Master SQL query optimization, indexing strategies, and EXPLAIN analysis to dramatically improve database performance and eliminate slow queries.
Render videos from React/Remotion component code via inference.sh. Pass TSX code, get MP4. Supports all Remotion APIs: useCurrentFrame, useVideoConfig, spring, interpolat — from…
Iterate on a PR until CI passes. Use when you need to fix CI failures, address review feedback, or continuously push fixes until all checks are green.
Fulfill an existing NLA escrow and collect tokens. Use when the user wants to submit fulfillment text for an on-chain escrow, check arbitration results, and collect appro — from…
Review the changes since a fixed point (commit, branch, tag, or merge-base) along two axes — Standards (does the code follow this repo's documented coding standards?) and — from…
Web search and content extraction with Tavily and Exa via inference.sh CLI. Apps: Tavily Search, Tavily Extract, Exa Search, Exa Answer, Exa Extract.
Predict TCR-epitope specificity using ERGO-II and deep learning models for T-cell receptor antigen recognition.
Design PCR primers for a target sequence using primer3-py. Specify target regions, product size, melting temperature, and other constraints.
Detect and quantify translated ORFs from Ribo-seq data including uORFs and novel ORFs using RiboCode and ORFquant.
Expert patterns for Neon serverless Postgres, branching, connection pooling, and Prisma/Drizzle integration Use when: neon database, serverless postgres, database branchi — from…
Assign cells to their sample of origin from cell or nucleus hashing (CITE-seq HTOs, MULTI-seq lipid/cholesterol tags, CellPlex CMOs) and call cross-sample doublets using Seurat…
Chooses the enrichment generation before any tool runs, mapping the input shape to a method class - a pre-selected gene list plus a background to over-representation analysis…
Ancient text restoration, attribution, dating, contextualization, and embedding via Aeneas (Latin) / Ithaca (Ancient Greek).
Design and implement event stores for event-sourced systems. Use when building event sourcing infrastructure, choosing event store technologies, or implementing event per — from…
Generate images with Google Gemini 3.1 Flash Image Preview (Nano Banana 2) via inference.sh CLI. Capabilities: text-to-image, image editing, multi-image input (up to 14 i — from…
Decompose total effects into direct and indirect paths through mediators using mediation, CMAverse 4-way, HIMA/HIMA2 high-dimensional, BAMA, two-step / MVMR mediation, or…
Senior FDA consultant and specialist for medical device companies including HIPAA compliance and requirement management.
Multi-agent orchestration patterns. Use when multiple independent tasks can run with different domain expertise or when comprehensive analysis requires multiple perspecti — from…
End-to-end small RNA-seq analysis from FASTQ to differential miRNA expression. Use when analyzing miRNA, piRNA, or other small RNA sequencing data. — from bg-szy/TOP-SKILLS
Verification discipline for completion claims. Use when about to assert success, claim a fix is complete, report tests passing, or before commits and PRs.
Use when starting any conversation - establishes how to find and use skills, requiring Skill tool invocation before ANY response including clarifying questions — from…
Master Python asyncio, concurrent programming, and async/await patterns for high-performance applications.
Complete mass spectrometry analysis platform. Use for proteomics workflows feature detection, peptide identification, protein quantification, and complex LC-MS/MS pipelin — from…
Use TweetClaw with OpenClaw to search tweets, search tweet replies, export followers, inspect users, monitor X/Twitter, and prepare reviewed post or reply actions.
Downloads videos from YouTube and other platforms for offline viewing, editing, or archival. Handles various formats and quality options. — from bg-szy/TOP-SKILLS
Senior Regulatory Affairs Manager expertise for HealthTech and MedTech companies. Provides strategic regulatory guidance, submission management, regulatory pathway analys — from…
Browser automation for AI agents via inference.sh. Navigate web pages, interact with elements using @e refs, take screenshots, record video.
UpdateStock MCP 服务技能 —— 通过 stdio 模式调用 UpdateStock 脚本， 提供 A 股 DuckDB 数据库管理功能：创建数据库、全量/增量更新股票数据、查询股票行情。 设计的数据库方案兼容 QuantAll（全A解析）计算引擎。…
Compare cell-type composition and spatial features across conditions in IMC/MIBI cohorts with the patient as the experimental unit, covering pseudoreplication, per-patient…
Diátaxis Documentation Expert. An expert technical writer specializing in creating high-quality software documentation, guided by the principles and structure of the Diátaxis…
Reviews plot structure, story beats, logic flow, and narrative continuity to identify contradictions, plot holes, pacing issues, or unrealistic elements.
