Implement adaptive learning with ReasoningBank for pattern recognition, strategy optimization, and continuous improvement.
DNAnexus cloud genomics platform. Build apps/applets, manage data (upload/download), dxpy Python SDK, run workflows, FASTQ/BAM/VCF, for genomics pipeline development and — from…
Create structured docs from scratch — PRDs, technical specs, design docs, decision records, knowledge bases.
QIIME2 command-line workflow for 16S/ITS amplicon analysis. Alternative to DADA2/phyloseq R workflow with built-in provenance tracking.
Profile functional potential of metagenomes using HUMAnN3 and similar tools. Use when obtaining pathway abundances, gene family counts, or functional annotations from met — from…
Coordinator workflow for orchestrating dockeragents through fix-review-iterate-present loop. Use when delegating any task that produces code changes.
Specialized knowledge of Bash and Zsh scripting, shell automation, command-line tools, and scripting best practices.
Guide Claude through ingesting TCGA sample sheets, expression archives, and clinical carts into omicverse, initialising survival metadata, and exporting annotated AnnData files.
Design guides for cytosine and adenine base editing using editing window optimization and BE-Hive outcome prediction.
Analyzes cfDNA fragment size distributions and fragmentomics features using FinaleToolkit or Griffin.
Identifies high-quality leads for your product or service by analyzing your business, searching for target companies, and providing actionable contact strategies.
Robusta Kubernetes observability and alert automation platform. USE WHEN installing Robusta OR configuring playbooks OR setting up notification sinks OR troubleshooting Kubernetes…
Review UI code for Web Interface Guidelines compliance. Use when asked to "review my UI", "check accessibility", "audit design", "review UX", or "check my site against be — from…
Microscopy data management platform. Access images via Python, retrieve datasets, analyze pixels, manage ROIs/annotations, batch processing, for high-content screening an — from…
Detect transcription factor binding sites through footprinting analysis in ATAC-seq data using TOBIAS.
Analyze API, schema, and contract changes; map affected consumers, assess business risk, generate an impact report, and support commit guarding with compatibility fixes.
Render videos from React/Remotion component code via inference.sh. Pass TSX code, get MP4. Supports all Remotion APIs: useCurrentFrame, useVideoConfig, spring, interpolat — from…
Design and implement one-click post-purchase upsells and downsells that raise average order value without hurting the main conversion rate.
Comprehensive computational validation of drug targets for early-stage drug discovery. Evaluates targets across 10 dimensions (disambiguation, disease association, druggability,…
Parse and write protein structure files using Biopython Bio.PDB. Use when reading PDB, mmCIF, and MMTF files, downloading structures from RCSB PDB, or writing structures — from…
Use when implementation is complete, all tests pass, and you need to decide how to integrate the work - guides completion of development work by presenting structured opt — from…
Analyzes isoform switching events and functional consequences using IsoformSwitchAnalyzeR. Predicts protein domain changes, NMD sensitivity, ORF alterations, and coding potential…
Validate alignment quality with insert size distribution, proper pairing rates, GC bias, strand balance, and other post-alignment metrics.
Use when encountering any bug, test failure, or unexpected behavior, before proposing fixes — from bg-szy/TOP-SKILLS
Cloud laboratory platform for automated protein testing and validation. Use when designing proteins and needing experimental validation including binding assays, expressi — from…
Find differentially accessible chromatin regions between conditions using DiffBind or DESeq2. Use when comparing chromatin accessibility between treatment groups, cell ty — from…
MongoDB with Mongoose — schemas, models, aggregation pipelines, migrations, and Atlas connections. Use when designing collections, writing queries, or integrating MongoDB into…
Structured competitive analysis with feature matrices, SWOT, positioning maps, and UX review. Covers research frameworks, pricing comparison, review mining, and visual de — from…
When the user wants to run YouTube ads, set up TrueView or Bumper campaigns, or optimize video ad creative.
