Render videos from React/Remotion component code via inference.sh. Pass TSX code, get MP4. Supports all Remotion APIs: useCurrentFrame, useVideoConfig, spring, interpolat — from…
Configure Turborepo for efficient monorepo builds with local and remote caching. Use when setting up Turborepo, optimizing build pipelines, or implementing distributed ca — from…
Master effective code review practices to provide constructive feedback, catch bugs early, and foster knowledge sharing while maintaining team morale.
Query the Genome Aggregation Database (gnomAD). Use when determining the rarity or allele frequency of specific genetic variants, retrieving gene constraint metrics (pLI, LOEUF)…
Create production-ready GitHub Actions workflows for automated testing, building, and deploying applications.
Structures biological experiments so inference is valid by construction, covering Fisher's principles (randomization, replication, local control), the…
Comprehensive knowledge system for addiction recovery environments, supporting both residential and outpatient (IOP/PHP) patients.
Master the uv package manager for fast Python dependency management, virtual environments, and modern Python project workflows.
Predict CRISPR off-target sites using Cas-OFFinder and CFD scoring algorithms. Identify potential unintended cleavage sites genome-wide and assess guide specificity.
Use when the user asks for Developer Quickstart from supplied source materials. Trigger language: developer quickstart; API tutorial; SDK tutorial; first successful API call.
Upload approved local HTML, markdown, or image assets to a Stitch project using direct MCP for small DESIGN.md files or the bundled API script for larger files.
Comprehensive frontend development skill for building modern, performant web applications using ReactJS, NextJS, TypeScript, Tailwind CSS.
Validate, gap-fill, and curate genome-scale metabolic models using memote for quality scores and COBRApy for manual curation.
Run 150+ AI apps via inference.sh CLI - image generation, video creation, LLMs, search, 3D, Twitter automation.
Peptide-spectrum matching and protein identification from MS/MS data. Use when identifying peptides from tandem mass spectra.
Quality control metrics for ATAC-seq data including fragment size distribution, TSS enrichment, FRiP, and library complexity.
Build scalable design systems with Tailwind CSS, design tokens, component libraries, and responsive patterns.
WikiPathways enrichment using clusterProfiler and rWikiPathways. Use when analyzing gene lists against community-curated open-source pathways.
Balance, normalize, and transform Hi-C contact matrices using cooler and cooltools. Apply iterative correction (ICE), compute expected values, and generate observed/expec — from…
Expert at performing task X automatically. Auto-invokes when the user wants to do Y, needs help with Z, or encounters situation W. — from bg-szy/TOP-SKILLS
將提示詞和程式碼從 Claude Sonnet 4.0、Sonnet 4.5 或 Opus 4.1 遷移至 Opus 4.5。當使用者想要更新其程式碼庫、提示詞或 API 呼叫以使用 Opus 4.5 時使用。處理模型字串更新和針對已知 Opus 4.5 行為差異的提示詞調整。不會遷移 Haiku 4.5。 — from bg-szy/TOP-SKILLS
Multi-Omics Factor Analysis (MOFA2) for unsupervised integration of multiple data modalities. Identifies shared and view-specific sources of variation.
Calls HLA class I and class II alleles at 2/4/6/8-field resolution from WGS/WES/RNA-seq/long-read data using OptiType, HLA-LA, T1K, Polysolver, HLA-HD, arcasHLA, StarPhase, or…
Map N6-methyladenosine (m6A) RNA modifications at single-nucleotide resolution using miCLIP (Linder 2015), miCLIP2 + m6Aboost machine learning (Kortel 2021), GLORI (Liu 2023,…
End-to-end ChIP-seq workflow from FASTQ files to annotated peaks. Covers QC, alignment, peak calling with MACS3 (or HOMER), and peak annotation with ChIPseeker.
Query protein-protein and gene interaction databases (STRING, BioGRID, IntAct, SIGNOR, Reactome, HuRI, HuMAP, OmniPath, ConsensusPathDB, DIP).
Deep learning-based variant calling with Google DeepVariant. Provides high accuracy for germline SNPs and indels from Illumina, PacBio, and ONT data.
Process and analyze tissue images from spatial transcriptomics data using Squidpy. Extract image features, segment cells/nuclei, and compute morphological features from H — from…
Production-ready VCF processing, variant annotation, mutation analysis, and structural variant (SV/CNV) interpretation for bioinformatics questions.
Access protein metadata, function, taxonomy, and sequences across UniProtKB, UniParc, and UniRef. Use when searching for proteins, mapping identifiers, or retrieving functional…
Align long reads using minimap2 for Oxford Nanopore and PacBio data. Supports various presets for different read types and applications.