Generate and maintain OpenAPI 3.1 specifications from code, design-first specs, and validation patterns.
Search and fetch structured content from Wikipedia using the MediaWiki API for reliable, encyclopedic information
Python SDK for inference.sh - run AI apps, build agents, and integrate with 150+ models. Package: inferencesh (pip install inferencesh).
YouTube thumbnail design with specific dimensions, contrast rules, and mobile preview optimization. Covers safe zones, text placement, face expression psychology, and A/B — from…
Use when facing 2+ independent tasks that can be worked on without shared state or sequential dependencies — from bg-szy/TOP-SKILLS
Use when Codex, Hermes, OpenClaw, Claude Code, Cowork, or another AI agent needs to plan, review, implement, audit, or improve email work focused on editorial calendars — from…
Use when about to claim work is complete, fixed, or passing, before committing or creating PRs - requires running verification commands and confirming output before makin — from…
Creates new Claude Code skills following best practices. Guides through skill structure, naming, descriptions, and progressive disclosure.
Deslop, humanize, edit, or audit AI-sounding, robotic, generic, corporate, or ChatGPT-like copy while preserving the writer's voice.
Generate and interpret quality reports from FASTQ files using FastQC and MultiQC. Assess per-base quality, adapter content, GC bias, duplication levels, and overrepresent — from…
Align RNA-seq reads with STAR (Spliced Transcripts Alignment to a Reference). Supports two-pass mode for novel splice junction discovery.
World-class prompt engineering skill for LLM optimization, prompt patterns, structured outputs, and AI product development.
Render videos from React/Remotion component code via inference.sh. Pass TSX code, get MP4. Supports all Remotion APIs: useCurrentFrame, useVideoConfig, spring, interpolat — from…
Query UniProt's REST API (post-2022 endpoint at rest.uniprot.org) for protein sequences, annotations, GO terms, cross-references, ID mappings, and proteomes.
Filter and select sequences by criteria (length, ID, GC content, patterns) using Biopython. Use when subsetting sequences, removing unwanted records, or selecting by spec — from…
Extract methylation calls from Bismark BAM files using bismark_methylation_extractor. Generates per-cytosine reports for CpG, CHG, and CHH contexts.
Graph Neural Networks (PyG). Node/graph classification, link prediction, GCN, GAT, GraphSAGE, heterogeneous graphs, molecular property prediction, for geometric deep lear — from…
Build OncoPrint and co-mutation matrix plots from somatic-variant cohorts using ComplexHeatmap, maftools, and comut.py with alteration-type stacking, sample ordering by mutational…
Automate Twitter/X with posting, engagement, and user management via inference.sh CLI. Apps: x/post-tweet, x/post-create (with media), x/post-like, x/post-retweet, x/dm-s — from…
Create AI agents and workflows using Microsoft Agent Framework SDK. Supports single-agent and multi-agent workflow patterns.
Optimize cloud costs through resource rightsizing, tagging strategies, reserved instances, and spending analysis.
DNA methylation analysis with methylKit in R. Import Bismark coverage files, filter by coverage, normalize samples, and perform statistical comparisons.
Generate images with Google Gemini 3.1 Flash Image Preview (Nano Banana 2) via inference.sh CLI. Capabilities: text-to-image, image editing, multi-image input (up to 14 i — from…
Preprocess CLIP-seq reads (eCLIP, iCLIP, iCLIP2, iCLIP3, irCLIP, PAR-CLIP, FLASH) with protocol-specific UMI extraction, adapter trimming, length filtering, and post-alignment…
End-to-end multiome workflow for joint scRNA-seq + scATAC-seq analysis. Covers data loading, separate modality processing, and WNN integration with Seurat/Signac.
Query the ClinPGx API for pharmacogenomic gene-drug data, clinical annotations, CPIC guidelines, and FDA drug labels
Gate a build on browser fingerprint regressions with liarjs - save a baseline scan as JSON, diff later runs against it, and fail the job when the consistency score falls below a…
Orchestrate iOS/macOS app scaffolding and optional skill adoption for existing projects. Use when users want a guided wizard that can scaffold with XcodeGen and optionally install…
Region edits across video frames on RunComfy via the `runcomfy` CLI — remove an object that appears across many frames, clean up wires or watermarks, replace a region wit — from…