Multi-objective optimization framework. NSGA-II, NSGA-III, MOEA/D, Pareto fronts, constraint handling, benchmarks (ZDT, DTLZ), for engineering design and optimization pro — from…
Use when executing implementation plans with independent tasks in the current session — from bg-szy/TOP-SKILLS
Pythonic wrapper around RDKit with simplified interface and sensible defaults. Preferred for standard drug discovery including SMILES parsing, standardization, descriptor — from…
Run 250+ AI apps via inference.sh CLI - image generation, video creation, LLMs, search, 3D, Twitter automation.
Vendor-agnostic lab automation framework. Use when controlling multiple equipment types (Hamilton, Tecan, Opentrons, plate readers, pumps) or needing unified programming — from…
Spectral similarity and compound identification for metabolomics. Use for comparing mass spectra, computing similarity scores (cosine, modified cosine), and identifying u — from…
Calculate sequence statistics (N50, length distribution, GC content, summary reports) using Biopython.
Build reproducible bioinformatics pipelines with Snakemake using rules, wildcards, and automatic dependency resolution.
When the user wants to design, optimize, or audit hero sections (above-the-fold main visual area). Also use when the user mentions "hero," "hero section," "hero area," "above the…
Estimate causal effects of an exposure on an outcome from GWAS summary statistics using genetic instruments.
CRISPR library design for genetic screens. Covers sgRNA selection, library composition, control design, and oligo ordering.
Knowledge and utilities for creating animated GIFs optimized for Slack. Provides constraints, validation tools, and animation concepts.
Profile functional potential of metagenomes using HUMAnN3 and similar tools. Use when obtaining pathway abundances, gene family counts, or functional annotations from met — from…
Automate Twitter/X tasks via Rube MCP (Composio): posts, search, users, bookmarks, lists, media. Always search tools first for current schemas. — from bg-szy/TOP-SKILLS
Use when about to claim work is complete, fixed, or passing, before committing or creating PRs - requires running verification commands and confirming output before makin — from…
KEGG pathway and module enrichment analysis using clusterProfiler enrichKEGG and enrichMKEGG. Use when identifying metabolic and signaling pathways over-represented in a — from…
Build maximum likelihood phylogenetic trees using IQ-TREE2 and RAxML-NG with expert model selection, branch support assessment, and topology testing.
Use when executing implementation plans with independent tasks in the current session — from bg-szy/TOP-SKILLS
Download large datasets from NCBI efficiently using EPost, history server, batching, rate limiting, and retry logic.
Swap a face / character into video or images on RunComfy via the `runcomfy` CLI. Routes across community Wan 2-2 Animate (audio-driven character animation + identity swap — from…
Quantifies alternative splicing events (PSI/percent spliced in) from RNA-seq using SUPPA2 from transcript TPM or rMATS-turbo from BAM files.
Web search and content extraction with Tavily and Exa via inference.sh CLI. Apps: Tavily Search, Tavily Extract, Exa Search, Exa Answer, Exa Extract.
When the user wants to choose or execute third-party platform SEO (high-authority sites for rankings or backlinks).
Gene Ontology over-representation analysis using clusterProfiler enrichGO. Use when identifying biological functions enriched in a gene list from differential expression — from…
Generate images with Google Nano Banana 2 (Gemini-family flash-tier text-to-image) on RunComfy — bundled with the model's documented prompting patterns so the skill gets — from…
Comprehensive chemical safety and toxicology assessment integrating ADMET-AI predictions, CTD toxicogenomics, FDA label safety data, DrugBank safety profiles, and STITCH…
Generate and deploy a complete brand asset pack for a Next.js App Router project. Scans the project, prints what to generate with exact specs, then imports and wires everything…
Reconstruct cell lineage trees from CRISPR barcode tracing or mitochondrial mutations. Use when studying clonal dynamics, cell fate decisions, or developmental trajectori — from…
Corrects the gene-independent copy-number artifact in CRISPR-Cas9 screens (Aguirre 2016 / Munoz 2016 Cancer Discov) where amplified loci appear essential from DNA-damage — from…
Deploy a self-hosted funnel builder, take a funnel from empty install to published - landing page, checkout, one-click upsell, thank-you - and drive it from an agent over MCP.
Framework for computational fluid dynamics simulations using Python. Use when running fluid dynamics simulations including Navier-Stokes equations (2D/3D), shallow water — from…