Performs logistic regression for clinical trial outcomes (binary, ordinal, multinomial) with marginal-vs-conditional estimand reporting per FDA 2023 covariate adjustment guidance,…
Calculate alignment statistics including sequence identity, conservation scores, substitution matrices, and similarity metrics.
Resolves GWAS associations to candidate causal variants and credible sets via SuSiE, susie_rss, FINEMAP, CAVIAR, DAP-G, PAINTOR, PolyFun, SuSiEx, MultiSuSiE, and FOCUS.
Queries PharmGKB / CPIC / DPWG for drug-gene interactions; calls CYP2D6/CYP2C9/CYP2C19/DPYD/TPMT/NUDT15/UGT1A1/SLCO1B1 star alleles and phenotype with PharmCAT, Cyrius (CYP2D6…
\"Chat UI building blocks for React/Next.js from ui.inference.sh. Components: container, messages, input, typing indicators, avatars.
Render videos from React/Remotion component code via inference.sh. Pass TSX code, get MP4. Supports all Remotion APIs: useCurrentFrame, useVideoConfig, spring, interpolat — from…
Detect introgression and admixture between species or populations using Dsuite (Malinsky 2021 fast D-statistics), Patterson's D / ABBA-BABA test (Green 2010; Durand 2011) — from…
Call copy number variants using GATK best practices workflow. Supports both somatic (tumor-normal) and germline CNV detection from WGS or WES data.
UI/UX design intelligence. 50 styles, 21 palettes, 50 font pairings, 20 charts, 8 stacks (React, Next.js, Vue, Svelte, SwiftUI, React Native, Flutter, Tailwind).
Multi-objective optimization framework. NSGA-II, NSGA-III, MOEA/D, Pareto fronts, constraint handling, benchmarks (ZDT, DTLZ), for engineering design and optimization pro — from…
Generate images with Alibaba Qwen-Image-2.0-Pro via inference.sh CLI. Professional text rendering, fine-grained realism, enhanced semantic adherence.
Model product UI actions from user intent questions after a meaningful outcome, completion, created resource, imported data, uploaded file, synced integration, report, deployment,…
Data-independent acquisition (DIA) proteomics analysis with DIA-NN and other tools. Use when analyzing DIA mass spectrometry data with library-free or library-based workf — from…
Apply STRIDE methodology to systematically identify threats. Use when analyzing system security, conducting threat modeling sessions, or creating security documentation.
Comprehensive document creation, editing, and analysis with support for tracked changes, comments, formatting preservation, and text extraction.
Mark and remove PCR/optical duplicates using samtools fixmate and markdup. Use when preparing alignments for variant calling or when duplicate reads would bias analysis.
Comprehensive software architecture skill for designing scalable, maintainable systems using ReactJS, NextJS, NodeJS, Express, React Native, Swift, Kotlin, Flutter, Postg — from…
Use when starting any conversation - establishes how to find and use skills, requiring Skill tool invocation before ANY response including clarifying questions — from…
Call copy number variants with the GATK best-practices workflows — the somatic CNV pipeline (CollectReadCounts, DenoiseReadCounts with tangent normalization, ModelSegments,…
Analyze PacBio Iso-Seq data for full-length isoform discovery and quantification. Use when characterizing transcript diversity or identifying novel splice variants.
Visualize spatial transcriptomics data using Squidpy and Scanpy. Create tissue plots with gene expression, clusters, and annotations overlaid on histology images.
Comprehensive drug-drug interaction (DDI) prediction and risk assessment. Analyzes interaction mechanisms (CYP450, transporters, pharmacodynamic), severity classification,…
Query Reactome REST API for pathway analysis, enrichment, gene-pathway mapping, disease pathways, molecular interactions, expression analysis, for systems biology studies — from…
Generate images with Google Nano Banana 2 (Gemini-family flash-tier text-to-image) on RunComfy — bundled with the model's documented prompting patterns so the skill gets — from…
Refresh a safe, concise map of this GCI World 2026 workspace before deeper course, assignment, or dataset work.
Bayesian modeling with PyMC. Build hierarchical models, MCMC (NUTS), variational inference, LOO/WAIC comparison, posterior checks, for probabilistic programming and infer — from…
Preprocesses cell-free DNA sequencing data including adapter trimming, alignment optimized for short fragments, and UMI-aware duplicate removal using fgbio.
When the user wants to plan integrated marketing, coordinate channels, or clarify program vs channel vs campaign.
When the user wants to design, optimize, or audit site navigation menus. Also use when the user mentions "navigation," "nav menu," "header menu," "site structure," "menu design,"…