Generate AI chat completions using GPT-4o through the verging.ai proxy API with streaming (SSE) and non-streaming response support.
Generates comprehensive drug research reports with compound disambiguation, evidence grading, and mandatory completeness sections.
Load and preprocess imaging mass cytometry (IMC) and MIBI data. Covers MCD/TIFF handling, hot pixel removal, and image normalization.
Lightweight WSI tile extraction and preprocessing. Use for basic slide processing tissue detection, tile extraction, stain normalization for H&E images.
Calculates molecular fingerprints (ECFP/Morgan, FCFP, MACCS, RDKit, AtomPair, TopologicalTorsion, Avalon, MAP4, MHFP6) and physicochemical descriptors (Lipinski, QED, TPSA,…
Analyzes meeting transcripts and recordings to uncover behavioral patterns, communication insights, and actionable feedback.
Run 150+ AI apps via inference.sh CLI - image generation, video creation, LLMs, search, 3D, Twitter automation.
Infer cis-regulatory connections (peak-to-peak co-accessibility) from scATAC-seq using Cicero, ArchR getCoAccessibility, or SCENIC+.
Comprehensive Docker containerization workflow covering multi-stage builds, docker-compose orchestration, image optimization, debugging, and production best practices.
Compute evolutionary distances and build phylogenetic trees using Biopython Bio.Phylo.TreeConstruction.
Generate and deploy a complete brand asset pack for a Next.js App Router project. Scans the project, prints what to generate with exact specs, then imports and wires everything…
Generates the storyboard sheets for a video — one image per clip, panels in a row, each panel one action.
When the user wants to create or optimize an email sequence, drip campaign, automated email flow, or lifecycle email program.
When the user wants to optimize post-signup onboarding, user activation, first-run experience, or time-to-value.
Identifies essential genes from CRISPR-Cas9 fitness screens using BAGEL2 (Kim & Hart 2021 Genome Med), a Bayesian classifier scoring per-gene Bayes Factors via log-likelihood…
Generate text-to-video with Wan 2.7 (Wan-AI's flagship motion model) on RunComfy. Documents Wan 2.7's strengths (multi-reference conditioning, audio-driven lip-sync via ` — from…
HARD BLOCK — never use for prediction-market/Polymarket UpDown queries; route to okx-dapp-discovery when a named DApp (Polymarket/Aave/Hyperliquid/PancakeSwap/Morpho) app — from…
Performs differential expression on bulk RNA-seq count data with DESeq2's negative-binomial GLM, Wald and LRT testing, apeglm/ashr/normal LFC shrinkage, independent filtering,…
Create and edit Obsidian Bases (.base files) with views, filters, formulas, and summaries. Use when working with .base files, creating database-like views of notes, or wh — from…
Orchestrates the cell-free DNA / liquid-biopsy pipeline from plasma sequencing to tumor monitoring, forking tumor-naive (screening) vs tumor-informed (MRD), and chaining — from…
Generate variant statistics, sample concordance, and quality metrics using bcftools stats and gtcheck.
Perform comprehensive gene enrichment and pathway analysis using gseapy (ORA and GSEA), PANTHER, STRING, Reactome, and 40+ ToolUniverse tools.
When the user wants to plan product distribution via marketplaces, app stores, or third-party platforms.
Analyze Perturb-seq and CROP-seq CRISPR screening data integrated with scRNA-seq. Use when identifying gene function through pooled genetic perturbations in single cells.
Mask-driven image inpainting on RunComfy via the `runcomfy` CLI. Routes to Tongyi MAI Z-Image Turbo Inpainting (the dedicated inpainting endpoint with mask, strength, and — from…
Create commit messages following Sentry conventions. Use when committing code changes, writing commit messages, or formatting git history.
Security review or audit of code, architecture, or infrastructure - Threat modeling sessions - Reviewing PRs for security implications
App Store and Google Play screenshot creation with exact platform specs. Covers iOS/Android dimensions, gallery ordering, device mockups, and preview videos.
Create, list, and apply Stitch design systems from DESIGN.md using the verified Stitch MCP design-system tools and safe upload fallbacks.
Implement comprehensive testing strategies with pytest, fixtures, mocking, and test-driven development.
