procedural art, interactive visualizations, or algorithmic designs.
Use when creating new skills, editing existing skills, or verifying skills work before deployment — from bg-szy/TOP-SKILLS
Parallel BMAD workflow orchestration using git worktrees and tmux. USE WHEN BMAD parallel, orchestrate sprint, run stories in parallel, worktree orchestration, sprint…
AI voice generation, text-to-speech, and voice synthesis via inference.sh CLI. Models: Kokoro TTS, DIA, Chatterbox, Higgs, VibeVoice for natural speech.
Comprehensive spreadsheet creation, editing, and analysis with support for formulas, formatting, data analysis, and visualization.
Infer developmental trajectories and pseudotime from single-cell RNA-seq data using Monocle3, Slingshot, and scVelo for RNA velocity analysis.
Resolves GWAS associations to candidate causal variants and credible sets via SuSiE, susie_rss, FINEMAP, CAVIAR, DAP-G, PAINTOR, PolyFun, SuSiEx, MultiSuSiE, and FOCUS.
Protein quantification from mass spectrometry data including label-free (LFQ, intensity-based), isobaric labeling (TMT, iTRAQ), and metabolic labeling (SILAC) approaches — from…
Turn a decision you can't fully answer into a questionnaire for someone else to fill in.
Implement efficient similarity search with vector databases. Use when building semantic search, implementing nearest neighbor queries, or optimizing retrieval performance — from…
Installs 425 bioinformatics skills covering sequence analysis, RNA-seq, single-cell, variant calling, metagenomics, structural biology, and 56 more categories.
Build governed incident command packets. Use when asked to standardize incident review, run severity assessment, or assemble incident communication. — from bg-szy/TOP-SKILLS
Comprehensive spreadsheet creation, editing, and analysis with support for formulas, formatting, data analysis, and visualization.
When the user wants to design, optimize, or audit grid layouts for content display. Also use when the user mentions "grid layout," "grid design," "multi-column grid," "CSS grid,"…
When the user wants to plan, implement, or optimize student and education discount programs. Also use when the user mentions "student discount," "education discount," "student…
Film and video storyboarding with shot vocabulary, continuity rules, and panel layout. Covers shot types, camera angles, movement, 180-degree rule, and annotation format — from…