Differentially methylated region (DMR) detection using methylKit tiles, bsseq BSmooth, and DMRcate. Use when identifying contiguous genomic regions with methylation diffe — from…
Metabolite identification from m/z and retention time. Covers database matching, MS/MS spectral matching, and confidence level assignment.
Differential gene expression analysis (Python DESeq2). Identify DE genes from bulk RNA-seq counts, Wald tests, FDR correction, volcano/MA plots, for RNA-seq analysis.
Use when executing implementation plans with independent tasks in the current session — from bg-szy/TOP-SKILLS
Discovers, classifies, and masks repetitive elements and transposable elements with RepeatModeler2 (de novo family library), RepeatMasker (masking against a library), EDT — from…
Calculate linkage disequilibrium statistics (r², D'), perform LD pruning for population structure analysis, identify haplotype blocks, and visualize LD patterns using PLI — from…
When the user wants to configure, audit, or optimize robots.txt. Also use when the user mentions "robots.txt," "crawler rules," "block crawlers," "AI crawlers," "GPTBot,"…
Infer transcription factor regulons from single-cell RNA-seq with pySCENIC by combining GRNBoost2 co-expression, cisTarget motif-enrichment pruning, and AUCell per-cell activity…
High-impact scientific manuscript preparation for journals like Nature, Blood, Cell. Use when writing abstracts, introductions, methods, results, discussions, or figure legends.
Analyzes time-to-event data using Kaplan-Meier curves, log-rank tests, and Cox proportional hazards regression with lifelines.
Comprehensive guide for integrating Obsidian vaults as AI-powered second brains with Claude Code. Covers MCP integration, vault manifests, self-evolving patterns, auto-linking,…
Use when building, debugging, or evaluating CloudBase PostgreSQL / CloudBase PG / PG mode apps, including Postgres schema setup, queryPgDatabase/managePgDatabase, JS SDK — from…
Guides Claude in creating well-structured SKILL.md files following best practices. Provides clear guidelines for naming, structure, and content organization to make skill — from…
Master REST and GraphQL API design principles to build intuitive, scalable, and maintainable APIs that delight developers.
When the user wants to plan, create, or market a podcast. Also use when the user mentions "podcast," "podcast strategy," "podcast SEO," "show notes," "podcast distributio — from…
Master Go 1.21+ with modern patterns, advanced concurrency, performance optimization, and production-ready microservices. — from bg-szy/TOP-SKILLS
Use when implementation is complete, all tests pass, and you need to decide how to integrate the work - guides completion of development work by presenting structured opt — from…
Suite of tools for creating elaborate, multi-component claude.ai HTML artifacts using modern frontend web technologies (React, Tailwind CSS, shadcn/ui).
Get a local business found on Google -- audit and optimize the Google Business Profile, local pack ranking factors, review velocity, NAP consistency across directories, and…
Access ClinPGx pharmacogenomics data (successor to PharmGKB). Query gene-drug interactions, CPIC guidelines, allele functions, for precision medicine and genotype-guided — from…
Preprocessing and harmonization of multi-omics data before integration. Covers normalization, batch correction, feature alignment, and missing value handling across data — from…
Perform geometric calculations on protein structures using Biopython Bio.PDB. Use when measuring distances, angles, and dihedrals, superimposing structures, calculating R — from…
Map scRNA-seq atlases onto spatial transcriptomics slides using omicverse's Single2Spatial workflow for deep-forest training, spot-level assessment, and marker visualisat — from…
Guide for creating high-quality MCP (Model Context Protocol) servers that enable LLMs to interact with external services through well-designed tools.
Manages shadcn components and projects — adding, searching, fixing, debugging, styling, and composing UI, including chat interfaces.
Audit your calendar with Cowork's calendar tools -- measure meeting load and fragmentation, identify which recurring meetings earn their slot, propose consolidations and focus…
Visualize Hi-C contact matrices, TADs, loops, and genomic features using matplotlib, cooltools, and HiCExplorer.
When the user wants to create, audit, or optimize sitemap.xml. Also use when the user mentions "sitemap," "sitemap.xml," "sitemap index," "lastmod," "changefreq," "priority," "URL…
Write competitive research proposals for NSF, NIH, DOE, DARPA, and Taiwan NSTC. Agency-specific formatting, review criteria, budget preparation, broader impacts, signific — from…
Analyzes cfDNA methylation patterns for cancer detection using cfMeDIP-seq or bisulfite sequencing with MethylDackel.